Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2628 | kappa-Atracotoxin (Hadronyche versuta) Not Available | Not Available 3685.155 g/mol |  |
| kappa-Atracotoxins inhibit insect voltage-gated potassium channels. (T170, L1812) Number of Targets: 0 |
| T3D2629 | Hanatoxin 170780-01-5 | Not Available 4120.690 g/mol |  |
| Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it does by occupying multiple binding sites on the channel. It can also in...more Number of Targets: 3 |
| T3D2630 | Sphingomyelinase D (Loxosceles intermedia) 9031-54-3 | Not Available 34158.125 g/mol |  |
| Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemolysis, dermonecrosis, blood vessel permeability and platelet aggregati...more Number of Targets: 0 |
| T3D2631 | Heteroscodratoxin Not Available | Not Available 4003.400 g/mol |  |
| Heteroscodratoxin inhibits voltage-gated potassium channels by binding to the extracellular linker of the channel and shifting activation of the channel to more depola...more Number of Targets: 5 |
| T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |  |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 |
| T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |  |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 |
| T3D4726 | Alteplase 105857-23-6 | Not Available 62916.495 g/mol |  |
| Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen ...more Number of Targets: 4 |
| T3D4344 | Potassium 7440-09-7 | K 39.098 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4405 | Calcium 7440-70-2 | Ca 40.077 g/mol |  |
| Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human ...more Number of Targets: 17 |
| T3D4202 | Carbamic acid 463-77-4 | CH3NO2 61.040 g/mol |  |
| Carbamic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholine...more Number of Targets: 1 |
| T3D4769 | Ethanolamine 141-43-5 | C2H7NO 61.083 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4214 | Diethylamine 71247-25-1 | C4H11N 73.137 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4442 | Glyoxylic acid 298-12-4 | C2H2O3 74.036 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4444 | Propionic acid 79-09-4 | C3H6O2 74.079 g/mol |  |
| In healthy individuals, the enzyme propionyl CoA carboxylase converts propionyl CoA to methylmalonyl CoA. This is one step in the process of converting certain amino a...more Number of Targets: 2 |
| T3D4318 | Glycine 56-40-6 | C2H5NO2 75.067 g/mol |  |
| In the CNS, there exist strychnine-sensitive glycine binding sites as well as strychnine-insensitive glycine binding sites. The strychnine-insensitive glycine-binding ...more Number of Targets: 31 |
| T3D4971 | Bromide ion 24959-67-9 | Br 79.905 g/mol |  |
| The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in ...more Number of Targets: 23 |
| T3D4466 | Sulfite 14265-45-3 | O3S 80.064 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |  |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D4325 | Pyruvic acid 127-17-3 | C3H4O3 88.062 g/mol |  |
| Pyruvate serves as a biological fuel by being converted to acetyl coenzyme A, which enters the tricarboxylic acid or Krebs cycle where it is metabolized to produce ATP...more Number of Targets: 16 |
| T3D4592 | Butyric acid 107-92-6 | C4H8O2 88.105 g/mol |  |
| Butyric acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 10 |
| T3D4346 | Beta-Alanine 107-95-9 | C3H7NO2 89.093 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4320 | L-Alanine 56-41-7 | C3H7NO2 89.093 g/mol |  |
| L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar...more Number of Targets: 13 |
| T3D4458 | Sarcosine 107-97-1 | C3H7NO2 89.093 g/mol |  |
| Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent oncoprotein called human epidermal growth factor receptor 2 (HER2/neu) in ...more Number of Targets: 2 |
| T3D4307 | D-Lactic acid 10326-41-7 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4253 | L-Lactic acid 79-33-4 | C3H6O3 90.078 g/mol |  |
| Accumulation of L-lactic acid in the body has been shown to be toxic. At times of lactic acidosis, when excess intracellular lactate is released into the blood, mainte...more Number of Targets: 1 |