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Displaying toxin 76 - 100 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2610Alpha-hemolysin
94716-94-6
Not Available
35904.070 g/mol
T3d2610
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Alpha-hemolysin consists mainly of beta-sheets forms heptameric units on the cellular membrane, producing a complete beta-barrel pore. This pore allows the exchange of...more
Number of Targets: 0
T3D2611Beta-hemolysin
143257-99-2
Not Available
37237.665 g/mol
T3d2611
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Hemolysins consists mainly of beta-sheets forms heptameric units on the cellular membrane, producing a complete beta-barrel pore. This pore allows the exchange of mono...more
Number of Targets: 0
T3D2612Delta-hemolysin
74838-20-3
Not Available
2978.515 g/mol
T3d2612
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Hemolysins consists mainly of beta-sheets forms heptameric units on the cellular membrane, producing a complete beta-barrel pore. This pore allows the exchange of mono...more
Number of Targets: 0
T3D2613Leukocidin S
Not Available
Not Available
35556.550 g/mol
T3d2613
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Leukocidin S and leukocidin F act together as subunits, assembling in the membrane of host defense cells, particularly white blood cells, monocytes and macrophages. Th...more
Number of Targets: 0
T3D2614Leukocidin F
147096-70-6
Not Available
36566.730 g/mol
T3d2614
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Leukocidin S and leukocidin F act together as subunits, assembling in the membrane of host defense cells, particularly white blood cells, monocytes and macrophages. Th...more
Number of Targets: 0
T3D2618Enterotoxin type A
Not Available
Not Available
29669.310 g/mol
T3d2618
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of intestinal mucosal cells. These membrane pores are activated by eithe...more
Number of Targets: 0
T3D2619Enterotoxin type B
Not Available
Not Available
31435.675 g/mol
T3d2619
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of intestinal mucosal cells. These membrane pores are activated by eithe...more
Number of Targets: 0
T3D2620Pneumolysin
Not Available
Not Available
52898.050 g/mol
T3d2620
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pneumolysin binds to cholesterol the undergoes oligomerization and membrane pore formation. Pneumolysin also activates the classical pathway of complement. Mutational ...more
Number of Targets: 1
T3D2622Streptolysin O (Streptococcus pyogenes)
98072-47-0
Not Available
63637.990 g/mol
T3d2622
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Streptolysin O binds to cholesterol on eukaryotic cell membranes, then is able to lyse them. (T170)
Number of Targets: 1
T3D2623Cholera toxin
9012-63-9
Not Available
29335.385 g/mol
T3d2623
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
The effect is dependent on a specific receptor, monosialosyl ganglioside (GM1 ganglioside) present on the surface of intestinal mucosal cells. Once it has entered the ...more
Number of Targets: 2
T3D2624Melittin (Apis mellifera)
20449-79-0
Not Available
7584.775 g/mol
T3d2624
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Melittin has strong haemolytic activity. It integrates into cell membranes and has multiple effects, probably, as a result of its interaction with negatively charged p...more
Number of Targets: 12
T3D2625Lopap
Not Available
Not Available
22432.280 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Lopap activates thrombin by cleavage of prothrombin, causing thrombus formation, fibrinogen depletion, uncoagulable blood, decreased platelet count, inhibition of coll...more
Number of Targets: 0
T3D2627mu-Agatoxin
120500-28-9
Not Available
4272.715 g/mol
T3d2627
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
mu-Agatoxins modify presynaptic voltage-activated sodium channels in the neuromuscular joints of insects. Modifying sodium channels leads to an increased sensitivity o...more
Number of Targets: 0
T3D2628kappa-Atracotoxin (Hadronyche versuta)
Not Available
Not Available
3685.155 g/mol
T3d2628
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
kappa-Atracotoxins inhibit insect voltage-gated potassium channels. (T170, L1812)
Number of Targets: 0
T3D2629Hanatoxin
170780-01-5
Not Available
4120.690 g/mol
T3d2629
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it does by occupying multiple binding sites on the channel. It can also in...more
Number of Targets: 3
T3D2630Sphingomyelinase D (Loxosceles intermedia)
9031-54-3
Not Available
34158.125 g/mol
T3d2630
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemolysis, dermonecrosis, blood vessel permeability and platelet aggregati...more
Number of Targets: 0
T3D2631Heteroscodratoxin
Not Available
Not Available
4003.400 g/mol
T3d2631
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Heteroscodratoxin inhibits voltage-gated potassium channels by binding to the extracellular linker of the channel and shifting activation of the channel to more depola...more
Number of Targets: 5
T3D2633Acanthophin
126601-49-8
Not Available
8386.795 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Acanthophin produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. It does this by binding to certain muscular and neuronal nic...more
Number of Targets: 8
T3D2635Erabutoxin
59536-69-5
Not Available
9136.510 g/mol
T3d2635
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Erabutoxin binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), and with low affinity to neuronal alpha-7 nAChRs. This produces peripheral ...more
Number of Targets: 6
T3D2636Disintegrin echistatin (Echis carinatus)
Not Available
Not Available
5424.090 g/mol
T3d2636
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more
Number of Targets: 2
T3D2637Nigroxin
9001-84-7
Not Available
13341.125 g/mol
T3d2637
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Nigroxin is myotoxic. (T170)
Number of Targets: 0
T3D2638Notexin
37233-96-4
Not Available
13593.310 g/mol
T3d2638
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Notexin is myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. (T170)
Number of Targets: 0
T3D2639Ohanin
Not Available
Not Available
21173.945 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Ohanin is extremely neurotoxic, cardiotoxic, and cytotoxic. (L1102)
Number of Targets: 0
T3D2640Pseudechetoxin
Not Available
Not Available
26474.445 g/mol
T3d2640
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Pseudechetoxin blocks olfactory and retinal cyclic nucleotide-gated (CNG) ion channel currents. It forms high-affinity contacts with the pore turret region and most li...more
Number of Targets: 2
T3D2642Viperotoxin
Not Available
Not Available
15554.775 g/mol
T3d2642
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Viperotoxin is a presynaptic neurotoxin. (T170)
Number of Targets: 0
Displaying toxin 76 - 100 of 3678 in total