Search Results for compounds

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … 3-Hydroxypropionic acid is a carboxylic acid. It is used in the production of various chemicals …
Matched name: … Hydroxypropionic acid …
Matched synonyms: … Hydroxypropionic acid ... 2-Deoxyglyceric acid ... 3-Hydroxypropanoic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine ... , depends only on presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are ... physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the …
Matched name: … Cholic acid …
Matched synonyms: … Cholic acid ... 3a,7a,12a-Trihydroxy-5b-cholan-24-oic acid ... 3a,7a,12a-Trihydroxy-5b-cholanic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … , signalling, apoptotic and lipolytic functions Okadaic acid belongs to the family of Okadaic Acids ... and Halichondria melanodocia and shellfish. It is a metabolite of Prorocentrum lima. It is a ... diarrhetic shellfish toxin. Okadaic acid is a toxin that accumulates in bivalves and causes diarrhetic …
Matched name: … Okadaic acid …
Matched synonyms: … Okadaic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … 4-Hydroxybutyric acid (GHB) is a precursor and a metabolite of gamma-aminobutyric acid (GABA), it ... through GABA and GHB-specific receptors, or by affecting dopamine transmission. Gamma-hydroxybutyric ... acid (GHB) occurs naturally in all. mammals, but its function remains unknown. GHB is a therapeutic …
Matched name: … 4-Hydroxybutyric acid …
Matched synonyms: … 4-Hydroxybutyric acid ... 3-carboxypropoxy acid ... 4-Hydroxy-Butanoic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment may include washing any areas of contact, GI decontamination if swallowed, administering an IV and forced alkaline diuresis. (L346) …
Matched description: … 4-(4-Chloro-2-methylphenoxy)butanoic acid (MCPB, 2,4-MCPB) is a phenoxybutyric herbicide. In the ... United States it is registered for use on pea crops before flowering, for post-emergence control of ... broadleaf annual and perennial weeds including Canadian thistle, buttercup, mustard, purslane, ragweed …
Matched name: … 4-(4-Chloro-2-methylphenoxy)butanoic acid …
Matched synonyms: … 4-(4-Chloro-2-methylphenoxy)butanoic acid ... (2-Methyl-4-chlorophenoxy)butyric acid ... (4-chloro-2-Methylphenoxy)butyric acid …

Matched symptoms: … Acute Exposure: the clinical signs of acute toxicity are weakness and diarrhea. …
Matched carcinogenicity: … Not listed by IARC. Has been implicated in oncogenesis (A15088). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Succinic acid is a dicarboxylic acid. The anion, succinate, is a component of the citric acid cycle ... capable of donating electrons to the electron transfer chain. Succinic acid is created as a ... byproduct of the fermentation of sugar. It lends to fermented beverages such as wine and beer a common …
Matched name: … Succinic acid …
Matched synonyms: … Succinic acid ... 1,2-Ethanedicarboxylic acid ... 1,4-Butanedioic acid …

Matched symptoms: … Skin contact can cause redness, pain, and severe skin burns. Chromic acid may cause severe burns to ... the eye and permanent eye damage. Severe and rapid corrosive burns of the mouth, gullet and ... gastrointestinal tract will result if chromic acid is swallowed. Symptoms include burning, choking, nausea, vomiting and severe pain. …
Matched treatment: … The mainstay of treatment of any acid burn is copious irrigation with large amounts of tap water ... arrival in the emergency department. Remove any contaminated clothing. Do not attempt to neutralize the ... burn with weak reciprocal chemicals (i.e. alkali for acid burns), because the heat generated from the chemical reaction may cause severe thermal injury. …
Matched description: … Chromic acid generally refers to a collection of compounds generated by the acidification of ... solutions containing chromate and dichromate anions or the dissolving of chromium trioxide in sulfuric ... oxidation state, and is more toxic than other oxidation states of the chromium atom because of its …
Matched name: … Chromic acid …
Matched synonyms: … Chromic acid ... Chromic Acid ... Tetraoxochromic acid …

Matched symptoms: … Acute exposure to fumaric acid can cause eye and skin irritation, cough or sore throat (inhalation), abdominal cramps, nausea and diarrhea (ingestion). …
Matched carcinogenicity: … Not listed by IARC. Has been implicated in oncogenesis (A15088, A15092). …
Matched treatment: … care is possible. For cancers caused by intracellular fumarate excess, there are a wide variety of cancer treatments including drugs and surgery. ... not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If …
Matched description: … taste of wine. Fumaric acid can also be added to dairy products, sports drinks, jams, jellies and ... fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid. Fumarate has ... cake mixes and flours, as well as tortillas. Fumaric acid is also added to bread to increase the …
Matched name: … Fumaric acid …
Matched synonyms: … Fumaric acid ... (2E)-But-2-enedioic acid ... (E)-2-Butenedioic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … foci could cause spontaneous opening of voltage activated calcium channels, leading to glutamic acid release and further depolarization. ... Glutamic acid (Glu), also referred to as glutamate (the anion), is one of the 20 proteinogenic ... of its role in synaptic plasticity, it is believed that glutamic acid is involved in cognitive …
Matched name: … L-Glutamic acid …
Matched synonyms: … L-Glutamic acid ... (2S)-2-Aminopentanedioic acid ... (S)-(+)-Glutamic acid …
Matched compound_type: … Non-Essential Amino Acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … In chemistry, the anion, the salts, and the esters of pyrophosphoric acid are called pyrophosphates ... . The anion is abbreviated PPi and is formed by the hydrolysis of ATP into AMP in cells. This ... hydrolysis is called pyrophosphorolysis. The pyrophosphate anion has the structure P2O74-, and is an acid …
Matched synonyms: … (4-)Diphosphoric acid ion ... Diphosphoric acid ... Pyrophosphic acid …

Matched symptoms: … calcium following substantial overdosage may be expected in some patients. Signs and symptoms of ... etidronate was reported to be mildly hypocalcemic (7 .5 2 mg/ dl) and experienced paresthesia of the fingers. ... Clinical experience with acute etidronic acid overdosage is extremely limited. Decreases in serum …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … and inhibit the formation and dissolution of the crystals. Other actions may include direct ... inhibition of mature osteoclast function, promotion of osteoclast apoptosis, and interference with osteoblast ... -mediated osteoclast activation. Etidronic acid does not interfere with bone mineralization. In …
Matched name: … Etidronic acid …
Matched synonyms: … Etidronic acid ... (1-Hydroxyethylene)diphosphonic acid ... (1-Hydroxyethylidene)bis(phosphonic acid) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … defective cleavage of ASA. This leads to an accumulation of ASA in cells and an excessive excretion of ... of ASA lyase deficiency include anorexia, irritability rapid breathing, lethargy and vomiting. Extreme symptoms include coma and cerebral edema. ... Arginosuccinic acid is a basic amino acid. Some cells synthesize it from citrulline, aspartic acid …
Matched name: … Argininosuccinic acid …
Matched synonyms: … Argininosuccinic acid ... 2-(N(Omega)-L-arginine)succinic acid ... 2-(N(Omega)-L-arginino)succinic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … of the subunits in ferritin, astacin, and other 'buffer' proteins. Leucine is an essential amino ... acid, meaning that the human body cannot synthesize it, and it therefore must be ingested. It is important for hemoglobin formation. ... Leucine (abbreviated as Leu or L)[2] is a branched-chain л±-amino acid with the chemical …
Matched synonyms: … (2S)-2-Amino-4-methylpentanoic acid ... (2S)-alpha-2-Amino-4-methylvaleric acid ... (S)-2-Amino-4-methylpentanoic acid …
Matched compound_type: … Amino Acid, Essential …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … both by contact or oral ingestion; they are relatively safe to vertebrates and degrade rapidly in the environment. (T10) …
Matched name: … 3-[(2E)-2-(Nitromethylidene)hydrazinyl]benzoic acid …
Matched synonyms: … 3-[(2E)-2-(Nitromethylidene)hydrazinyl]benzoic acid ... 3-[(2e)-2-(Nitromethylene)hydrazino]benzoic acid ... 3-[(2e)-2-(Nitromethylidene)hydrazinyl]benzoic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of ... , 3-Methylcrotonyl-CoA carboxylase 2 deficiency. 3-Hydroxyisovaleric acid is also elevated in smokers ... , in subjects undergoing long-term anticonvulsant therapy with carbamazepine and/or phenytoin. These …
Matched name: … 3-Hydroxyisovaleric acid …
Matched synonyms: … 3-Hydroxyisovaleric acid ... 3-Hydroxy-3-methyl-Butanoic acid ... 3-Hydroxy-3-methyl-Butyric acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate ... pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. It is highly concentrated in ... muscle and is one of the most important amino acids released by muscle, functioning as a major …
Matched synonyms: … (2S)-2-Aminopropanoic acid ... (S)-2-amino-Propanoic acid ... (S)-2-Aminopropanoic acid …
Matched compound_type: … Non-Essential Amino Acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are ... mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is …
Matched synonyms: … 5-Ethyl-5-(3-methylbutyl)barbituric acid ... 5-Ethyl-5-isoamylbarbituric acid ... 5-Ethyl-5-isopentylbarbituric acid …

Matched symptoms: … Chronic exposure of high levels of L-2-hydroxyglutarate leads to hypotonia, tremors, and epilepsy ... declining into spongiform leukoencephalopathy, muscular choreodystonia, mental retardation, and psychomotor regression. …
Matched carcinogenicity: … Not listed by IARC. Has been implicated in oncogenesis (A15091, A15090). …
Matched description: … -2-hydroxyglutaric aciduria. Both the D and the L stereoisomers of hydroxyglutaric acid (EC 1.1.99.2 ... compound can be converted to α-ketoglutaric acid through the action of a 2-hydroxyglutarate dehydrogenase ... . In humans, there are two such enzymes called D2HGDH and L2HGDH. Tissue accumulation of high …
Matched name: … L-2-Hydroxyglutaric acid …
Matched synonyms: … L-2-Hydroxyglutaric acid ... (S)-2-Hydroxyglutaric acid ... (S)-a-Hydroxyglutaric acid …

Matched symptoms: … Oxalic acid poisoning symptoms include weakness, burning in the mouth, death from cardiovascular ... collapse, on the respiratory system, throat – burning in the throat, abdominal pain, nausea, vomiting, diarrhea, convulsions, and coma. …
Matched carcinogenicity: … No indication of carcinogenicity (not listed by IARC). (L135) …
Matched treatment: … Acute Exposure: If oxalic acid is swallowed, immediately give the person water or milk, unless ... instructed otherwise by a health care provider. DO NOT give water or milk if the person is having ... symptoms (such as vomiting, convulsions, or a decreased level of alertness) that make it hard to swallow …
Matched description: … growth. However, oxalic acid is not particularly safe and is considered a mild toxin. In ... give colorless, acidic solutions. In terms of acid strength, it is much stronger than acetic acid ... . Oxalic acid, because of its di-acid structure can also act as a chelating agent for metal cations …
Matched name: … Oxalic acid …
Matched synonyms: … Oxalic acid ... Ethane-1,2-dioic acid ... Ethanedioic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Methylmalonic acid is a malonic acid derivative which is a vital intermediate in the metabolism of ... fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This ... metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. …
Matched name: … Methylmalonic acid …
Matched synonyms: … Methylmalonic acid ... 1,1-Ethanedicarboxylic acid ... 2-Methylmalonic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Diethylphosphate is product of metabolism and of environmental degradation of Chlorpyrifos (CPF; a ... commonly used diethylphosphorothionate organophosphorus (OP) insecticide) and are routinely measured in urine as biomarkers of exposure. (A3200). …
Matched synonyms: … Diethyl acid phosphate ... Diethyl phosphoric acid ... Diethylphosphic acid …

Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched description: … Penicillic acid is a mycotoxin produced by several species of Aspergillus and Penicillium. It has ... antibiotic activity and is cytotoxic, hepatotoxic, and carcinogenic. Penicillic acid is a human …
Matched name: … Penicillic acid …
Matched synonyms: … Penicillic acid ... 3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid ... 3-Methoxy-5-methyl-4-oxohexa-2,5-dienoic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Clopyralid-olamine is a picolinic acid herbicide belonging to the general class of pyridine ... herbicides. It is a derivative of clopyralid. It is used as a selective systemic herbicide, absorbed by the ... leaves and roots, with translocation both acropetally and basipetally, and accumulation in …
Matched synonyms: … 3,6-Dichloro-2-pyridinecarboxylic acid - 2-aminoethanol (1:1) ... 3,6-Dichloropyridine-2-carboxylic acid ethanolamine salt ... 3,6-dichloropyridine-2-carboxylic acid, 2-aminoethan-1-ol …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … that the presence of this acid is from nutritional sources (i.e. dietary phenylalanine). However, there ... has been a considerable degree of ambiguity in the origin and/or significance of this compound ... (3-Hydroxyphenyl)hydracrylate (HPHPA) is an organic acid detected in human urine. It is thought …
Matched name: … 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid …
Matched synonyms: … 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid ... (3-Hydroxyphenyl)hydracrylic acid ... 3'-Hydroxyphenylhydracrylic acid …

Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched description: … Kojic acid is a synthetic intermediate for production of food additives. Kojic acid has been shown to exhibit anti-neoplastic function (A7859). …
Matched name: … Kojic acid …
Matched synonyms: … Kojic acid …