Browsing Toxins
Displaying toxin 3101 - 3125 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3920 | S-Bioallethrin 28434-00-6 | C19H26O3 302.408 g/mol |  |
| Not Available Number of Targets: 20 |
| T3D4434 | S-Sulfocysteine 1637-71-4 | C3H6NO5S2 200.214 g/mol |  |
| S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have shown that SSC displays depolarizing properties similar to glutamate. S...more Number of Targets: 3 |
| T3D4398 | Saccharopine 997-68-2 | C11H20N2O6 276.286 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4212 | Safrole 94-59-7 | C10H10O2 162.185 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4281 | SAICAR 3031-95-6 | C13H19N4O12P 454.283 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4735 | Salbutamol 18559-94-9 | C13H21NO3 239.311 g/mol |  |
| Salbutamol is a beta(2)-adrenergic agonist and thus it stimulates beta(2)-adrenergic receptors. Binding of albuterol to beta(2)-receptors in the lungs results in relax...more Number of Targets: 2 |
| T3D0680 | Salcomine 14167-18-1 | C16H16CoN2O2 327.244 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4816 | Salicylic acid 69-72-7 | C7H6O3 138.121 g/mol |  |
| Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostagla...more Number of Targets: 4 |
| T3D4734 | Salmeterol 89365-50-4 | C25H37NO4 415.566 g/mol |  |
| Salmeterol's long, lipophilic side chain binds to exosites near beta(2)-receptors in the lungs and on bronchiolar smooth muscle, allowing the active portion of the mol...more Number of Targets: 1 |
| T3D3532 | Salvinorin A 83729-01-5 | C23H28O8 432.464 g/mol |  |
| Salvinorin A, the active component of the hallucinogenic sage Salvia divinorum, is an apparently selective and highly potent kappa-opioid receptor (KOR) agonist. Salvi...more Number of Targets: 3 |
| T3D4619 | Sambunigrin 99-19-4 | C14H17NO6 295.288 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 0 |
| T3D4022 | Sanguinarine 2447-54-3 | C20H14NO4 332.329 g/mol |  |
| Sanguinarine, at micromolar concentrations, imparts cell growth inhibitory response in human squamous carcinoma (A431) cells via an induction of apoptosis. This is whi...more Number of Targets: 0 |
| T3D4458 | Sarcosine 107-97-1 | C3H7NO2 89.093 g/mol |  |
| Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent oncoprotein called human epidermal growth factor receptor 2 (HER2/neu) in ...more Number of Targets: 2 |
| T3D3712 | Satratoxin H 53126-64-0 | C29H36O9 528.591 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D2551 | Saxitoxin 35523-89-8 | C10H17N7O4 299.287 g/mol |  |
| Saxitoxin blocks voltage-gated sodium channels of nerve cells. (L1115) Number of Targets: 14 |
| T3D3713 | Scirpene 37133-74-7 | C15H22O2 234.334 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D2877 | Scopolamine 51-34-3 | C17H21NO4 303.353 g/mol |  |
| Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center). Number of Targets: 6 |
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D4883 | Sebacic acid 111-20-6 | C10H18O4 202.248 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3774 | Secalonic Acid D 35287-69-5 | C32H30O14 638.572 g/mol |  |
| Secalonic acid D (SAD) is though to induce cleft palate by causing the formation of smaller palatal shelves that fail to elevate and fuse. This inhibited palatal shelf...more Number of Targets: 4 |
| T3D2784 | Secobarbital 76-73-3 | C12H18N2O3 238.283 g/mol |  |
| Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open....more Number of Targets: 11 |
| T3D2965 | Selegiline 14611-51-9 | C13H17N 187.281 g/mol |  |
| Although the mechanisms for selegiline's beneficial action in the treatment of Parkinson's disease are not fully understood, the selective, irreversible inhibition of ...more Number of Targets: 4 |
| T3D1815 | Selenic acid 7783-08-6 | H2O4Se 144.970 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D0147 | Selenium 7782-49-2 | Se 78.960 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1841 | Selenium dimethyldithiocarbamate 144-34-3 | C12H24N4S8Se 559.830 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |