Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2581 | Hongotoxin 203526-59-4 | Not Available 4226.080 g/mol |  |
| Hongotoxin inhibits voltage-gated potassium channels. (L1049) Number of Targets: 4 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |
| T3D2492 | Holocyclotoxin 88254-04-0 | Not Available 7834.125 g/mol |  |
| Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) Number of Targets: 0 |
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D4286 | Hexacosanoic acid 506-46-7 | C26H52O2 396.690 g/mol |  |
| Adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a gene located on the X chromosome that codes for ALD, a peroxisomal membrane transporter protein. The exac...more Number of Targets: 0 |
| T3D2631 | Heteroscodratoxin Not Available | Not Available 4003.400 g/mol |  |
| Heteroscodratoxin inhibits voltage-gated potassium channels by binding to the extracellular linker of the channel and shifting activation of the channel to more depola...more Number of Targets: 5 |
| T3D2505 | Heteropodatoxin 189120-72-7 | Not Available 3917.380 g/mol |  |
| Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating modifier. As a result, a larger depolarization is needed to open the ch...more Number of Targets: 3 |
| T3D2566 | Heparin 9005-49-6 | C26H41NO34S4 1039.850 g/mol |  |
| Heparin-induced thrombocytopenia (HIT) is caused by the formation of abnormal antibodies that activate platelets. Heparin occurs naturally in the human body, but the d...more Number of Targets: 14 |
| T3D4372 | Hawkinsin 63224-90-8 | C11H17NO6S 291.321 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2629 | Hanatoxin 170780-01-5 | Not Available 4120.690 g/mol |  |
| Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it does by occupying multiple binding sites on the channel. It can also in...more Number of Targets: 3 |
| T3D4051 | Gymnodimine 173792-58-0 | C32H45NO4 507.704 g/mol |  |
| Gymnodimine exerts its toxic effects via binding to nicotinic acetylcholine receptors with picomolar affinities with no sign of apparent reversibility in short time fr...more Number of Targets: 0 |
| T3D2498 | Grammotoxin 152617-90-8 | Not Available 9600.980 g/mol |  |
| Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more Number of Targets: 3 |
| T3D4039 | Gonyautoxin II 60508-89-6 | C10H17N7O8S 395.349 g/mol |  |
| The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more Number of Targets: 0 |
| T3D4038 | Gonyautoxin I 60748-39-2 | C10H17N7O9S 411.348 g/mol |  |
| The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more Number of Targets: 0 |
| T3D4442 | Glyoxylic acid 298-12-4 | C2H2O3 74.036 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4318 | Glycine 56-40-6 | C2H5NO2 75.067 g/mol |  |
| In the CNS, there exist strychnine-sensitive glycine binding sites as well as strychnine-insensitive glycine binding sites. The strychnine-insensitive glycine-binding ...more Number of Targets: 31 |
| T3D4360 | Glycerol 56-81-5 | C3H8O3 92.094 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D4330 | Glyceric acid 473-81-4 | C3H6O4 106.077 g/mol |  |
| Glyceric acid is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria and D-glycerate anemia. Deficiency of human glycer...more Number of Targets: 1 |
| T3D4964 | Glyceraldehyde 56-82-6 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4352 | Glutathione 70-18-8 | C10H17N3O6S 307.323 g/mol |  |
| Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is...more Number of Targets: 42 |
| T3D4359 | Glutaric acid 110-94-1 | C5H8O4 132.115 g/mol |  |
| Accumulation of glutaric acid in the body has been shown to be toxic. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutar...more Number of Targets: 1 |
| T3D4358 | Glutaconic acid 1724-02-3 | C5H6O4 130.099 g/mol |  |
| Accumulating trans-glutaconic (TG) acids has been proposed to be involved in the development of the striatal degeneration seen in children with glutaric acidemia type ...more Number of Targets: 1 |
| T3D4250 | Gamma-Aminobutyric acid 56-12-2 | C4H9NO2 103.120 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D4962 | Galactosylsphingosine 2238-90-6 | C24H47NO7 461.633 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4960 | Galactonic acid 13382-27-9 | C6H12O7 196.155 g/mol |  |
| Not Available Number of Targets: 0 |