Browsing Toxins By Category
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4030 | Dinophysistoxin 1 81720-10-7 | C45H70O13 819.030 g/mol |
| Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more Number of Targets: 0 | |
T3D4029 | Okadaic acid 78111-17-8 | C44H68O13 805.003 g/mol |
| Okadaic acid (OA) dramatically increases both nerve growth factor (NGF) mRNA content (50-fold) and NGF secretion (100-fold) in astrocytes. Okadaic acid also activated ...more Number of Targets: 1 | |
T3D4023 | Neosaxitoxin 64296-20-4 | C10H17N7O5 315.286 g/mol |
| Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated sodium channels in a very powerful and reversible manner, without affe...more Number of Targets: 0 | |
T3D3973 | Monoethylhexyl phthalic acid 4376-20-9 | C16H22O4 278.344 g/mol |
| Not Available Number of Targets: 7 | |
T3D3971 | 1-Hydroxypyrene 5315-79-7 | C16H12O 220.266 g/mol |
| Not Available Number of Targets: 15 | |
T3D3968 | 1-Naphthol 90-15-3 | C10H8O 144.170 g/mol |
| 1-Naphthol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 5 | |
T3D3967 | Enterolactone 76543-15-2 | C18H18O4 298.333 g/mol |
| Not Available Number of Targets: 3 | |
T3D3965 | O-Desmethylangolensin 21255-69-6 | C15H14O4 258.269 g/mol |
| O-desmethylangolensin (ODMA) exerts androgen receptor antagonistic activity and agonistic activity towards estrogen receptor (ER)-α and ERβ. The structure of ODMA is s...more Number of Targets: 2 | |
T3D3962 | Equol 531-95-3 | C15H14O3 242.270 g/mol |
| Not Available Number of Targets: 2 | |
T3D3961 | Monoethyl phthalate 2306-33-4 | C10H10O4 194.184 g/mol |
| Not Available Number of Targets: 3 | |
T3D3960 | Monoisobutyl phthalic acid 30833-53-5 | C12H14O4 222.237 g/mol |
| Phthalates are synthetic industrial compounds capable of disrupting the endocrine system. The phthalates have been the most common chemical compounds with the ability ...more Number of Targets: 4 | |
T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 | |
T3D3956 | Cotinine 486-56-6 | C10H12N2O 176.215 g/mol |
| Not Available Number of Targets: 1 | |
T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 | |
T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 | |
T3D3233 | CE(10:0) 1183-04-6 | C37H64O2 540.903 g/mol |
| Not Available Number of Targets: 2 | |
T3D2972 | Melatonin 73-31-4 | C13H16N2O2 232.278 g/mol |
| Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts on adenylate cylcase and the inhibition of a cAMP signal transduction ...more Number of Targets: 18 | |
T3D2702 | (R)-lipoic acid 62-46-4 | C8H14O2S2 206.326 g/mol |
| (R)-lipoic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholi...more Number of Targets: 6 | |
T3D2690 | Biotin 58-85-5 | C10H16N2O3S 244.311 g/mol |
| Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, includ...more Number of Targets: 10 | |
T3D2672 | Azaspiracid 214899-21-5 | C47H71NO12 842.066 g/mol |
| Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more Number of Targets: 1 | |
T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 | |
T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 | |
T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 | |
T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 | |
T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 |