Browsing Toxins
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0084 | Hydrazine 302-01-2 | H4N2 32.045 g/mol |  |
| At least two mechanisms of action have been observed. One involves the direct binding of those hydrazines with a free amino group (hydrazine and 1,1-dimethylhydrazine)...more Number of Targets: 0 |
| T3D0259 | Phosphine 7803-51-2 | H3P 33.998 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D0191 | Hydrogen sulfide 7783-06-04 | H2S 34.081 g/mol |  |
| Although very pungent at first, hydrogen sulfide quickly deadens the sense of smell, so potential victims may be unaware of its presence until it is too late. Hydrogen...more Number of Targets: 1 |
| T3D0091 | Chloride ion 22537-115-1 | Cl 35.454 g/mol |  |
| Chloride imbalances can lead to electrolyte and pH imbalances. Excessive chloride in the blood is known as hyperchloremia. Often hyperchloremia is associated with ex...more Number of Targets: 16 |
| T3D4968 | Hydrochloric acid 7647-01-0 | ClH 36.461 g/mol |  |
| Both hydrogen chloride gas and hydrochloric acid are highly corrosive. Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysi...more Number of Targets: 0 |
| T3D4998 | Sulfur-35 15117-53-0 | H2S 36.985 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1495 | Aluminium diboride 12041-50-8 | AlB 37.793 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1503 | Lithium aluminium hydride 16853-85-3 | AlH4Li 37.954 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4344 | Potassium 7440-09-7 | K 39.098 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0217 | Potassium-40 13966-00-2 | K 39.964 g/mol |  |
| The ionizing radiation produced by potassium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more Number of Targets: 1 |
| T3D4405 | Calcium 7440-70-2 | Ca 40.077 g/mol |  |
| Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human ...more Number of Targets: 17 |
| T3D1517 | Aluminium nitride 24304-00-5 | AlN 40.988 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1652 | Methyl isocyanide 593-75-9 | C2H3N 41.052 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 40 |
| T3D1685 | Acetonitrile 75-05-8 | C2H3N 41.052 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D2408 | Boron phosphide 20205-91-8 | BP 41.785 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D3816 | Cyanamide 420-04-2 | CH2N2 42.040 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 5 |
| T3D0777 | Isocyanic acid 75-13-8 | CHNO 43.025 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D0646 | Beryllium hydroxide 13327-32-7 | BeH2O2 43.027 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D2563 | Carbon dioxide 124-38-9 | CO2 44.010 g/mol |  |
| Carbon dioxide causes widespread activation of the sympathetic nervous system and an increase in the plasma concentrations of epinephrine, norepinephrine, angiotensin,...more Number of Targets: 1 |
| T3D3471 | Acetaldehyde 75-07-0 | C2H4O 44.053 g/mol |  |
| Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (A354) Number of Targets: 1 |
| T3D4207 | Ethylene Oxide 75-21-8 | C2H4O 44.053 g/mol |  |
| Ethylene oxide is an alkylating agent. The addition of alkyl groups to proteins, DNA, and RNA by binding to the sulfhydryl and hydroxyl, amino, and carboxyl groups, pr...more Number of Targets: 0 |
| T3D4148 | Dimethylamine 124-40-3 | C2H7N 45.084 g/mol |  |
| Uremic toxins such as dimethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can sti...more Number of Targets: 5 |
| T3D4185 | Ethylamine 75-04-7 | C2H7N 45.084 g/mol |  |
| Uremic toxins such as ethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 3 |
| T3D1513 | Aluminium monofluoride 13595-82-9 | AlF 45.980 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0212 | Nitrite 14797-65-0 | NO2 46.006 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |