Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |  |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D2647 | Stonustoxin Not Available | Not Available 79523.640 g/mol | |
| Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more Number of Targets: 0 |
| T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol | |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 |
| T3D2649 | Box jellyfish toxin (Chironex fleckeri) Not Available | Not Available 51389.865 g/mol | |
| Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells...more Number of Targets: 0 |
| T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |  |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 |
| T3D2657 | alpha-Conotoxin (Conus geographus) Not Available | Not Available 1627.830 g/mol |  |
| alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107) Number of Targets: 15 |
| T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |  |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 |
| T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |  |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 |
| T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |  |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 |
| T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |  |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 |
| T3D2490 | alpha-Pompilidotoxin 202075-91-0 | Not Available 1530.850 g/mol |  |
| Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more Number of Targets: 10 |
| T3D2477 | Insulin 11061-68-0 | Not Available 11980.795 g/mol |  |
| Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more Number of Targets: 56 |
| T3D2491 | beta-Pompilidotoxin 216064-36-7 | Not Available 1558.860 g/mol |  |
| Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more Number of Targets: 10 |
| T3D2492 | Holocyclotoxin 88254-04-0 | Not Available 7834.125 g/mol |  |
| Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) Number of Targets: 0 |
| T3D2493 | Poneratoxin 137084-94-7 | Not Available 2757.330 g/mol |  |
| Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019) Number of Targets: 14 |
| T3D2494 | omega-Agatoxin 145017-83-0 | Not Available 12807.575 g/mol |  |
| omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more Number of Targets: 1 |
| T3D2495 | Atracotoxin, omega- (Hadronyche versuta) 193981-10-1 | Not Available 4055.410 g/mol |  |
| omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812) Number of Targets: 0 |
| T3D2496 | Versutoxin 114264-83-4 | Not Available 4855.645 g/mol |  |
| Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D2497 | Robustoxin 91728-12-0 | Not Available 4856.685 g/mol |  |
| Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D2498 | Grammotoxin 152617-90-8 | Not Available 9600.980 g/mol |  |
| Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more Number of Targets: 3 |
| T3D2499 | Huwentoxin 526224-73-7 | Not Available 9318.830 g/mol |  |
| Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more Number of Targets: 17 |
| T3D2500 | alpha-Latrotoxin 65988-34-3 | Not Available 156855.500 g/mol |  |
| alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more Number of Targets: 10 |
| T3D2501 | Phrixotoxin 880886-00-0 or 221872-97-5 | Not Available 3555.310 g/mol |  |
| Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170) Number of Targets: 2 |
| T3D2502 | Stromatoxin 1262235-00-6 | Not Available 3798.295 g/mol | |
| Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more Number of Targets: 4 |
| T3D2503 | Phoneutriatoxin Not Available | Not Available 12677.715 g/mol | |
| Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) Number of Targets: 3 |