Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4296 | L-Glutamic acid 56-86-0 | C5H9NO4 147.129 g/mol |  |
| Glutamate activates both ionotropic and metabotropic glutamate receptors. The ionotropic ones being non-NMDA (AMPA and kainate) and NMDA receptors. Free glutamic acid ...more Number of Targets: 76 |
| T3D4298 | 5-Hydroxy-L-tryptophan 4350-09-8 | C11H12N2O3 220.225 g/mol |  |
| 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. An accumulation of 5-hydroxy-L-tryptophan in cerebrospinal fluid occurs in aromati...more Number of Targets: 1 |
| T3D4300 | Dopamine 51-61-6 | C8H11NO2 153.178 g/mol |  |
| Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces posi...more Number of Targets: 15 |
| T3D4304 | Hydroxypropionic acid 503-66-2 | C3H6O3 90.078 g/mol |  |
| 3-hydroxypropionic acid (3HP) toxicity is mediated by 3-hydroxypropionic aldehyde (reuterin). 3HP toxicity is also proposed to be related to inhibition of the chorisma...more Number of Targets: 0 |
| T3D4307 | D-Lactic acid 10326-41-7 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4310 | N-Acetyl-L-aspartic acid 997-55-7 | C6H9NO5 175.139 g/mol |  |
| The primary proposed functions of N-acetylaspartic acid include: 1) A neuronal osmolyte that is involved in fluid balance in the brain; 2) a source of acetate for lipi...more Number of Targets: 0 |
| T3D4314 | Cholesterol 57-88-5 | C27H46O 386.654 g/mol |  |
| Cholesterol is essential for life. However, chronically high levels (from diet or from genetic predisposition or from diseases such as hyperlipidemia) of cholesterol a...more Number of Targets: 12 |
| T3D4318 | Glycine 56-40-6 | C2H5NO2 75.067 g/mol |  |
| In the CNS, there exist strychnine-sensitive glycine binding sites as well as strychnine-insensitive glycine binding sites. The strychnine-insensitive glycine-binding ...more Number of Targets: 31 |
| T3D4319 | L-Glutamine 56-85-9 | C5H10N2O3 146.145 g/mol |  |
| Supplemental L-glutamine's possible immunomodulatory role may be accounted for in a number of ways. L-glutamine appears to play a major role in protecting the integrit...more Number of Targets: 3 |
| T3D4320 | L-Alanine 56-41-7 | C3H7NO2 89.093 g/mol |  |
| L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar...more Number of Targets: 13 |
| T3D4322 | Uroporphyrin III 18273-06-8 | C40H38N4O16 830.747 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4323 | Coproporphyrin III 14643-66-4 | C36H38N4O8 654.709 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4324 | Uroporphyrin I 607-14-7 | C40H38N4O16 830.747 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4325 | Pyruvic acid 127-17-3 | C3H4O3 88.062 g/mol |  |
| Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more Number of Targets: 16 |
| T3D4328 | L-Methionine 63-68-3 | C5H11NO2S 149.211 g/mol |  |
| The mechanism of the possible anti-hepatotoxic activity of L-methionine is not entirely clear. It is thought that metabolism of high doses of acetaminophen in the live...more Number of Targets: 5 |
| T3D4330 | Glyceric acid 473-81-4 | C3H6O4 106.077 g/mol |  |
| Glyceric acid is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria and D-glycerate anemia. Deficiency of human glycer...more Number of Targets: 1 |
| T3D4332 | Dihydrothymine 696-04-8 | C5H8N2O2 128.129 g/mol |  |
| Dihydropyrimidine dehydrogenase catalyzes the reduction of thymine to 5, 6-dihydrothymine then dihydropyrimidinase hydrolyzes 5, 6-dihydrothymine to N-carbamyl-b-alani...more Number of Targets: 0 |
| T3D4333 | Dihydrouracil 504-07-4 | C4H6N2O2 114.103 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4343 | Cholic acid 81-25-4 | C24H40O5 408.571 g/mol |  |
| Not Available Number of Targets: 22 |
| T3D4344 | Potassium 7440-09-7 | K 39.098 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4345 | D-Fructose 53188-23-1 | C6H12O6 180.156 g/mol |  |
| Fructose is distinct from other sugars in its ability to cause intracellular ATP depletion, nucleotide turnover, and the generation of uric acid. Uric acid is generate...more Number of Targets: 5 |
| T3D4346 | Beta-Alanine 107-95-9 | C3H7NO2 89.093 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4350 | Bilirubin 635-65-4 | C33H36N4O6 584.662 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4352 | Glutathione 70-18-8 | C10H17N3O6S 307.323 g/mol |  |
| Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is...more Number of Targets: 42 |
| T3D4356 | D-Glucose 50-99-7 | C6H12O6 180.156 g/mol |  |
| Very high serum levels of glucose are found in untreated diabetic (type I or type II) patients. Glucose in chronic excess causes toxic effects on the structure and fun...more Number of Targets: 33 |