Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2534 | Bufotenin 487-93-4 | C12H16N2O 204.268 g/mol |  |
| Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more Number of Targets: 4 |
| T3D2532 | Arenobufagin 464-74-4 | C24H32O6 416.507 g/mol |  |
| Arenobufagin blocks the sodium/potassium pump in heart tissue. (L1078) Number of Targets: 8 |
| T3D2531 | Allopumiliotoxin 73376-38-2 | C16H29NO2 267.407 g/mol |  |
| Allopumiliotoxins may affect sodium and potassium channels in cells and inhibit calcium-dependent ATPase. (L1077, A313, A315) Number of Targets: 11 |
| T3D2530 | Epibatidine 140111-52-0 | C11H13ClN2 208.687 g/mol |  |
| Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) Number of Targets: 17 |
| T3D2529 | Pumiliotoxin 73376-35-9 | C16H29NO 251.408 g/mol |  |
| Pumiliotoxin affects voltage-gated calcium channels, interfering with muscle contraction in the heart and skeletal muscle. They also may block sodium and potassium cha...more Number of Targets: 25 |
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D2527 | Batrachotoxin 23509-16-2 | C31H42N2O6 538.675 g/mol |  |
| Batrachotoxins act on sodium channels by modifying both their ion selectivity and voltage sensitivity. By increasing the permeability of the cell membrane, the cell is...more Number of Targets: 14 |
| T3D2526 | Tityustoxin (Tityus serrulatus ) 39465-37-7 | Not Available 6997.935 g/mol |  |
| Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more Number of Targets: 14 |
| T3D2525 | Tamapin 508220-81-3 | Not Available 3465.100 g/mol |  |
| Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more Number of Targets: 3 |
| T3D2524 | Slotoxin 144026-79-9 | Not Available 4091.850 g/mol |  |
| Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha-subunits and irreversibly blocks the high conductance calci...more Number of Targets: 3 |
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D2522 | Noxiustoxin 85205-49-8 | Not Available 4201.920 g/mol |  |
| Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more Number of Targets: 23 |
| T3D2521 | Maurotoxin 188240-41-7 | Not Available 3621.205 g/mol |  |
| Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059) Number of Targets: 7 |
| T3D2520 | Margatoxin 145808-47-5 | Not Available 4184.990 g/mol |  |
| Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurotransmitter release. (L1057) Number of Targets: 1 |
| T3D2519 | Kurtoxin 820959-57-7 | Not Available 7394.400 g/mol |  |
| Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium channels Kurtoxin binds close to the channel voltage sensor and thereby p...more Number of Targets: 14 |
| T3D2518 | Kaliotoxin-3 223246-26-2 | Not Available 4027.840 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2517 | Kaliotoxin-2 159605-22-8 | Not Available 6392.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2516 | Kaliotoxin-1 150769-72-5 | Not Available 4155.975 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2515 | Kaliotoxin 145199-73-1 | Not Available 6461.905 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol | |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D2512 | Iberiotoxin 129203-60-7 | Not Available 4253.920 g/mol |  |
| Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more Number of Targets: 5 |
| T3D2511 | kappa-Hefutoxin 478621-50-0 | Not Available 2659.865 g/mol |  |
| kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Number of Targets: 2 |
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2509 | Cobatoxin 211688-17-4 | Not Available 7131.365 g/mol |  |
| Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Number of Targets: 7 |