Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |  |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 |
| T3D2702 | (R)-lipoic acid 62-46-4 | C8H14O2S2 206.326 g/mol |  |
| (R)-lipoic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholi...more Number of Targets: 6 |
| T3D2534 | Bufotenin 487-93-4 | C12H16N2O 204.268 g/mol |  |
| Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more Number of Targets: 4 |
| T3D4369 | L-Tryptophan 73-22-3 | C11H12N2O2 204.225 g/mol |  |
| A number of important side reactions occur during the catabolism of tryptophan on the pathway to acetoacetate. The first enzyme of the catabolic pathway is an iron por...more Number of Targets: 7 |
| T3D4883 | Sebacic acid 111-20-6 | C10H18O4 202.248 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4999 | Succinyl acetoacetate 65115-74-4 | C8H10O6 202.161 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4434 | S-Sulfocysteine 1637-71-4 | C3H6NO5S2 200.214 g/mol |  |
| S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have shown that SSC displays depolarizing properties similar to glutamate. S...more Number of Targets: 3 |
| T3D4960 | Galactonic acid 13382-27-9 | C6H12O7 196.155 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4967 | L-Dopaquinone 110810-88-3 | C9H9NO4 195.172 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4991 | 9-Hydroxyphenanthrene 484-17-3 | C14H10O 194.229 g/mol |  |
| 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whos...more Number of Targets: 0 |
| T3D3961 | Monoethyl phthalate 2306-33-4 | C10H10O4 194.184 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4966 | 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid 3247-75-4 | C9H10O4 182.173 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4371 | L-Tyrosine 60-18-4 | C9H11NO3 181.189 g/mol |  |
| Tyrosine is produced in cells by hydroxylating the essential amino acid phenylalanine. This relationship is much like that between cysteine and methionine. Half of the...more Number of Targets: 5 |
| T3D4201 | Caffeic acid 331-39-5 | C9H8O4 180.157 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4356 | D-Glucose 50-99-7 | C6H12O6 180.156 g/mol |  |
| Very high serum levels of glucose are found in untreated diabetic (type I or type II) patients. Glucose in chronic excess causes toxic effects on the structure and fun...more Number of Targets: 33 |
| T3D4345 | D-Fructose 53188-23-1 | C6H12O6 180.156 g/mol |  |
| Fructose is distinct from other sugars in its ability to cause intracellular ATP depletion, nucleotide turnover, and the generation of uric acid. Uric acid is generate...more Number of Targets: 5 |
| T3D0301 | Arsenobetaine 64436-13-1 | C5H11AsO2 178.061 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D3956 | Cotinine 486-56-6 | C10H12N2O 176.215 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4295 | Citrulline 372-75-8 | C6H13N3O3 175.186 g/mol |  |
| L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's act...more Number of Targets: 13 |
| T3D4310 | N-Acetyl-L-aspartic acid 997-55-7 | C6H9NO5 175.139 g/mol |  |
| The primary proposed functions of N-acetylaspartic acid include: 1) A neuronal osmolyte that is involved in fluid balance in the brain; 2) a source of acetate for lipi...more Number of Targets: 0 |
| T3D4289 | L-Arginine 74-79-3 | C6H14N4O2 174.201 g/mol |  |
| Many of supplemental L-arginine's activities, including its possible anti-atherogenic actions, may be accounted for by its role as the precursor to nitric oxide or NO....more Number of Targets: 9 |
| T3D4959 | Pyrophosphate 14000-31-8 | O7P2 173.946 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4773 | Capric acid 334-48-5 | C10H20O2 172.265 g/mol |  |
| It has been demonstrated that octanoic (OA) and decanoic (DA) acids compromise the glycolytic pathway and citric acid cycle functioning, increase oxygen consumption in...more Number of Targets: 4 |
| T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |  |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |