Browsing Toxins
Displaying toxin 3201 - 3225 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4362 | L-Asparagine 70-47-3 | C4H8N2O3 132.118 g/mol |  |
| Asparagine, a non-essential amino acid is important in the metabolism of toxic ammonia in the body through the action of asparagine synthase which attaches ammonia to ...more Number of Targets: 6 |
| T3D4363 | L-Histidine 71-00-1 | C6H9N3O2 155.155 g/mol |  |
| Since the actions of supplemental L-histidine are unclear, any postulated mechanism is entirely speculative. However, some facts are known about L-histidine and some o...more Number of Targets: 5 |
| T3D4364 | L-Isoleucine 73-32-5 | C6H13NO2 131.173 g/mol |  |
| (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of ca...more Number of Targets: 6 |
| T3D4365 | L-Leucine 61-90-5 | C6H13NO2 131.173 g/mol |  |
| This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of carbon atoms cannot be made by humans, these a...more Number of Targets: 10 |
| T3D4366 | L-Phenylalanine 63-91-2 | C9H11NO2 165.189 g/mol |  |
| Extremely high serum levels of phenylalanine are found in patients with the inborn error of metabolism (IEM) called Phenylketonuria (PKU). At pathological concentratio...more Number of Targets: 10 |
| T3D4367 | L-Serine 56-45-1 | C3H7NO3 105.093 g/mol |  |
| L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the ...more Number of Targets: 8 |
| T3D4368 | L-Threonine 72-19-5 | C4H9NO3 119.119 g/mol |  |
| L-Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in controlling fat build-up in the liver. May help combat mental illness and ...more Number of Targets: 3 |
| T3D4369 | L-Tryptophan 73-22-3 | C11H12N2O2 204.225 g/mol |  |
| A number of important side reactions occur during the catabolism of tryptophan on the pathway to acetoacetate. The first enzyme of the catabolic pathway is an iron por...more Number of Targets: 7 |
| T3D4370 | L-Valine 72-18-4 | C5H11NO2 117.146 g/mol |  |
| (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of ca...more Number of Targets: 3 |
| T3D4371 | L-Tyrosine 60-18-4 | C9H11NO3 181.189 g/mol |  |
| Tyrosine is produced in cells by hydroxylating the essential amino acid phenylalanine. This relationship is much like that between cysteine and methionine. Half of the...more Number of Targets: 5 |
| T3D4372 | Hawkinsin 63224-90-8 | C11H17NO6S 291.321 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4398 | Saccharopine 997-68-2 | C11H20N2O6 276.286 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4404 | Methylmalonic acid 516-05-2 | C4H6O4 118.088 g/mol |  |
| Methylmalonic acid is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This me...more Number of Targets: 0 |
| T3D4405 | Calcium 7440-70-2 | Ca 40.077 g/mol |  |
| Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human ...more Number of Targets: 17 |
| T3D4409 | Xanthine 69-89-6 | C5H4N4O2 152.111 g/mol |  |
| Xanthine is a poorly soluble compound. As a result high concentrations of serum xanthine can lead to the formation of kidney stones (xanthine kidney stones) which can...more Number of Targets: 0 |
| T3D4411 | L-Proline 147-85-3 | C5H9NO2 115.131 g/mol |  |
| Glycogenic, by L-Proline oxidase in the kidney, it is ring-opened and is oxidized to form L-Glutamic acid. L-Ornithine and L-Glutamic acid are converted to L-Proline v...more Number of Targets: 23 |
| T3D4413 | 4-Hydroxyproline 51-35-4 | C5H9NO3 131.130 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4424 | 3-Methyl-2-oxovaleric acid 1460-34-0 | C6H10O3 130.142 g/mol |  |
| 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1, whereupon it is further degraded by branched chain keto acid deh...more Number of Targets: 0 |
| T3D4425 | Alpha-ketoisovaleric acid 759-05-7 | C5H8O3 116.115 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4426 | Ketoleucine 816-66-0 | C6H10O3 130.142 g/mol |  |
| Ketoleucine is a metabolite that accumulates in Maple Syrup Urine Disease (MSUD) and shown to compromise brain energy metabolism by blocking the respiratory chain. Number of Targets: 0 |
| T3D4430 | Deoxyuridine triphosphate 1173-82-6 | C9H15N2O14P3 468.142 g/mol |  |
| Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent of DNA damage caused by dUTP is dependent on the levels of the pyroph...more Number of Targets: 3 |
| T3D4434 | S-Sulfocysteine 1637-71-4 | C3H6NO5S2 200.214 g/mol |  |
| S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have shown that SSC displays depolarizing properties similar to glutamate. S...more Number of Targets: 3 |
| T3D4435 | Tyramine 51-67-2 | C8H11NO 137.179 g/mol |  |
| Tyramine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D4438 | Coproporphyrinogen III 2624-63-7 | C36H44N4O8 660.757 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4439 | Protoporphyrinogen IX 7412-77-3 | C34H40N4O4 568.706 g/mol |  |
| Not Available Number of Targets: 0 |