Browsing Toxins
Displaying toxin 3151 - 3175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1303 | p-Azobenzenearsonate 7334-23-8 | C12H12As2N2O6 430.077 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1884 | Tetrabutylantimony(V) bromide 45212-19-9 | C16H36BrSb 430.120 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4818 | Bicalutamide 90357-06-5 | C18H14F4N2O4S 430.373 g/mol |  |
| Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimula...more Number of Targets: 5 |
| T3D1744 | Phosphorus pentabromide 7789-69-7 | Br5P 430.494 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D2700 | Alpha-Tocopherol 59-02-9 | C29H50O2 430.706 g/mol |  |
| Although all forms of Vitamin E exhibit antioxidant activity, it is known that the antioxidant activity of vitamin E is not sufficient to explain the vitamin's biologi...more Number of Targets: 11 |
| T3D4535 | Rimsulfuron 122931-48-0 | C14H17N5O7S2 431.444 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D1633 | Vanadium(III) iodide 15513-94-7 | I3V 431.655 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D3607 | Ochratoxin C 4865-85-4 | C22H22ClNO6 431.866 g/mol |  |
| Ochratoxin A, a metabolite of Ochratoxin C, has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage. The nephrotoxin ochratoxin A (OTA) ca...more Number of Targets: 3 |
| T3D2825 | Benzthiazide 91-33-8 | C15H14ClN3O4S3 431.937 g/mol |  |
| As a diuretic, benzthiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of ...more Number of Targets: 7 |
| T3D3532 | Salvinorin A 83729-01-5 | C23H28O8 432.464 g/mol |  |
| Salvinorin A, the active component of the hallucinogenic sage Salvia divinorum, is an apparently selective and highly potent kappa-opioid receptor (KOR) agonist. Salvi...more Number of Targets: 3 |
| T3D4825 | Ilepatril 473289-62-2 | C22H28N2O5S 432.533 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3748 | Paspalinine 63722-91-8 | C27H31NO4 433.539 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D1031 | Cyfluthrin 68359-37-5 | C22H18Cl2FNO3 434.288 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 35 |
| T3D3856 | Halosulfuron-methyl 100784-20-1 | C13H15ClN6O7S 434.812 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3780 | Paxilline 57186-25-1 | C27H33NO4 435.555 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D2489 | Philanthotoxin 77108-00-0 | C23H41N5O3 435.603 g/mol |  |
| Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016) Number of Targets: 9 |
| T3D1880 | Potassium pyroantimonate 10090-54-7 | H2K2O7Sb2 435.730 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1285 | Azocyclotin 41083-11-8 | C20H35N3Sn 436.220 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D4923 | C.I. Food Red 1 4548-53-2 | C18H16N2O7S2 436.459 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2920 | Flupenthixol 2709-56-0 | C23H27F3N2OS 436.533 g/mol |  |
| Flupenthixol is a thioxanthene antipsychotic. The mechanism of action of Flupenthixol is not completely understood. Flupenthixol is a powerful antagonist of both D1 an...more Number of Targets: 8 |
| T3D1731 | Gold(III) bromide 10294-28-7 | AuBr3 436.679 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0798 | Fipronil 120068-37-3 | C12H4Cl2F6N4OS 437.148 g/mol |  |
| Fipronil blocks the passage of chloride ions through the GABA-regulated chloride channel, disrupting CNS activity. (T10) Organic nitriles decompose into cyanide ions b...more Number of Targets: 29 |
| T3D2840 | Fluphenazine 69-23-8 | C22H26F3N3OS 437.522 g/mol |  |
| Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believ...more Number of Targets: 17 |
| T3D4088 | Lyngbyatoxin A 70497-14-2 | C27H39N3O2 437.618 g/mol |  |
| Lyngbyatoxin A is a tumor promoter. Lyngbyatoxin A and related compounds bind to the cysteine-rich C1 domains (C1A and C1B) of protein kinase C (PKC) isozymes to activ...more Number of Targets: 2 |
| T3D1887 | Triethyloxonium hexachloroantimonate 3264-67-3 | C6H15Cl6OSb 437.660 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |