Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2489 | Philanthotoxin 77108-00-0 | C23H41N5O3 435.603 g/mol |  |
| Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016) Number of Targets: 9 |
| T3D2462 | Palytoxin 77734-91-9 | C129H223N3O53 2664.139 g/mol |  |
| Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the molecule is locked in a position where it allows passive transport of both...more Number of Targets: 9 |
| T3D4797 | Palmitic acid 57-10-3 | C16H32O2 256.424 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D4257 | Oxoadipic acid 3184-35-8 | C6H8O5 160.125 g/mol |  |
| In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. Accumulation ...more Number of Targets: 1 |
| T3D4292 | Orotic acid 65-86-1 | C5H4N2O4 156.096 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2550 | Onchidal 67656-42-2 | C17H24O3 276.371 g/mol |  |
| Onchidal is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 1 |
| T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |  |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 |
| T3D2494 | omega-Agatoxin 145017-83-0 | Not Available 12807.575 g/mol |  |
| omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more Number of Targets: 1 |
| T3D4802 | Oleic acid 112-80-1 | C18H34O2 282.461 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4029 | Okadaic acid 78111-17-8 | C44H68O13 805.003 g/mol |  |
| Okadaic acid (OA) dramatically increases both nerve growth factor (NGF) mRNA content (50-fold) and NGF secretion (100-fold) in astrocytes. Okadaic acid also activated ...more Number of Targets: 1 |
| T3D2639 | Ohanin Not Available | Not Available 21173.945 g/mol |  |
| Ohanin is extremely neurotoxic, cardiotoxic, and cytotoxic. (L1102) Number of Targets: 0 |
| T3D3965 | O-Desmethylangolensin 21255-69-6 | C15H14O4 258.269 g/mol |  |
| O-desmethylangolensin (ODMA) exerts androgen receptor antagonistic activity and agonistic activity towards estrogen receptor (ER)-α and ERβ. The structure of ODMA is s...more Number of Targets: 2 |
| T3D2522 | Noxiustoxin 85205-49-8 | Not Available 4201.920 g/mol |  |
| Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more Number of Targets: 23 |
| T3D2638 | Notexin 37233-96-4 | Not Available 13593.310 g/mol |  |
| Notexin is myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2637 | Nigroxin 9001-84-7 | Not Available 13341.125 g/mol |  |
| Nigroxin is myotoxic. (T170) Number of Targets: 0 |
| T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol | |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 |
| T3D4023 | Neosaxitoxin 64296-20-4 | C10H17N7O5 315.286 g/mol |  |
| Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated sodium channels in a very powerful and reversible manner, without affe...more Number of Targets: 0 |
| T3D4310 | N-Acetyl-L-aspartic acid 997-55-7 | C6H9NO5 175.139 g/mol |  |
| The primary proposed functions of N-acetylaspartic acid include: 1) A neuronal osmolyte that is involved in fluid balance in the brain; 2) a source of acetate for lipi...more Number of Targets: 0 |
| T3D4599 | Myristic acid 544-63-8 | C14H28O2 228.371 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2584 | Myotoxin (Crotalus viridis viridis) 132821-30-8 | Not Available 4827.755 g/mol |  |
| Myotoxins work by a non-enzymatic mechanism that leads to severe muscle necrosis, causing paralysis and eventually death. They may also modify voltage-sensitive sodium...more Number of Targets: 14 |
| T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |  |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 |
| T3D2627 | mu-Agatoxin 120500-28-9 | Not Available 4272.715 g/mol |  |
| mu-Agatoxins modify presynaptic voltage-activated sodium channels in the neuromuscular joints of insects. Modifying sodium channels leads to an increased sensitivity o...more Number of Targets: 0 |
| T3D3960 | Monoisobutyl phthalic acid 30833-53-5 | C12H14O4 222.237 g/mol |  |
| Phthalates are synthetic industrial compounds capable of disrupting the endocrine system. The phthalates have been the most common chemical compounds with the ability ...more Number of Targets: 4 |
| T3D3973 | Monoethylhexyl phthalic acid 4376-20-9 | C16H22O4 278.344 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3961 | Monoethyl phthalate 2306-33-4 | C10H10O4 194.184 g/mol |  |
| Not Available Number of Targets: 3 |