Browsing Toxin Types
Adjuvant, Immunologic (2)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2972 | Melatonin | 73-31-4 | Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts ...more |
| T3D4241 | Dehydroepiandrosterone | 53-43-0 | Although it predominantly functions as an endogenous precursor to more potent androgens such as t...more |
Adrenergic Agent (8)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2706 | Amphetamine | 300-62-9 | Amphetamines stimulate the release of norepinephrine from central adrenergic receptors. At higher...more |
| T3D2709 | Phentermine | 122-09-8 | Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a par...more |
| T3D2786 | Methylphenidate | 113-45-1 | Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transpo...more |
| T3D2919 | Benzphetamine | 156-08-1 | Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of...more |
| T3D3040 | Ephedrine | 299-42-3 | Ephedrine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more |
| T3D3051 | Dextroamphetamine | 51-64-9 | The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinep...more |
| T3D3052 | Methamphetamine | 537-46-2 | Methamphetamine enters the brain and triggers a cascading release of norepinephrine, dopamine and...more |
| T3D3480 | Atenolol | 29122-68-7 | Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines ...more |
Adrenergic alpha-1 Receptor Antagonist (2)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3517 | Labetalol | 36894-69-6 | Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastere...more |
| T3D3537 | Terazosin | 70024-40-7 | Terazosin selectively and competitively inhibits vascular postsynaptic alpha(1)-adrenergic recept...more |
Adrenergic alpha-2 Receptor Agonist (5)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2829 | Clonidine | 4205-90-7 | Clonidine acts as an agonist at presynaptic alpha(2)-receptors in the nucleus tractus solitarius ...more |
| T3D2862 | Tizanidine | 51322-75-9 | Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agoni...more |
| T3D3478 | Methyldopa | 555-29-3 | Although the mechanism of action has yet to be conclusively demonstrated, the antihypertensive ef...more |
| T3D3487 | Brimonidine | 59803-98-4 | Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hyp...more |
| T3D3577 | Methyldopa | 555-30-6 | Although the mechanism of action has yet to be conclusively demonstrated, the resultant hypotensi...more |
Adrenergic alpha-Agonist (6)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2460 | Ergotamine | 113-15-5 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D2829 | Clonidine | 4205-90-7 | Clonidine acts as an agonist at presynaptic alpha(2)-receptors in the nucleus tractus solitarius ...more |
| T3D2862 | Tizanidine | 51322-75-9 | Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agoni...more |
| T3D3478 | Methyldopa | 555-29-3 | Although the mechanism of action has yet to be conclusively demonstrated, the antihypertensive ef...more |
| T3D3487 | Brimonidine | 59803-98-4 | Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hyp...more |
| T3D4154 | Norepinephrine | 51-41-2 | Uremic toxins such as noradrenalin are actively transported into the kidneys via organic ion tran...more |
Adrenergic alpha-Antagonist (3)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2767 | Mirtazapine | 61337-67-5 | Mirtazapine acts as an antagonist at central pre-synaptic alpha(2)-receptors, inhibiting negative...more |
| T3D3517 | Labetalol | 36894-69-6 | Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastere...more |
| T3D3537 | Terazosin | 70024-40-7 | Terazosin selectively and competitively inhibits vascular postsynaptic alpha(1)-adrenergic recept...more |
Adrenergic Antagonist (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2713 | Reserpine | 50-55-5 | Reserpine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the se...more |
Adrenergic beta-1 Receptor Antagonist (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3480 | Atenolol | 29122-68-7 | Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines ...more |
Adrenergic beta-2 Receptor Agonist (2)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D4734 | Salmeterol | 89365-50-4 | Salmeterol's long, lipophilic side chain binds to exosites near beta(2)-receptors in the lungs an...more |
| T3D4735 | Salbutamol | 18559-94-9 | Salbutamol is a beta(2)-adrenergic agonist and thus it stimulates beta(2)-adrenergic receptors. B...more |