Tmic
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Displaying toxins 176 - 200 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D0215Chromic acid
7738-94-5
CrH2O4
118.010 g/mol
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  • Chromium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Chromic acid is highly corrosive and strongly oxidative. Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysis of proteins....more
Number of Targets: 5
T3D0216Nitrate
14797-55-8
NO3
62.005 g/mol
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  • Food Toxin
  • Household Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Nitrate
  • Nitrite
  • Non-Metal
  • Pesticide
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more
Number of Targets: 16
T3D0217Potassium-40
13966-00-2
K
39.964 g/mol
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  • Food Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The ionizing radiation produced by potassium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more
Number of Targets: 1
T3D0219Antimony
7440-36-0
Sb
121.760 g/mol
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  • Antimony Compound
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Metal
  • Metalloid
  • Natural Compound
  • Pollutant
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more
Number of Targets: 20
T3D0221Thorium-227
15623-47-9
Th
227.028 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
  • Thorium Compound
The ionizing radiation produced by thorium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal cha...more
Number of Targets: 1
T3D02222,4,5-Trichlorophenol
95-95-4
C6H3Cl3O
197.446 g/mol
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  • Aromatic Hydrocarbon
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pollutant
  • Synthetic Compound
2,4,5-Trichlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more
Number of Targets: 6
T3D0223Arsenate
15584-04-00
AsH3O4
141.943 g/mol
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  • Arsenic Compound
  • Food Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Pesticide
  • Pollutant
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase. By compe...more
Number of Targets: 44
T3D0224Arsenic trioxide
1327-53-3
As2O3
197.841 g/mol
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  • Antineoplastic Agent
  • Arsenic Compound
  • Drug
  • Homeopathic Agent
  • Inorganic Compound
  • Metabolite
  • Metalloid
  • Pesticide
  • Pollutant
  • Synthetic Compound
The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptos...more
Number of Targets: 51
T3D0225Phorate
298-02-2
C7H17O2PS3
260.377 g/mol
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  • Ester
  • Ether
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Phorate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more
Number of Targets: 5
T3D0226Benzo[e]pyrene
192-97-2
C20H12
252.309 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 3
T3D0229Dimethoate
60-51-5
C5H12NO3PS2
229.257 g/mol
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  • Amide
  • Amine
  • Ester
  • Household Toxin
  • Insecticide
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Dimethoate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more
Number of Targets: 10
T3D0230Actinium-227
14952-40-0
Ac
227.028 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metal
  • Natural Compound
  • Pollutant
  • Radioactive
  • Radioactive Isotope
The ionizing radiation produced by actinium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal ch...more
Number of Targets: 1
T3D02324-Aminobiphenyl
92-67-1
C12H11N
169.222 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Cigarette Toxin
  • Food Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Metabolite
  • Organic Compound
  • Pollutant
  • Synthetic Compound
4-Aminobiphenyl requires metabolic activation in order to exert its toxicity. This is catalyzed by N-hydroxylation via cytochrome P450 1A2, then followed by O-sulfatio...more
Number of Targets: 2
T3D0233Pyrethrum
8003-34-7
C22H28O5
372.455 g/mol
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  • Ester
  • Ether
  • Household Toxin
  • Organic Compound
  • Pesticide
  • Pyrethrin
  • Pyrethroid
  • Synthetic Compound
Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more
Number of Targets: 20
T3D0234Arsine
7784-42-1
AsH3
77.945 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Synthetic Compound
Arsine enters the bloodstream and crosses the alveolo-capillary membrane into red blood cells. Here it preferentially binds to hemoglobin and is oxidized to an arsenic...more
Number of Targets: 10
T3D0235(±)-Naled
300-76-5
C4H7Br2Cl2O4P
380.784 g/mol
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  • Bromide Compound
  • Ester
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organobromide
  • Organochloride
  • Organophosphate
  • Pesticide
  • Synthetic Compound
(±)-Naled is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more
Number of Targets: 11
T3D0237Ethoprop
13194-48-4
C8H19O2PS2
242.339 g/mol
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  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Ethoprop is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 8
T3D0240Dichlorvos
62-73-7
C4H7Cl2O4P
220.976 g/mol
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  • Ester
  • Food Toxin
  • Household Toxin
  • Insecticide
  • Metabolite
  • Organic Compound
  • Organochloride
  • Organophosphate
  • Pesticide
  • Pollutant
  • Synthetic Compound
Dichlorvos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more
Number of Targets: 7
T3D0241Calcium arsenate
7778-44-1
As2Ca3O8
398.072 g/mol
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  • Arsenic Compound
  • Inorganic Compound
  • Pesticide
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0242Mercuric chloride
7487-94-7
Cl2Hg
271.500 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Mercury Compound
  • Pollutant
  • Synthetic Compound
High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more
Number of Targets: 87
T3D0243Sodium arsenite
7784-46-5
AsNaO2
129.910 g/mol
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  • Arsenic Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metalloid
  • Pollutant
  • Synthetic Compound
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more
Number of Targets: 44
T3D0244Formaldehyde
50-00-0
CH2O
30.026 g/mol
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  • Aldehyde
  • Cigarette Toxin
  • Cosmetic Toxin
  • Disinfectant
  • Fixative
  • Food Toxin
  • Household Toxin
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Pollutant
It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde dehydrogenase activity, allowing the unmetabolized intact molecule to ex...more
Number of Targets: 3
T3D02452-Chlorophenol
95-57-8
C6H5ClO
128.556 g/mol
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  • Aromatic Hydrocarbon
  • Disinfectant
  • Household Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
2-chlorophenol works as a weak uncoupler of oxidative phosphorylation and inhibitors of cellular respiration. The ability of chlorophenols to uncouple oxidative phosph...more
Number of Targets: 5
T3D0246Phenanthrene
85-01-8
C14H10
178.229 g/mol
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  • Aromatic Hydrocarbon
  • Food Toxin
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Pollutant
  • Polycyclic Aromatic Hydrocarbon
The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more
Number of Targets: 6
T3D0247Hydrogen fluoride
7664-39-3
FH
20.006 g/mol
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  • Fluoride Compound
  • Household Toxin
  • Industrial By-product/Pollutant
  • Industrial Precursor/Intermediate
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Non-Metal
  • Pollutant
  • Synthetic Compound
In addition to being a highly corrosive liquid, hydrofluoric acid is also a contact poison. As with most acids HF can cause tissue burns through the denaturation of pr...more
Number of Targets: 7
Displaying toxins 176 - 200 of 3678 in total