Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4439 | Protoporphyrinogen IX 7412-77-3 | C34H40N4O4 568.706 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4440 | Protoporphyrin IX 553-12-8 | C34H34N4O4 562.658 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3233 | CE(10:0) 1183-04-6 | C37H64O2 540.903 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2527 | Batrachotoxin 23509-16-2 | C31H42N2O6 538.675 g/mol |  |
| Batrachotoxins act on sodium channels by modifying both their ion selectivity and voltage sensitivity. By increasing the permeability of the cell membrane, the cell is...more Number of Targets: 14 |
| T3D4051 | Gymnodimine 173792-58-0 | C32H45NO4 507.704 g/mol |  |
| Gymnodimine exerts its toxic effects via binding to nicotinic acetylcholine receptors with picomolar affinities with no sign of apparent reversibility in short time fr...more Number of Targets: 0 |
| T3D4276 | Adenosine triphosphate 56-65-5 | C10H16N5O13P3 507.181 g/mol |  |
| ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cel...more Number of Targets: 42 |
| T3D2524 | Slotoxin 144026-79-9 | Not Available 4091.850 g/mol |  |
| Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha-subunits and irreversibly blocks the high conductance calci...more Number of Targets: 3 |
| T3D4278 | Deoxyadenosine triphosphate 1927-31-7 | C10H16N5O12P3 491.182 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2626 | alpha-Agatoxin 128549-96-2 | C26H47N7O2 489.697 g/mol |  |
| alpha-Agatoxins block the glutamate-activated receptor channels in the neuronal postsynaptic terminals of insects and mammals, preventing excitory junction potential f...more Number of Targets: 11 |
| T3D4430 | Deoxyuridine triphosphate 1173-82-6 | C9H15N2O14P3 468.142 g/mol |  |
| Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent of DNA damage caused by dUTP is dependent on the levels of the pyroph...more Number of Targets: 3 |
| T3D4962 | Galactosylsphingosine 2238-90-6 | C24H47NO7 461.633 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4281 | SAICAR 3031-95-6 | C13H19N4O12P 454.283 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2535 | Cinobufagin 470-37-1 | C26H34O6 442.545 g/mol |  |
| Cinobufagin blocks the sodium/potassium pump in heart tissue. (L1083, L1084) Number of Targets: 0 |
| T3D2489 | Philanthotoxin 77108-00-0 | C23H41N5O3 435.603 g/mol |  |
| Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016) Number of Targets: 9 |
| T3D2532 | Arenobufagin 464-74-4 | C24H32O6 416.507 g/mol |  |
| Arenobufagin blocks the sodium/potassium pump in heart tissue. (L1078) Number of Targets: 8 |
| T3D4038 | Gonyautoxin I 60748-39-2 | C10H17N7O9S 411.348 g/mol |  |
| The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more Number of Targets: 0 |
| T3D4343 | Cholic acid 81-25-4 | C24H40O5 408.571 g/mol |  |
| Not Available Number of Targets: 22 |
| T3D2536 | Marinobufagenin 470-42-8 | C24H32O5 400.508 g/mol |  |
| Marinobufagin blocks the sodium/potassium pump in heart tissue. (L1084, L1085) Number of Targets: 0 |
| T3D4456 | S-Adenosylmethionine 29908-03-0 | C15H23N6O5S 399.445 g/mol |  |
| S-Adenosylmethionine (SAMe) is a natural substance present in the cells of the body. It is a direct metabolite of the essential amino acid L-methionine. SAMe plays a c...more Number of Targets: 10 |
| T3D4286 | Hexacosanoic acid 506-46-7 | C26H52O2 396.690 g/mol |  |
| Adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a gene located on the X chromosome that codes for ALD, a peroxisomal membrane transporter protein. The exac...more Number of Targets: 0 |
| T3D4039 | Gonyautoxin II 60508-89-6 | C10H17N7O8S 395.349 g/mol |  |
| The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more Number of Targets: 0 |
| T3D4961 | Deoxycholic acid 83-44-3 | C24H40O4 392.572 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4314 | Cholesterol 57-88-5 | C27H46O 386.654 g/mol |  |
| Cholesterol is essential for life. However, chronically high levels (from diet or from genetic predisposition or from diseases such as hyperlipidemia) of cholesterol a...more Number of Targets: 12 |
| T3D4455 | S-Adenosylhomocysteine 979-92-0 | C14H20N6O5S 384.411 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D4963 | Lithocholic acid 434-13-9 | C24H40O3 376.573 g/mol |  |
| Not Available Number of Targets: 11 |