Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4257 | Oxoadipic acid 3184-35-8 | C6H8O5 160.125 g/mol |  |
| In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. Accumulation ...more Number of Targets: 1 |
| T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |  |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 |
| T3D4259 | Aminoadipic acid 542-32-5 | C6H11NO4 161.156 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4262 | 3-Hydroxymethylglutaric acid 503-49-1 | C6H10O5 162.141 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4263 | 3-Hydroxyisovaleric acid 625-08-1 | C5H10O3 118.131 g/mol |  |
| 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several disorders due to impairment of renal...more Number of Targets: 0 |
| T3D4265 | 3-Methylglutaconic acid 5746-90-7 | C6H8O4 144.125 g/mol |  |
| Accumulation of 3-methylglutaconic acid in the body has been shown to be toxic. 3-methylglutaconyl-CoA hydratase is involved in the metabolism process of 3-methylgluta...more Number of Targets: 0 |
| T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |  |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 |
| T3D4270 | Pyroglutamic acid 98-79-3 | C5H7NO3 129.114 g/mol |  |
| 5-Oxoprolinuria develops in moderate to severe cases of glutathione synthetase deficiency. The deficiency in glutathione synthetase leads to the accumulation of γ-glut...more Number of Targets: 12 |
| T3D4273 | 5-Aminolevulinic acid 106-60-5 | C5H9NO3 131.130 g/mol |  |
| According to the presumed mechanism of action, photosensitization following application of aminolevulinic acid (ALA) topical solution occurs through the metabolic conv...more Number of Targets: 3 |
| T3D4274 | Porphobilinogen 487-90-1 | C10H14N2O4 226.229 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4275 | Adenosine 58-61-7 | C10H13N5O4 267.241 g/mol |  |
| Adenosine slows conduction time through the AV node and can interrupt the reentry pathways through the AV node, resulting in the restoration of normal sinus rhythm in ...more Number of Targets: 11 |
| T3D4276 | Adenosine triphosphate 56-65-5 | C10H16N5O13P3 507.181 g/mol |  |
| ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cel...more Number of Targets: 42 |
| T3D4278 | Deoxyadenosine triphosphate 1927-31-7 | C10H16N5O12P3 491.182 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4279 | Adenine 73-24-5 | C5H5N5 135.127 g/mol |  |
| Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotid...more Number of Targets: 10 |
| T3D4281 | SAICAR 3031-95-6 | C13H19N4O12P 454.283 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4282 | 17-Hydroxyprogesterone 68-96-2 | C21H30O3 330.461 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4283 | Testosterone 58-22-0 | C19H28O2 288.424 g/mol |  |
| Testosterone is considered an anabolic steroid. It plays a key role in the development of male reproductive tissues such as the testis and prostate as well as promotin...more Number of Targets: 10 |
| T3D4284 | 18-Hydroxycorticosterone 561-65-9 | C21H30O5 362.460 g/mol |  |
| 18-Hydroxycorticosterone is a derivative of corticosterone. It serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona...more Number of Targets: 1 |
| T3D4286 | Hexacosanoic acid 506-46-7 | C26H52O2 396.690 g/mol |  |
| Adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a gene located on the X chromosome that codes for ALD, a peroxisomal membrane transporter protein. The exac...more Number of Targets: 0 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |
| T3D4289 | L-Arginine 74-79-3 | C6H14N4O2 174.201 g/mol |  |
| Many of supplemental L-arginine's activities, including its possible anti-atherogenic actions, may be accounted for by its role as the precursor to nitric oxide or NO....more Number of Targets: 9 |
| T3D4290 | Creatine 57-00-1 | C4H9N3O2 131.133 g/mol |  |
| In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosp...more Number of Targets: 7 |
| T3D4292 | Orotic acid 65-86-1 | C5H4N2O4 156.096 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4294 | Argininosuccinic acid 2387-71-5 | C10H18N4O6 290.273 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4295 | Citrulline 372-75-8 | C6H13N3O3 175.186 g/mol |  |
| L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's act...more Number of Targets: 13 |