Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4363 | L-Histidine 71-00-1 | C6H9N3O2 155.155 g/mol |  |
| Since the actions of supplemental L-histidine are unclear, any postulated mechanism is entirely speculative. However, some facts are known about L-histidine and some o...more Number of Targets: 5 |
| T3D4319 | L-Glutamine 56-85-9 | C5H10N2O3 146.145 g/mol |  |
| Supplemental L-glutamine's possible immunomodulatory role may be accounted for in a number of ways. L-glutamine appears to play a major role in protecting the integrit...more Number of Targets: 3 |
| T3D4296 | L-Glutamic acid 56-86-0 | C5H9NO4 147.129 g/mol |  |
| Glutamate activates both ionotropic and metabotropic glutamate receptors. The ionotropic ones being non-NMDA (AMPA and kainate) and NMDA receptors. Free glutamic acid ...more Number of Targets: 76 |
| T3D4967 | L-Dopaquinone 110810-88-3 | C9H9NO4 195.172 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4362 | L-Asparagine 70-47-3 | C4H8N2O3 132.118 g/mol |  |
| Asparagine, a non-essential amino acid is important in the metabolism of toxic ammonia in the body through the action of asparagine synthase which attaches ammonia to ...more Number of Targets: 6 |
| T3D4289 | L-Arginine 74-79-3 | C6H14N4O2 174.201 g/mol |  |
| Many of supplemental L-arginine's activities, including its possible anti-atherogenic actions, may be accounted for by its role as the precursor to nitric oxide or NO....more Number of Targets: 9 |
| T3D4320 | L-Alanine 56-41-7 | C3H7NO2 89.093 g/mol |  |
| L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar...more Number of Targets: 13 |
| T3D4247 | L-2-Hydroxyglutaric acid 13095-48-2 | C5H8O5 148.114 g/mol |  |
| 2-hydroxyglutarate is an oncometabolite. It is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET f...more Number of Targets: 16 |
| T3D2519 | Kurtoxin 820959-57-7 | Not Available 7394.400 g/mol |  |
| Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium channels Kurtoxin binds close to the channel voltage sensor and thereby p...more Number of Targets: 14 |
| T3D4426 | Ketoleucine 816-66-0 | C6H10O3 130.142 g/mol |  |
| Ketoleucine is a metabolite that accumulates in Maple Syrup Urine Disease (MSUD) and shown to compromise brain energy metabolism by blocking the respiratory chain. Number of Targets: 0 |
| T3D2511 | kappa-Hefutoxin 478621-50-0 | Not Available 2659.865 g/mol |  |
| kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Number of Targets: 2 |
| T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |  |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 |
| T3D2628 | kappa-Atracotoxin (Hadronyche versuta) Not Available | Not Available 3685.155 g/mol |  |
| kappa-Atracotoxins inhibit insect voltage-gated potassium channels. (T170, L1812) Number of Targets: 0 |
| T3D2518 | Kaliotoxin-3 223246-26-2 | Not Available 4027.840 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2517 | Kaliotoxin-2 159605-22-8 | Not Available 6392.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2516 | Kaliotoxin-1 150769-72-5 | Not Available 4155.975 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2515 | Kaliotoxin 145199-73-1 | Not Available 6461.905 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2477 | Insulin 11061-68-0 | Not Available 11980.795 g/mol |  |
| Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more Number of Targets: 56 |
| T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |  |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol | |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2512 | Iberiotoxin 129203-60-7 | Not Available 4253.920 g/mol |  |
| Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more Number of Targets: 5 |
| T3D4304 | Hydroxypropionic acid 503-66-2 | C3H6O3 90.078 g/mol |  |
| 3-hydroxypropionic acid (3HP) toxicity is mediated by 3-hydroxypropionic aldehyde (reuterin). 3HP toxicity is also proposed to be related to inhibition of the chorisma...more Number of Targets: 0 |
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol | |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D2499 | Huwentoxin 526224-73-7 | Not Available 9318.830 g/mol |  |
| Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more Number of Targets: 17 |