| T3D0026 | Benzidine | 92-87-5 | N-acetylated benzidine metabolites are believed to form adducts with nucleic acids. Carcinogenesi...more |
| T3D0040 | 3,3'-Dichlorobenzidine | 91-94-1 | 3,3’-Dichlorobenzidine's mechanism of toxicity derives mainly from the adduction of DNA by its me...more |
| T3D0092 | Cyclotrimethylenetrinitramine | 121-82-4 | RDX can get into the lungs after breathing in the fumes of burning RDX or breathing in the dust f...more |
| T3D0112 | n-Nitrosodi-n-propylamine | 621-64-7 | Reactive metabolites of n-nitrosodi-n-propylamine are believed to form adducts with DNA, resultin...more |
| T3D0131 | Amosite asbestos | 12172-73-5 | When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory...more |
| T3D0152 | 4,4'-Methylenebis(2-chloroaniline) | 101-14-4 | MBOCA's carcinogenicity is thought to be a result of its ability to bind to DNA, hemoglobin, and ...more |
| T3D0167 | 1,2-Diphenylhydrazine | 122-66-7 | Two of the known metabolites, aniline and benzidine, may contribute to the toxicity and/or carcin...more |
| T3D0199 | N-Nitrosodimethylamine | 62-75-9 | The mechanism of NDMAinduced liver toxicity is not clearly understood but may be related to alkyl...more |
| T3D0229 | Dimethoate | 60-51-5 | Dimethoate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibit...more |
| T3D0232 | 4-Aminobiphenyl | 92-67-1 | 4-Aminobiphenyl requires metabolic activation in order to exert its toxicity. This is catalyzed b...more |
| T3D0252 | N,N-Dimethylformamide | 1968-12-02 | While the mechanism of action of dimethyl formamide has not bee fully elucidated, thiocarbamate p...more |
| T3D0275 | Adamsite | 578-94-9 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0300 | Arsanilic acid | 98-50-0 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0312 | 4,4-Arsenobis(2-aminophenol) dihydrochloride | 139-93-5 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0313 | [4-(Aminocarbonyl-amino)phenyl] arsonic acid | 121-59-5 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0314 | Tryparsamide | 554-72-3 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0316 | Sodium arsanilate | 127-85-5 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D0381 | Cadmium phosphate | 13477-17-3 | Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are ob...more |
| T3D0674 | Dicobalt edetate | 36499-65-7 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D0677 | Hydroxocobalamin | 13422-51-0 | Vitamin B12 exists in four major forms referred to collectively as cobalamins; deoxyadenosylcobal...more |
| T3D0678 | Lithium cobalt oxide | 12190-79-3 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D0680 | Salcomine | 14167-18-1 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D0682 | Tris(ethylenediamine)cobalt(III) chloride | 207802-43-5 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D0782 | 1,3-Dinitrobenzene | 99-65-0 | In the red blood cell, 1,3-DNB induces formation of methemoglobin, leading to cyanosis. Reduction...more |
| T3D0797 | Imidacloprid | 105827-78-9 | Imidacloprid acts on the nicotinic acetylcholine receptor; the chlorination inhibits degradation ...more |
| T3D0798 | Fipronil | 120068-37-3 | Fipronil blocks the passage of chloride ions through the GABA-regulated chloride channel, disrupt...more |
| T3D0799 | Nicotine | 54-11-5 | Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These ...more |
| T3D0807 | Dicamba | 1918-00-9 | Not Available |
| T3D0810 | Alachlor | 15972-60-8 | Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) ...more |
| T3D0811 | Acetochlor | 34256-82-1 | Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) ...more |
| T3D0812 | Glufosinate | 51276-47-2 | Glufosinate irreversibly inhibits the enzyme glutamine synthetase, which decreases ammonia detoxi...more |
| T3D0871 | Antimony pentasulfide | 1315-04-4 | The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible ...more |
| T3D0890 | Pendimethalin | 40487-42-1 | Inhibits cell division and cell elongation (L800). |
| T3D0893 | 2,3,5-Trimethylphenyl methylcarbamate | 2655-15-4 | 2,3,5-Trimethylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibito...more |
| T3D0896 | 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate | 14357-82-5 | 2-Chloro-4,5-xylyl N-hydroxy-N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE)...more |
| T3D0897 | 2-Cyclopentylphenyl methylcarbamate | 3282-00-6 | 2-Cyclopentylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor....more |
| T3D0898 | 2-Hydroxyphenyl methylcarbamate | 10309-97-4 | 2-Hydroxyphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Car...more |
| T3D0901 | 3,5-Diisopropylphenyl methylcarbamate | 330-64-3 | 3,5-Diisopropylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibito...more |
| T3D0902 | 3,5-Dimethylphenyl methylcarbamate | 2655-14-3 | 3,5-Dimethylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. ...more |
| T3D0903 | 3-Hydroxy-carbofuran | 16655-82-6 | 3-Hydroxy-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates for...more |
| T3D0904 | 3-Iodo-2-propynyl butyl carbamate | 55406-53-6 | 3-Iodo-2-propynyl butyl carbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. C...more |
| T3D0905 | 3-Oxo-carbofuran | 16709-30-1 | 3-Oxo-carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form un...more |
| T3D0906 | 3-tert-Butylphenyl sec-butylcarbamate | 97508-29-7 | 3-tert-Butylphenyl sec-butylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibito...more |
| T3D0907 | 4-(Methylamino)-3,5-xylyl methylcarbamate | 10389-50-1 | 4-(Methylamino)-3,5-xylyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhi...more |
| T3D0908 | 4-(Methylthio)-m-tolyl methylcarbamate | 3566-00-5 | 4-(Methylthio)-m-tolyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibit...more |
| T3D0909 | 4-Amino-3,5-xylyl methylcarbamate | 831-76-5 | 4-Amino-3,5-xylyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. C...more |
| T3D0910 | 4-Chlorophenyl-N-methylcarbamate | 2620-53-3 | 4-Chlorophenyl-N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Ca...more |
| T3D0911 | 4-Ethylthiophenyl methylcarbamate | 18809-57-9 | 4-Ethylthiophenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. C...more |
| T3D0912 | 4-Methylformamido-3,5-xylyl methylcarbamate | 10233-94-0 | 4-Methylformamido-3,5-xylyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) in...more |
| T3D0913 | 5,6,7,8-Tetrahydro-1-naphthyl methylcarbamate | 1136-84-1 | 5,6,7,8-Tetrahydro-1-naphthyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) ...more |
| T3D0915 | 6-Methyl-2-propyl-4-pyrimidinyl dimethylcarbamate | 2532-49-2 | 6-Methyl-2-propyl-4-pyrimidinyl dimethylcarbamate is a cholinesterase or acetylcholinesterase (AC...more |
| T3D0916 | Alanycarb | 83130-01-2 | Alanycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D0918 | Aldicarb sulfoxide | 1646-87-3 | Aldicarb sulfoxide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form ...more |
| T3D0919 | Aldicarb | 116-06-3 | Aldicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0920 | Aldoxycarb | 1646-88-4 | Aldoxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0923 | Asulam | 3337-71-1 | Asulam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (...more |
| T3D0924 | Asulam, sodium salt | 2302-17-2 | Asulam, sodium salt is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesteras...more |
| T3D0925 | Barban | 101-27-9 | Barban is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable com...more |
| T3D0926 | Bendiocarb | 22781-23-3 | Bendiocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0928 | Benomyl | 17804-35-2 | Benomyl targets beta tubulin in actively dividing cells. It binds to microtubules, interfering wi...more |
| T3D0929 | Benthiavalicarb | 413615-35-7 | Benthiavalicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form uns...more |
| T3D0930 | Benthiavalicarb-isopropyl | 177406-68-7 | Benthiavalicarb-isopropyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamate...more |
| T3D0934 | 3-(1-Methylbutyl)phenyl N-methylcarbamate | 2282-34-0 | 3-(1-Methylbutyl)phenyl N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhi...more |
| T3D0935 | 3-(1-Ethylpropyl)phenyl methylcarbamate | 672-04-8 | 3-(1-Ethylpropyl)phenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibi...more |
| T3D0936 | Butacarb | 2655-19-8 | Butacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0938 | Butoxycarboxim | 34681-23-7 | Butoxycarboxim is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unst...more |
| T3D0939 | Carbanolate | 671-04-5 | Carbanolate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0940 | Carbaril | 63-25-2 | Carbaril is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0941 | Carbasulam | 1773-37-1 | Carbasulam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0943 | Carbetamide | 16118-49-3 | Carbetamide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0944 | Carbofuran | 1563-66-2 | Carbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0946 | Carboxazole | 55808-13-4 | Carboxazole is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0947 | Chlorbufam | 1967-16-4 | Chlorbufam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibit...more |
| T3D0948 | Chlorprocarb | 23121-99-5 | Chlorprocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0949 | Chlorpropham | 101-21-3 | Chlorpropham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0950 | Cloethocarb | 51487-69-5 | Cloethocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0951 | Cycloate | 1134-23-2 | Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity...more |
| T3D0952 | Cypendazole | 28559-00-4 | Cypendazole is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0953 | Debacarb | 62732-91-6 | Debacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0954 | Decarbofuran | 1563-67-3 | Decarbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0955 | Desmedipham | 13684-56-5 | Desmedipham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0957 | Dichlormate | 1966-58-1 | Dichlormate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0959 | Diethofencarb | 87130-20-9 | Diethofencarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unsta...more |
| T3D0960 | Dimetan | 122-15-6 | Dimetan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable co...more |
| T3D0961 | Dimetilan | 644-64-4 | Dimetilan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D0962 | Dioxacarb | 6988-21-2 | Dioxacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D0964 | Ethiofencarb | 29973-13-5 | Ethiofencarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0966 | Fenasulam | 78357-48-9 | Fenasulam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D0967 | Fenethacarb | 30087-47-9 | Fenethacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0968 | Fenobucarb | 3766-81-2 | Fenobucarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0969 | Fenoxycarb | 72490-01-8 | Fenoxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0970 | Formetanate | 22259-30-9 | Formetanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0971 | Formetanate hydrochloride | 23422-53-9 | Formetanate hydrochloride is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamate...more |
| T3D0972 | Formparanate | 17702-57-7 | Formparanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0973 | Fosamine | 59682-52-9 | Fosamine is an eye irritant. It likely binds to or modifies the TRPA1 protein which leads to a l...more |
| T3D0975 | Hyquincarb | 56716-21-3 | Hyquincarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0976 | Isolan | 119-38-0 | Isolan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable com...more |
| T3D0977 | 2-Isopropylphenyl methylcarbamate | 2631-40-5 | 2-Isopropylphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. C...more |
| T3D0978 | Karbutilate | 4849-32-5 | Karbutilate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0979 | m-Cumenyl methylcarbamate | 64-00-6 | m-Cumenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamate...more |
| T3D0981 | Methiocarb | 2032-65-7 | Methiocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D0982 | Methiocarb sulfone | 2179-25-1 | Methiocarb sulfone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form ...more |
| T3D0983 | Methiocarb sulfoxide | 2635-10-1 | Methiocarb sulfoxide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates for...more |
| T3D0984 | Methomyl | 16752-77-5 | Methomyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0987 | Mobam | 1079-33-0 | Mobam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable comp...more |
| T3D0988 | Molinate | 2212-67-1 | Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity...more |
| T3D0989 | Nitrilacarb | 29672-19-3 | Nitrilacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D0990 | o-(2-Propynyloxy)phenyl methylcarbamate | 3279-46-7 | o-(2-Propynyloxy)phenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibi...more |
| T3D0991 | Oms 22 | 3566-09-4 | Oms 22 is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable com...more |
| T3D0992 | Oxamyl | 23135-22-0 | Oxamyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable com...more |
| T3D0994 | Phenmedipham | 13684-63-4 | Phenmedipham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D0996 | Potassium asulam | 14089-43-1 | Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity...more |
| T3D0998 | Promacyl | 34264-24-9 | Promacyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D0999 | Promecarb | 2631-37-0 | Promecarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D1000 | Propamocarb hydrochloride | 25606-41-1 | Propamocarb hydrochloride is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamate...more |
| T3D1001 | Propamocarb | 24579-73-5 | Propamocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D1002 | Propham | 122-42-9 | Propham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable co...more |
| T3D1003 | Propoxur | 114-26-1 | Propoxur is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable c...more |
| T3D1004 | Proximphan | 2828-42-4 | Proximphan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable...more |
| T3D1005 | Pyrolan | 87-47-8 | Pyrolan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable co...more |
| T3D1006 | Sulfallate | 95-06-7 | The metabolic products of triallate, diallate and sulfallate appear to be mutagenic or carcinogen...more |
| T3D1007 | Sulfocarbathione | 114654-31-8 | Sulfocarbathione is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form un...more |
| T3D1008 | Swep | 1918-18-9 | Swep is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable compl...more |
| T3D1009 | Tazimcarb | 40085-57-2 | Tazimcarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D1010 | Terbucarb | 1918-11-2 | Terbucarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D1011 | Thiobencarb | 28249-77-6 | Thiobencarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstabl...more |
| T3D1012 | Thiocarboxime | 25171-63-5 | Thiocarboxime is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unsta...more |
| T3D1014 | Thiofanox | 39196-18-4 | Thiofanox is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D1015 | Tillam sulfoxide | 51892-60-5 | Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity...more |
| T3D1016 | Tiocarbazil | 36756-79-3 | Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity...more |
| T3D1018 | Trimethacarb | 2686-99-9 | Trimethacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstab...more |
| T3D1021 | Xylylcarb | 2425-10-7 | Xylylcarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable ...more |
| T3D1028 | Tetramethrin | 7696-12-0 | Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium...more |
| T3D1039 | Fluvalinate | 69409-94-5 | Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium...more |
| T3D1043 | Emamectin B1a | 121124-29-6 | It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chlo...more |
| T3D1044 | Emamectin B1b | 121424-52-0 | It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chlo...more |
| T3D1045 | 2-[(2E)-2-(Nitromethylidene)pyrrolidin-1-yl]acetonitrile | 1164504-23-7 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually bloc...more |
| T3D1046 | 2-(Nitromethylene)imidazolidine | 13623-98-8 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1047 | (2Z)-1-Methyl-2-(nitromethylidene)pyrrolidine | 26171-05-1 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1048 | 2-Nitromethylene-azepane | 61018-99-3 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1049 | 2-Nitromethylene-piperidine | 50902-03-9 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1051 | (2E)-3-Benzyl-2-(nitromethylidene)-1,3-thiazolidine | 94776-91-7 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1053 | Thiazolidine, 2-(nitromethylene) | 94662-61-0 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1054 | (4E)-4-(Nitromethylidene)-1,2,3,5-tetrahydro-3-benzazepine | 58350-08-6 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1055 | (2E)-2-(Nitromethylidene)-1,3-thiazinane | 58842-20-9 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1056 | 2-(Nitromethylidene)-1,3-thiazolidine | 94662-60-9 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1057 | (2Z)-2-(Nitromethylidene)-1,3-thiazolidine | Not Available | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1058 | (2Z)-1-Ethyl-2-(nitromethylidene)pyrrolidine | 26171-04-0 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1059 | (2E)-2-(Nitromethylidene)-1-prop-2-enylpyrrolidine | 40990-27-0 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1060 | (2Z)-1-Benzyl-2-(nitromethylidene)pyrrolidine | 57734-58-4 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1062 | (2E)-1-Methyl-2-(nitromethylidene)pyrrolidine | 94662-64-3 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1063 | 2-[2-(Nitromethylidene)pyrrolidin-1-yl]acetonitrile | Not Available | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1064 | [2-(Nitromethylene)-1-pyrrolidinyl]acetonitrile | 91417-82-2 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1065 | 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-2,3,4,5-tetrahydro-1-benzazepine | 24483-78-1 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1066 | (3Z)-2-Ethyl-3-(nitromethylidene)-3a,4,5,6,7,7a-hexahydro-1H-isoindole | 56593-86-3 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1069 | 1-(Cyclopropylmethyl)-2-(nitromethylidene)pyrrolidine | 60737-54-4 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1076 | Methyl (5Z)-3-amino-5-(nitromethylidene)dithiole-4-carboxylate | 78649-93-1 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1084 | 1-[(6-Chloropyridin-3-yl)methyl]-2-(nitromethylidene)-1,3-diazinane | 72126-78-4 | Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blo...more |
| T3D1086 | Amidochlor | 40164-67-8 | Binds to nAChRs in nervous systems. It also causes endocrine disruption in humans by binding to a...more |
| T3D1087 | Butachlor | 23184-66-9 | Binds to nAChRs in nervous systems. Also causes endocrine disruption in humans by binding to and ...more |
| T3D1088 | (±)-Metalaxyl | 57837-19-1 | Binds to nAChRs in nervous systems. It also causes endocrine disruption in humans by binding to a...more |
| T3D1089 | Metolachlor | 51218-45-2 | Metolachlor acts by inhibition of elongases and of the geranylgeranyl pyrophosphate (GGPP) cyclas...more |
| T3D1090 | Propachlor | 1918-16-7 | Propachlor poisoning causes an induction of microsomal hepatic UDPGT activity, which produces inc...more |
| T3D1104 | Barium ferrate | 13773-23-4 | Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellu...more |
| T3D1137 | Mangafodipir | 140678-14-4 | Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and recept...more |
| T3D1138 | Methylcyclopentadienyl manganese tricarbonyl | 12108-13-3 | Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and recept...more |
| T3D1220 | Tetramminecopper(II) sulfate | 10380-29-7 | Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothion...more |
| T3D1221 | Copper(II) hydroxide sulfate | 1332-03-2 | Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothion...more |
| T3D1231 | Cupriethylenediamine | 13426-91-0 | Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothion...more |
| T3D1293 | Acetarsol | 97-44-9 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D1295 | Arsenamide | 531-72-6 | Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more |
| T3D1350 | Methylmercuric dicyanamide | 502-39-6 | High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is b...more |
| T3D1357 | Mercaptomerin | 20223-84-1 | High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is b...more |
| T3D1360 | Meralluride | 140-20-5 | High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is b...more |
| T3D1362 | Mersalyl acid | 486-67-9 | High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is b...more |
| T3D1393 | cis-Dichlorobis(ethylenediamine)cobalt(III) chloride | 14040-32-5 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D1394 | trans-Dichlorobis(ethylenediamine)cobalt(III) chloride | 14040-33-6 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D1404 | Bis(3-fluorosalicylaldehyde)-ethylenediimine-cobalt | 62207-76-5 | Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based process...more |
| T3D1416 | Nickel bis(dibutyldithiocarbamate) | 13927-77-0 | Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin...more |
| T3D1452 | Ammonium tetrathiocyanato-diamminechromate(III) | 13573-16-5 | Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-pro...more |
| T3D1460 | Zinc diethyldithiocarbamate | 14324-55-1 | Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, mos...more |
| T3D1461 | Zinc laurate | 2452-01-9 | Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, mos...more |
| T3D1465 | Zinc dimethyldithiocarbamate | 137-30-4 | Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, mos...more |
| T3D1466 | Zineb | 12122-67-7 | Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, mos...more |
| T3D1501 | Dihydroxyaluminium | 13682-92-3 | The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more |
| T3D1585 | cis-Diamminedichloro-palladium(II) | 14323-43-4 | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more |
| T3D1586 | trans-Diamminedichloro-palladium(II) | 13782-33-7 | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more |
| T3D1588 | trans-Diamminedinitro-palladium(II) | 28068-05-5 | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more |
| T3D1595 | Tetraammine palladium(II) chloride | 13815-17-3 | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more |
| T3D1596 | Tetraammine palladium hydrogen carbonate | 134620-00-1 | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more |
| T3D1679 | Cyanoacetamide | 107-91-5 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D1690 | Beta-Aminopropionitrile | 151-18-8 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D1771 | Zirconium(IV) bromide | 1377-25-8 | Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water ...more |
| T3D1782 | Bromodeoxyuridine | 59-14-3 | 5-bromodeoxyuridine acts on DNA. It induces a random DNA point mutation via base substitution. Th...more |
| T3D1798 | Dibrompropamidine | 496-00-4 | Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water ...more |
| T3D1841 | Selenium dimethyldithiocarbamate | 144-34-3 | Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especi...more |
| T3D1849 | Tau-fluvalinate | 102851-06-9 | Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a ne...more |
| T3D1900 | Tris(4-bromophenyl)aminium hexachloroantimonate | 24964-91-8 | The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible...more |
| T3D1902 | Tris(dimethylamino)antimony | 7289-92-1 | The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible...more |
| T3D2339 | Cercosporamide | 131436-22-1 | Dibenzofurans bind the aryl hydrocarbon receptor, which increases its ability to activate transcr...more |
| T3D2378 | Taziprinone | 79253-92-2 | Dibenzofurans bind the aryl hydrocarbon receptor, which increases its ability to activate transcr...more |
| T3D2450 | alpha-Amanitin | 23109-05-9 | Amanitin has an unusually strong and specific attraction to the enzyme RNA polymerase II. Upon in...more |
| T3D2454 | L-Coprine | 58919-61-2 | It metabolises to 1-aminocyclopropanol, a closely-related chemical to Disulfiram and exhibits the...more |
| T3D2455 | Ibotenic acid | 2552-55-8 | A portion of ibotenic acid is metabolized to muscimol, a potent GABAA agonist, activating the rec...more |
| T3D2456 | Muscimol | 18174-72-6 | Muscimol is a potent GABAA agonist, activating the receptor for the brain's major inhibitory neur...more |
| T3D2457 | Psilocybin | 520-52-5 | Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agoni...more |
| T3D2458 | Psilocin | 520-53-6 | Psilocin acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics ...more |
| T3D2460 | Ergotamine | 113-15-5 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D2462 | Palytoxin | 77734-91-9 | Palytoxin targets the sodium-potassium pump protein by binding to the molecule such that the mole...more |
| T3D2467 | Phalloidin | 17466-45-4 | It binds actin, preventing its depolymerization and poisoning the cell. Phalloidin binds specific...more |
| T3D2468 | Prophalloin | 67739-84-8 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2469 | Phalloin | 28227-92-1 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2470 | Phallisin | 19774-69-7 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2471 | Phallacidin | 26645-35-2 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2472 | Phallacin | 53568-40-4 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2473 | Phallisacin | 58286-46-7 | Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specif...more |
| T3D2474 | Naftidrofuryl | 31329-57-4 | Naftidrofuryl blocks the type 2 serotonin (5-HT2) receptors and thereby inhibits the effects of s...more |
| T3D2477 | Insulin | 11061-68-0 | Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty ac...more |
| T3D2478 | Levofloxacin | 100986-85-4 | Levofloxacin inhibits bacterial type II topoisomerases, topoisomerase IV and DNA gyrase. Levoflox...more |
| T3D2479 | Vindesine | 53643-48-4 | Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin...more |
| T3D2480 | Amitriptyline | 50-48-6 | Amitriptyline is metabolized to nortriptyline which inhibits the reuptake of norepinephrine and s...more |
| T3D2481 | Ricin | 9009-86-3 | Pure ricin consists of a neutral A chain and an acidic B chain connected by S--S bonds. The A cha...more |
| T3D2482 | Dapsone | 80-08-0 | Dapsone acts against bacteria and protozoa in the same way as sulphonamides, that is by inhibitin...more |
| T3D2483 | Glipizide | 29094-61-9 | Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell sur...more |
| T3D2484 | Tetrodotoxin | 4368-28-9 | Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is...more |
| T3D2486 | Methotrexate | 59-05-2 | Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading t...more |
| T3D2487 | Apamin (Apis mellifera) | 24345-16-2 | Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and s...more |
| T3D2489 | Philanthotoxin | 77108-00-0 | Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kai...more |
| T3D2490 | alpha-Pompilidotoxin | 202075-91-0 | Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating s...more |
| T3D2491 | beta-Pompilidotoxin | 216064-36-7 | Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating s...more |
| T3D2492 | Holocyclotoxin | 88254-04-0 | Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) |
| T3D2493 | Poneratoxin | 137084-94-7 | Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synapti...more |
| T3D2494 | omega-Agatoxin | 145017-83-0 | omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junc...more |
| T3D2495 | Atracotoxin, omega- (Hadronyche versuta) | 193981-10-1 | omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812) |
| T3D2496 | Versutoxin | 114264-83-4 | Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 i...more |
| T3D2497 | Robustoxin | 91728-12-0 | Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 i...more |
| T3D2498 | Grammotoxin | 152617-90-8 | Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the ...more |
| T3D2499 | Huwentoxin | 526224-73-7 | Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, ...more |
| T3D2500 | alpha-Latrotoxin | 65988-34-3 | alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons...more |
| T3D2501 | Phrixotoxin | 880886-00-0 or 221872-97-5 | Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels....more |
| T3D2502 | Stromatoxin | 1262235-00-6 | Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the ...more |
| T3D2503 | Phoneutriatoxin | Not Available | Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) |
| T3D2505 | Heteropodatoxin | 189120-72-7 | Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating m...more |
| T3D2506 | Agitoxin | 155646-21-2 | Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammali...more |
| T3D2507 | Charybdotoxin | 95751-30-7 | Charybdotoxin is a neurotoxin that blocks calcium-activated and voltage gated potassium channels ...more |
| T3D2508 | Chlorotoxin | 163515-35-3 | Chlorotoxin blocks small conductance chloride channels. (L1043) |
| T3D2509 | Cobatoxin | 211688-17-4 | Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) |
| T3D2510 | alpha-Cobratoxin | 769933-79-1 | alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes ...more |
| T3D2511 | kappa-Hefutoxin | 478621-50-0 | kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kine...more |
| T3D2512 | Iberiotoxin | 129203-60-7 | Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channel...more |
| T3D2513 | Imperatoxin-A | 172451-37-5 | Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum...more |
| T3D2514 | Imperatoxin-1 | Not Available | Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulu...more |
| T3D2515 | Kaliotoxin | 145199-73-1 | Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. ...more |
| T3D2516 | Kaliotoxin-1 | 150769-72-5 | Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. ...more |
| T3D2517 | Kaliotoxin-2 | 159605-22-8 | Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. ...more |
| T3D2518 | Kaliotoxin-3 | 223246-26-2 | Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. ...more |
| T3D2519 | Kurtoxin | 820959-57-7 | Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium cha...more |
| T3D2520 | Margatoxin | 145808-47-5 | Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurot...more |
| T3D2521 | Maurotoxin | 188240-41-7 | Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059) |
| T3D2522 | Noxiustoxin | 85205-49-8 | Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating po...more |
| T3D2523 | Scyllatoxin | 142948-19-4 | Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow...more |
| T3D2524 | Slotoxin | 144026-79-9 | Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of ...more |
| T3D2525 | Tamapin | 508220-81-3 | Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent pot...more |
| T3D2526 | Tityustoxin (Tityus serrulatus ) | 39465-37-7 | Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhi...more |
| T3D2527 | Batrachotoxin | 23509-16-2 | Batrachotoxins act on sodium channels by modifying both their ion selectivity and voltage sensiti...more |
| T3D2528 | Histrionicotoxin | 34272-51-0 | Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1...more |
| T3D2529 | Pumiliotoxin | 73376-35-9 | Pumiliotoxin affects voltage-gated calcium channels, interfering with muscle contraction in the h...more |
| T3D2530 | Epibatidine | 140111-52-0 | Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074) |
| T3D2531 | Allopumiliotoxin | 73376-38-2 | Allopumiliotoxins may affect sodium and potassium channels in cells and inhibit calcium-dependent...more |
| T3D2534 | Bufotenin | 487-93-4 | Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partia...more |
| T3D2537 | alpha-Bungarotoxin | 11032-79-4 | alpha-Bungarotoxin binds irreversibly and competitively to muscular and neuronal nicotinic acetyl...more |
| T3D2538 | beta-Bungarotoxin | 12778-32-4 | beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and ...more |
| T3D2539 | Calciseptine | 134710-25-1 | Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth m...more |
| T3D2540 | Calcicludine | 178037-96-2 | Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092) |
| T3D2541 | Cardiotoxin (Naja atra) | 155808-00-7 | Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activi...more |
| T3D2542 | Crotamine | 58740-15-1 | Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity...more |
| T3D2543 | Crotoxin | 9007-40-3 | Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release fr...more |
| T3D2544 | Convulxin | 37206-04-5 | Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platel...more |
| T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) | 119128-61-9 | Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby pr...more |
| T3D2546 | Dendrotoxin (Dendroaspis angusticeps) | 74504-53-3 | Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby pr...more |
| T3D2547 | Taicatoxin | 112154-17-3 | Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small c...more |
| T3D2549 | Eledoisin (Eledone cirrhosa) | 69-25-0 | Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are p...more |
| T3D2551 | Saxitoxin | 35523-89-8 | Saxitoxin blocks voltage-gated sodium channels of nerve cells. (L1115) |
| T3D2552 | Sticholysin | 269658-04-0; 183449-91-4 | Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely pr...more |
| T3D2553 | 4-Aminopyridine | 504-24-5 | 4-Aminopyridine blocks potassium channels and thereby increases acetylcholine, and possibly norad...more |
| T3D2554 | Baclofen | 1134-47-0 | Baclofen is a direct agonist at GABAB receptors. The precise mechanism of action of Baclofen is n...more |
| T3D2555 | Quetiapine | 111974-69-7 | The mechanism of action of quetiapine, as with other drugs used to treat schizophrenia, is unknow...more |
| T3D2556 | Flecainide | 54143-55-4 | Flecainide acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure ...more |
| T3D2557 | Disulfiram | 97-77-8 | Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism fo...more |
| T3D2560 | Amantadine | 768-94-5 | The mechanism of its antiparkinsonic effect is not fully understood, but it appears to be releasi...more |
| T3D2561 | Chloroquine | 54-05-7 | The mechanism of plasmodicidal action of chloroquine is not completely certain. Like other quinol...more |
| T3D2565 | Promazine | 58-40-2 | Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C...more |
| T3D2568 | Ceftriaxone | 73384-59-5 | Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-la...more |
| T3D2569 | Enoxaparin | Not Available | The mechanism of action of enoxaparin is antithrombin-dependent. It acts mainly by accelerating t...more |
| T3D2570 | Lamotrigine | 84057-84-1 | One proposed mechanism of action of Lamotrigine, the relevance of which remains to be established...more |
| T3D2571 | Acetaminophen | 103-90-2 | Paracetamol toxicity is one of the most common causes of poisoning worldwide. The toxic effects o...more |
| T3D2573 | Acrylamide | 1979-06-01 | Acrylamide produces a central-peripheral distal axonopathy when administered chronically. This is...more |
| T3D2575 | Tramadol | 27203-92-5 | Tramadol and its O-desmethyl metabolite (M1) are selective, weak OP3-receptor agonists. Opiate re...more |
| T3D2576 | Haloperidol | 52-86-8 | The precise mechanism whereby the therapeutic effects of haloperidol are produced is not known, b...more |
| T3D2577 | Varenicline | 249296-44-4 | Varenicline is an alpha-4 beta-2 neuronal nicotinic acetylcholine receptor partial agonist. The d...more |
| T3D2578 | Fluoroacetamide | 640-19-7 | Fluoroacetate produces its toxin action by inhibiting the citric acid cycle. The fluorine substit...more |
| T3D2580 | Mastoparan (Vespa tropica) | 72093-21-1 | Mastoparan causes varying types of exocytosis, depending on its location. In mast cells it causes...more |
| T3D2581 | Hongotoxin | 203526-59-4 | Hongotoxin inhibits voltage-gated potassium channels. (L1049) |
| T3D2582 | Maurocalcin | 269745-22-4 | Maurocalcin potently and reversibly modifies channel gating behaviour of the type 1 ryanodine rec...more |
| T3D2584 | Myotoxin (Crotalus viridis viridis) | 132821-30-8 | Myotoxins work by a non-enzymatic mechanism that leads to severe muscle necrosis, causing paralys...more |
| T3D2585 | Taipoxin | 52019-39-3 | Taipoxin causes a gradual reduction to complete stop of evoked and spontaneous release of acetylc...more |
| T3D2589 | Anthopleurin (Anthopleura xanthogrammica) | 600880-63-9 | Anthopleurin binds specifically to the voltage-gated sodium channel, thereby delaying its inactiv...more |
| T3D2590 | Calitoxin | 118354-83-9 | Calitoxin binds specifically to the voltage-gated sodium channel, thereby delaying its inactivati...more |
| T3D2592 | Edema factor | 921236-86-4 | After binding to a host cell surface receptor, PA is cleaved by membrane endoproteases of the fur...more |
| T3D2593 | Protective antigen | 643772-15-0 | After binding to a host cell surface receptor, PA is cleaved by membrane endoproteases of the fur...more |
| T3D2594 | Lethal factor | 159233-86-0 | After binding to a host cell surface receptor, PA is cleaved by membrane endoproteases of the fur...more |
| T3D2595 | Pertussis toxin | 70323-44-3 | After binding to the cell receptors, pertussis toxin (PTX) is endocytosed and the A moiety transl...more |
| T3D2596 | Bifunctional hemolysin/adenylate cyclase (Bordetella pertussis) | 566070-83-5 | After binding of the pertussis AC toxin to the cell, binding to calcium ions leads to the translo...more |
| T3D2597 | Toxin A (Clostridium difficile) | Not Available | Rho GTPases are activated by glucosylation (for example RhoA at Thr37). The toxins catalyze the t...more |
| T3D2598 | Toxin B (Clostridium difficile) | Not Available | Rho GTPases are activated by glucosylation (for example RhoA at Thr37). The toxins catalyze the t...more |
| T3D2599 | Alpha-toxin (Clostridium perfringens) | Not Available | Clostridium perfringens alpha toxin is a zinc metallophospholipase requiring zinc for activation....more |
| T3D2600 | Heat-labile enterotoxin (Escherichia coli) | Not Available | Through ADP-ribosylation of a G-protein, heat-labile enterotoxin stimulates adenylate cyclase lea...more |
| T3D2601 | Perfringolysin O | 71329-60-7 | Perfringolysin O binds to cholesterol on eukaryotic cell membranes, then forms oligomeric pores. ...more |
| T3D2602 | Tetanus toxin | 676570-37-9 | The bacterium synthesizes the tetanus toxin as a single 150kDa polypeptide chain (called the prog...more |
| T3D2605 | Listeriolysin O | 112627-82-4 | Listeriolysin O is a thiol-activated cholesterol-dependent pore forming toxin protein. LLO is sel...more |
| T3D2606 | Dermonecrotic toxin (Pasteurella multocida) | Not Available | Stimulation of several signalling pathways is induced by PMT. Most remarkable is a potent mitogen...more |
| T3D2607 | Exotoxin A (Pseudomonas aeruginosa) | Not Available | Pseudomonas exotoxin has exactly the same mechanism of action as the diphtheria toxin; it causes ...more |
| T3D2609 | Shiga toxin subunit A | Not Available | Shiga toxin causes the glycosidase cleavage of ribosomal eucaryotic 28S rRNA, resulting in inhibi...more |
| T3D2610 | Alpha-hemolysin | 94716-94-6 | Alpha-hemolysin consists mainly of beta-sheets forms heptameric units on the cellular membrane, p...more |
| T3D2611 | Beta-hemolysin | 143257-99-2 | Hemolysins consists mainly of beta-sheets forms heptameric units on the cellular membrane, produc...more |
| T3D2612 | Delta-hemolysin | 74838-20-3 | Hemolysins consists mainly of beta-sheets forms heptameric units on the cellular membrane, produc...more |
| T3D2613 | Leukocidin S | Not Available | Leukocidin S and leukocidin F act together as subunits, assembling in the membrane of host defens...more |
| T3D2614 | Leukocidin F | 147096-70-6 | Leukocidin S and leukocidin F act together as subunits, assembling in the membrane of host defens...more |
| T3D2618 | Enterotoxin type A | Not Available | The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of...more |
| T3D2619 | Enterotoxin type B | Not Available | The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of...more |
| T3D2620 | Pneumolysin | Not Available | Pneumolysin binds to cholesterol the undergoes oligomerization and membrane pore formation. Pneum...more |
| T3D2622 | Streptolysin O (Streptococcus pyogenes) | 98072-47-0 | Streptolysin O binds to cholesterol on eukaryotic cell membranes, then is able to lyse them. (T170) |
| T3D2623 | Cholera toxin | 9012-63-9 | The effect is dependent on a specific receptor, monosialosyl ganglioside (GM1 ganglioside) presen...more |
| T3D2624 | Melittin (Apis mellifera) | 20449-79-0 | Melittin has strong haemolytic activity. It integrates into cell membranes and has multiple effec...more |
| T3D2625 | Lopap | Not Available | Lopap activates thrombin by cleavage of prothrombin, causing thrombus formation, fibrinogen deple...more |
| T3D2626 | alpha-Agatoxin | 128549-96-2 | alpha-Agatoxins block the glutamate-activated receptor channels in the neuronal postsynaptic term...more |
| T3D2627 | mu-Agatoxin | 120500-28-9 | mu-Agatoxins modify presynaptic voltage-activated sodium channels in the neuromuscular joints of ...more |
| T3D2628 | kappa-Atracotoxin (Hadronyche versuta) | Not Available | kappa-Atracotoxins inhibit insect voltage-gated potassium channels. (T170, L1812) |
| T3D2629 | Hanatoxin | 170780-01-5 | Hanatoxin inhibits voltage-gated potassium channels by altering the gating energetics, which it d...more |
| T3D2630 | Sphingomyelinase D (Loxosceles intermedia) | 9031-54-3 | Sphingomyelinase D catalyzes the hydrolysis of sphingomyelin, inducing complement-dependent haemo...more |
| T3D2631 | Heteroscodratoxin | Not Available | Heteroscodratoxin inhibits voltage-gated potassium channels by binding to the extracellular linke...more |
| T3D2633 | Acanthophin | 126601-49-8 | Acanthophin produces peripheral paralysis by blocking neuromuscular transmission at the postsynap...more |
| T3D2635 | Erabutoxin | 59536-69-5 | Erabutoxin binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), and w...more |
| T3D2636 | Disintegrin echistatin (Echis carinatus) | Not Available | Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They ...more |
| T3D2637 | Nigroxin | 9001-84-7 | Nigroxin is myotoxic. (T170) |
| T3D2638 | Notexin | 37233-96-4 | Notexin is myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release fro...more |
| T3D2639 | Ohanin | Not Available | Ohanin is extremely neurotoxic, cardiotoxic, and cytotoxic. (L1102) |
| T3D2640 | Pseudechetoxin | Not Available | Pseudechetoxin blocks olfactory and retinal cyclic nucleotide-gated (CNG) ion channel currents. I...more |
| T3D2642 | Viperotoxin | Not Available | Viperotoxin is a presynaptic neurotoxin. (T170) |
| T3D2643 | Vipoxin | Not Available | Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotoni...more |
| T3D2646 | Hydralysin (Chlorohydra viridissima) | Not Available | Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activit...more |
| T3D2647 | Stonustoxin | Not Available | Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. I...more |
| T3D2648 | Neoverrucotoxin | Not Available | Neoverrucotoxin has hemolytic activities. (T170) |
| T3D2649 | Box jellyfish toxin (Chironex fleckeri) | Not Available | Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting...more |
| T3D2656 | omega-Conotoxin (Conus striatus) | Not Available | omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent c...more |
| T3D2657 | alpha-Conotoxin (Conus geographus) | Not Available | alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine recept...more |
| T3D2658 | delta-Conotoxin (Conus striatus) | Not Available | delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) |
| T3D2659 | kappa-Conotoxin (Conus purpurascens) | Not Available | kappa-Conotoxins inhibit potassium channels. (L1107) |
| T3D2660 | mu-Conotoxin (Conus purpurascens) | Not Available | mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) |
| T3D2661 | Contryphan (Conus ventricosus) | Not Available | Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) |
| T3D2665 | Pamidronate | 40391-99-9 | The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to c...more |
| T3D2666 | Alendronic acid | 66376-36-1 | The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, whic...more |
| T3D2667 | Ibandronate | 114084-78-5 | The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, whic...more |
| T3D2671 | Rituximab | 174722-31-7 | Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune e...more |
| T3D2672 | Azaspiracid | 214899-21-5 | Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigarg...more |
| T3D2673 | Zaleplon | 151319-34-5 | Zaleplon exerts its action through subunit modulation of the GABABZ receptor chloride channel mac...more |
| T3D2675 | Linezolid | 165800-03-3 | Linezolid targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitoch...more |
| T3D2676 | Methadone | 76-99-3 | Methadone is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively simil...more |
| T3D2677 | Aripiprazole | 129722-12-9 | Aripiprazole's antipsychotic activity is likely due to a combination of antagonism at D2 receptor...more |
| T3D2679 | Nitrofurantoin | 67-20-9 | Nitrofurantoin is activated by bacterial flavoproteins (nitrofuran reductase) to active reduced r...more |
| T3D2690 | Biotin | 58-85-5 | Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix c...more |
| T3D2696 | Thiamine | 59-43-8 | It is thought that the mechanism of action of thiamine on endothelial cells is related to a reduc...more |
| T3D2698 | Folic acid | 59-30-3 | Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetra...more |
| T3D2705 | Fluvoxamine | 54739-18-3 | The exact mechanism of action of fluvoxamine has not been fully determined, but appears to be lin...more |
| T3D2706 | Amphetamine | 300-62-9 | Amphetamines stimulate the release of norepinephrine from central adrenergic receptors. At higher...more |
| T3D2707 | Lorazepam | 846-49-1 | Lorazepam binds to an allosteric site on GABA-A receptors, which are pentameric ionotropic recept...more |
| T3D2709 | Phentermine | 122-09-8 | Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a par...more |
| T3D2711 | Fluconazole | 86386-73-4 | Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanos...more |
| T3D2713 | Reserpine | 50-55-5 | Reserpine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the se...more |
| T3D2715 | Citalopram | 59729-33-8 | The antidepressant, antiobsessive-compulsive, and antibulimic actions of citalopram are presumed ...more |
| T3D2719 | Temazepam | 846-50-4 | Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation...more |
| T3D2720 | Reboxetine | 98769-81-4 | Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake...more |
| T3D2721 | Butabarbital | 125-40-6 | Butabarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more |
| T3D2722 | Oxiconazole | 64211-46-7 | Oxiconazole inhibits ergosterol biosynthesis, which is required for cytoplasmic membrane integrit...more |
| T3D2724 | Benzatropine | 86-13-5 | Benztropine is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discrim...more |
| T3D2726 | Methysergide | 361-37-5 | Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 s...more |
| T3D2727 | Cabergoline | 81409-90-7 | Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 s...more |
| T3D2728 | Phenytoin | 57-41-0 | Phenytoin acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure a...more |
| T3D2729 | Clotrimazole | 23593-75-1 | Clotrimazole interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanos...more |
| T3D2731 | Ropinirole | 91374-21-9 | Ropinirole binds the dopamine receptors D3 and D2. Although the precise mechanism of action of ro...more |
| T3D2735 | Lidocaine | 137-58-6 | Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initia...more |
| T3D2736 | Venlafaxine | 93413-69-5 | The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the it...more |
| T3D2737 | Atomoxetine | 82248-59-7 | The precise mechanism by which atomoxetine produces its therapeutic effects in Attention-Deficit/...more |
| T3D2738 | Bleomycin | 11056-06-7 | It has been suggested that bleomycin induces sensitivity to oxygen toxicity and recent studies su...more |
| T3D2740 | Morphine | 57-27-2 | The precise mechanism of the analgesic action of morphine is unknown. However, specific CNS opiat...more |
| T3D2741 | Ropivacaine | 84057-95-4 | Local anesthetics such as Ropivacaine block the generation and the conduction of nerve impulses, ...more |
| T3D2742 | Bupivacaine | 2180-92-9 | Bupivacaine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibi...more |
| T3D2743 | Mitomycin | 50-07-7 | Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to D...more |
| T3D2745 | Pentobarbital | 76-74-4 | Pentobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recept...more |
| T3D2748 | Zolmitriptan | 139264-17-8 | Zolmitriptan binds with high affinity to human 5-HT1B and 5-HT1D receptors leading to cranial blo...more |
| T3D2749 | Codeine | 76-57-3 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
| T3D2750 | Dihydroergotamine | 6190-39-2 | Two theories have been proposed to explain the efficacy of 5-HT1D receptor agonists in migraine: ...more |
| T3D2752 | Hydromorphone | 466-99-9 | Hydromorphone is a narcotic analgesic; its principal therapeutic effect is relief of pain. Hydrom...more |
| T3D2753 | Indomethacin | 53-86-1 | Antiinflammatory effects of Indomethacin are believed to be due to inhibition of cylooxygenase in...more |
| T3D2754 | Olanzapine | 132539-06-1 | Olanzapine's antipsychotic activity is likely due to a combination of antagonism at D2 receptors ...more |
| T3D2755 | Metixene | 4969-02-2 | Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhi...more |
| T3D2756 | Cetirizine | 83881-51-0 | Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface,...more |
| T3D2757 | Terfenadine | 50679-08-8 | Terfenadine competes with histamine for binding at H1-receptor sites in the GI tract, uterus, lar...more |
| T3D2758 | Diltiazem | 42399-41-7 | Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering w...more |
| T3D2759 | Protriptyline | 438-60-8 | Protriptyline acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). |
| T3D2760 | Trimethadione | 127-48-0 | Dione anticonvulsants reduce T-type calcium currents in thalamic neurons, including thalamic rela...more |
| T3D2763 | Anidulafungin | 166663-25-8 | Anidulafungin is a semi-synthetic echinocandin with antifungal activity. Anidulafungin inhibits g...more |
| T3D2764 | Clozapine | 5786-21-0 | The mechanism of action of Clozapine, as with other drugs used to treat schizophrenia, is unknown...more |
| T3D2767 | Mirtazapine | 61337-67-5 | Mirtazapine acts as an antagonist at central pre-synaptic alpha(2)-receptors, inhibiting negative...more |
| T3D2770 | Trihexyphenidyl | 144-11-6 | Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to dis...more |
| T3D2771 | Dexrazoxane | 24584-09-6 | The mechanism by which dexrazoxane exerts its cardioprotective activity is not fully understood. ...more |
| T3D2772 | Tacrine | 321-64-2 | Tacrine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor ...more |
| T3D2773 | Procyclidine | 77-37-2 | The mechanism of action is unknown. It is thought that Procyclidine acts by blocking central chol...more |
| T3D2779 | Loxapine | 1977-10-2 | Loxapine is a dopamine antagonist, and also a serotonin 5-HT2 blocker. The exact mode of action o...more |
| T3D2783 | Pramipexole | 104632-26-0 | The precise mechanism of action of Pramipexole as a treatment for Parkinson's disease is unknown,...more |
| T3D2784 | Secobarbital | 76-73-3 | Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more |
| T3D2786 | Methylphenidate | 113-45-1 | Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transpo...more |
| T3D2787 | Zolpidem | 82626-48-0 | Zolpidem modulates the alpha-subunit, known as the benzodiazepine receptor, within the GABAA rece...more |
| T3D2788 | Streptozocin | 18883-66-4 | Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-produc...more |
| T3D2789 | Prochlorperazine | 58-38-8 | The mechanism of action of prochlorperazine has not been fully determined, but may be primarily r...more |
| T3D2790 | Cyproheptadine | 129-03-3 | Cyproheptadine competes with free histamine for binding at HA-receptor sites. This antagonizes th...more |
| T3D2791 | Epirubicin | 56420-45-2 | Epirubicin has antimitotic and cytotoxic activity. It inhibits nucleic acid (DNA and RNA) and pro...more |
| T3D2795 | Meperidine | 57-42-1 | Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Me...more |
| T3D2796 | Loratadine | 79794-75-5 | Loratadine competes with free histamine and exhibits specific, selective peripheral H1 antagonist...more |
| T3D2797 | Imipramine | 50-49-7 | Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and ...more |
| T3D2798 | Metharbital | 50-11-3 | Metharbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor...more |
| T3D2800 | Quinine | 130-95-0 | The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs...more |
| T3D2802 | Fluoxetine | 54910-89-3 | Fluoxetine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibit...more |
| T3D2803 | Methohexital | 151-83-7 | Methohexital binds at a distinct binding site associated with a Cl- ionopore at the GABAA recepto...more |
| T3D2804 | Chlordiazepoxide | 58-25-3 | Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor ...more |
| T3D2805 | Duloxetine | 136434-34-9 | Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a less pot...more |
| T3D2806 | Chlorpromazine | 50-53-3 | Chlorpromazine acts as an antagonist (blocking agent) on different postsysnaptic receptors -on do...more |
| T3D2807 | Buspirone | 36505-84-7 | Buspirone binds to 5-HT type 1A serotonin receptors on presynaptic neurons in the dorsal raphe an...more |
| T3D2808 | Entacapone | 130929-57-6 | The mechanism of action of entacapone is believed to be through its ability to inhibit COMT in pe...more |
| T3D2809 | Oxycodone | 76-42-6 | Oxycodone acts as a weak agonist at mu, kappa, and delta opioid receptors within the central nerv...more |
| T3D2810 | Cimetidine | 51481-61-9 | Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal ce...more |
| T3D2813 | Triflupromazine | 146-54-3 | Triflupromazine binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. T...more |
| T3D2815 | Dextromethorphan | 125-71-3 | Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamat...more |
| T3D2818 | Nortriptyline | 72-69-5 | It is believed that nortriptyline either inhibits the reuptake of the neurotransmitter serotonin ...more |
| T3D2819 | Amoxapine | 14028-44-5 | Amoxapine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). |
| T3D2820 | Pyridostigmine | 155-97-5 | Pyridostigmine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inh...more |
| T3D2822 | Pentostatin | 53910-25-1 | Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest act...more |
| T3D2823 | Hydroxyzine | 68-88-2 | Hydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface...more |
| T3D2825 | Benzthiazide | 91-33-8 | As a diuretic, benzthiazide inhibits active chloride reabsorption at the early distal tubule via ...more |
| T3D2826 | Carbamazepine | 298-46-4 | Carbamazepine inhibits sustained repetitive firing by blocking use-dependent sodium channels. Pai...more |
| T3D2829 | Clonidine | 4205-90-7 | Clonidine acts as an agonist at presynaptic alpha(2)-receptors in the nucleus tractus solitarius ...more |
| T3D2830 | Mazindol | 22232-71-9 | Although the mechanism of action of the sympathomimetics in the treatment of obesity is not fully...more |
| T3D2834 | Ethosuximide | 77-67-8 | Binds to T-type voltage sensitive calcium channels. Voltage-sensitive calcium channels (VSCC) med...more |
| T3D2835 | Thiopental | 76-75-5 | Thiopental binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor,...more |
| T3D2836 | Cisapride | 81098-60-4 | Cisapride acts through the stimulation of the serotonin 5-HT4 receptors which increases acetylcho...more |
| T3D2837 | Butorphanol | 42408-82-2 | The exact mechanism of action is unknown, but is believed to interact with an opiate receptor sit...more |
| T3D2838 | Rifabutin | 72559-06-9 | Rifabutin acts via the inhibition of DNA-dependent RNA polymerase in gram-positive and some gram-...more |
| T3D2839 | Paramethadione | 115-67-3 | Dione anticonvulsants such as paramethadione reduce T-type calcium currents in thalamic neurons (...more |
| T3D2840 | Fluphenazine | 69-23-8 | Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depres...more |
| T3D2842 | Clorazepate | 23887-31-2 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D2844 | Astemizole | 68844-77-9 | Astemizole competes with histamine for binding at H1-receptor sites in the GI tract, uterus, larg...more |
| T3D2847 | Nystatin | 1400-61-9 | Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion ...more |
| T3D2848 | Propoxyphene | 469-62-5 | Propoxyphene acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nerv...more |
| T3D2849 | Pteroyl-D-glutamic acid | 1492-18-8 | As leucovorin is a derivative of folic acid, it can be used to increase levels of folic acid unde...more |
| T3D2850 | Pentazocine | 359-83-1 | The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competi...more |
| T3D2852 | Trazodone | 19794-93-5 | Trazodone binds at 5-HT2 receptor, it acts as a serotonin agonist at high doses and a serotonin a...more |
| T3D2853 | Acamprosate | 77337-76-9 | The mechanism of action of acamprosate in maintenance of alcohol abstinence is not completely und...more |
| T3D2855 | Nafarelin | 76932-56-4 | Like GnRH, initial or intermittent administration of nafarelin stimulates release of the gonadotr...more |
| T3D2856 | Sumatriptan | 103628-46-2 | The 5-HT1B and 5-HT1D receptors function as autoreceptors, which inhibit the firing of serotonin ...more |
| T3D2857 | Galantamine | 357-70-0 | Galantamine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibi...more |
| T3D2858 | Thioridazine | 50-52-2 | Thioridazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; blocks...more |
| T3D2860 | Flurazepam | 17617-23-1 | Benzodiazepines bind nonspecifically to bezodiazepine receptors BNZ1, which mediates sleep, and B...more |
| T3D2861 | Daunorubicin | 20830-81-3 | Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of ac...more |
| T3D2862 | Tizanidine | 51322-75-9 | Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agoni...more |
| T3D2863 | Amprenavir | 161814-49-9 | Amprenavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polypr...more |
| T3D2864 | Naltrexone | 16590-41-3 | Naltrexone is a pure opiate antagonist and has little or no agonist activity. The mechanism of ac...more |
| T3D2865 | Sufentanil | 56030-54-7 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
| T3D2867 | Apomorphine | 41372-20-7 | The precise mechanism of action of apomorphine as a treatment for Parkinson's disease is unknown,...more |
| T3D2868 | Paroxetine | 61869-08-7 | Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine ...more |
| T3D2869 | Procaine | 59-46-1 | Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neu...more |
| T3D2870 | Trimipramine | 739-71-9 | Trimipramine's mechanism of action differs from other tricyclic antidepressants. Trimipramine act...more |
| T3D2871 | Risperidone | 106266-06-2 | Blockade of dopaminergic D2 receptors in the limbic system alleviates positive symptoms of schizo...more |
| T3D2874 | Meclizine | 569-65-3 | Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic...more |
| T3D2875 | Riluzole | 1744-22-5 | The mode of action of riluzole is unknown. Its pharmacological properties include the following, ...more |
| T3D2876 | Modafinil | 68693-11-8 | The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the ...more |
| T3D2877 | Scopolamine | 51-34-3 | Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the p...more |
| T3D2881 | Tranylcypromine | 155-09-9 | Tranylcypromine irreversibly and nonselectively inhibits monoamine oxidase (MAO). Within neurons,...more |
| T3D2883 | Ethotoin | 86-35-1 | The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to...more |
| T3D2886 | Olopatadine | 113806-05-6 | Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 receptor. This ...more |
| T3D2887 | Oxcarbazepine | 28721-07-5 | The exact mechanism by which oxcarbazepine exerts its anticonvulsant effect is unknown. It is kno...more |
| T3D2888 | Propiomazine | 362-29-8 | Propiomazine is an antagonist at types 1, 2, and 4 dopamine receptors, serotonin (5-HT) receptor ...more |
| T3D2889 | Phenelzine | 51-71-8 | Although the exact mechanism of action has not been determined, it appears that the irreversible,...more |
| T3D2893 | Halazepam | 23092-17-3 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D2894 | Alfentanil | 71195-58-9 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
| T3D2896 | Proparacaine | 499-67-2 | The exact mechanism whereby proparacaine and other local anesthetics influence the permeability o...more |
| T3D2897 | Biperiden | 514-65-8 | Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhi...more |
| T3D2898 | Fentanyl | 437-38-7 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
| T3D2899 | Meloxicam | 71125-38-7 | Anti-inflammatory effects of meloxicam are believed to be due to inhibition of prostaglandin synt...more |
| T3D2903 | Diazepam | 439-14-5 | Benzodiazepines bind nonspecifically to benzodiazepine receptors which mediate sleep, affects mus...more |
| T3D2904 | Phenmetrazine | 134-49-6 | Phenmetrazine is thought to block the reuptake of norepinephrine and dopamine into the presynapti...more |
| T3D2905 | Trifluoperazine | 117-89-5 | Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; dep...more |
| T3D2907 | Mifepristone | 84371-65-3 | Mifepristone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhib...more |
| T3D2908 | Progabide | 62666-20-0 | Progabide binds to both GABAA and GABAB receptors located on the terminals of primary afferent fi...more |
| T3D2909 | Oxazepam | 604-75-1 | Similar to other benzodiazepines, oxazepam exerts its anxiolytic effects by potentiating the effe...more |
| T3D2910 | Donepezil | 120014-06-4 | Donepezil is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more |
| T3D2911 | Nalbuphine | 20594-83-6 | Receptor studies show that nalbuphine exerts its action via binding to mu, kappa, and delta recep...more |
| T3D2913 | Perphenazine | 58-39-9 | Binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of ...more |
| T3D2914 | Levorphanol | 77-07-6 | Like other mu-agonist opioids it is believed to act at receptors in the periventricular and peria...more |
| T3D2919 | Benzphetamine | 156-08-1 | Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of...more |
| T3D2920 | Flupenthixol | 2709-56-0 | Flupenthixol is a thioxanthene antipsychotic. The mechanism of action of Flupenthixol is not comp...more |
| T3D2921 | Sirolimus | 53123-88-9 | Sirolimus inhibits T lymphocyte activation and proliferation that occurs in response to antigenic...more |
| T3D2924 | Methdilazine | 1982-37-2 | Methdilazine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, ...more |
| T3D2925 | Ondansetron | 99614-02-5 | Ondansetron is a selective serotonin 5-HT3 receptor antagonist. The antiemetic activity of the dr...more |
| T3D2926 | Tiagabine | 115103-54-3 | Though the exact mechanism by which Tiagabine exerts its effect on the human body is unknown, it ...more |
| T3D2927 | Cocaine | 50-36-2 | Cocaine produces anesthesia by inhibiting excitation of nerve endings or by blocking conduction i...more |
| T3D2929 | Anileridine | 144-14-9 | Opiate receptors are coupled with G-protein receptors and function as both positive and negative ...more |
| T3D2931 | Almotriptan | 181183-52-8 | Almotriptan binds with high affinity to human 5-HT1B and 5-HT1D receptors leading to cranial bloo...more |
| T3D2932 | Buprenorphine | 52485-79-7 | Buprenorphine's analgesic effect is due to partial agonist activity at mu-opioid receptors. Bupre...more |
| T3D2933 | Mesoridazine | 5588-33-0 | Based upon animal studies, mesoridazine, as with other phenothiazines, acts indirectly on reticul...more |
| T3D2934 | Maprotiline | 10262-69-8 | Maprotiline exerts its antidepressant action by inhibition of presynaptic uptake of catecholamine...more |
| T3D2935 | Diethylpropion | 90-84-6 | Diethylpropion is an amphetamine that stimulates neurons to release or maintain high levels of a ...more |
| T3D2937 | Felbamate | 25451-15-4 | The mechanism by which felbamate exerts its anticonvulsant activity is unknown, but in animal tes...more |
| T3D2938 | Fexofenadine | 83799-24-0 | Like other H1-blockers, Fexofenadine competes with free histamine for binding at H1-receptors in ...more |
| T3D2939 | Naratriptan | 121679-13-8 | Three distinct pharmacological actions have been implicated in the antimigraine effect of the tri...more |
| T3D2940 | Rizatriptan | 145202-66-0 | Three distinct pharmacological actions have been implicated in the antimigraine effect of the tri...more |
| T3D2941 | Hydrocodone | 125-29-1 | Hydrocodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervo...more |
| T3D2942 | Mepivacaine | 96-88-8 | Local anesthetics block the generation and the conduction of nerve impulses, presumably by increa...more |
| T3D2951 | Neomycin | 1404-04-2 | Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. ...more |
| T3D2952 | Gabapentin | 60142-96-3 | Gabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium cha...more |
| T3D2953 | Doxorubicin | 23214-92-8 | Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of act...more |
| T3D2954 | Frovatriptan | 158747-02-5 | Three distinct pharmacological actions have been implicated in the antimigraine effect of the tri...more |
| T3D2955 | Levobupivacaine | 27262-47-1 | Levobupivacaine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase in...more |
| T3D2956 | Tioconazole | 65899-73-2 | Tioconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol t...more |
| T3D2957 | Balsalazide | 80573-04-2 | The mechanism of action of 5-aminosalicylic acid is unknown, but appears exert its anti-inflammat...more |
| T3D2958 | Bethanechol | 674-38-4 | Bethanechol directly stimulates cholinergic receptors in the parasympathetic nervous system while...more |
| T3D2961 | Ketoconazole | 65277-42-1 | Ketoconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the convers...more |
| T3D2963 | Ethinamate | 126-52-3 | The mechanism of action is not known. However, studies have shown that ethinamate inhibits carbon...more |
| T3D2965 | Selegiline | 14611-51-9 | Although the mechanisms for selegiline's beneficial action in the treatment of Parkinson's diseas...more |
| T3D2966 | Carphenazine | 2622-30-2 | A yellow, powdered, phenothiazine antipsychotic agent used in the treatment of acute or chronic s...more |
| T3D2967 | Memantine | 19982-08-2 | Memantine exerts its action through uncompetitive NMDA receptor antagonism, binding preferentiall...more |
| T3D2968 | Gatifloxacin | 112811-59-3 | The bactericidal action of Gatifloxacin results from inhibition of the enzymes topoisomerase II (...more |
| T3D2969 | Rifampin | 13292-46-1 | Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA...more |
| T3D2972 | Melatonin | 73-31-4 | Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts ...more |
| T3D2973 | Clonazepam | 1622-61-3 | Allosteric interactions between central benzodiazepine receptors and gamma-aminobutyric acid (GAB...more |
| T3D2975 | Perhexiline | 6621-47-2 | Perhexiline binds to the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1 and CPT-2. I...more |
| T3D2976 | Diphenhydramine | 58-73-1 | Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes t...more |
| T3D2977 | Vigabatrin | 60643-86-9 | Vigabatrin increases brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurot...more |
| T3D2978 | Diphenoxylate | 915-30-0 | Diphenoxylate is an opiate receptor agonists that stimulate mu receptors in GI to decrease the pe...more |
| T3D2980 | Benzocaine | 94-09-7 | Benzocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreas...more |
| T3D2983 | Flucytosine | 2022-85-7 | Although the exact mode of action is unknown, it has been proposed that flucytosine acts directly...more |
| T3D2984 | Pimozide | 2062-78-4 | The ability of pimozide to suppress motor and phonic tics in Tourette's Disorder is thought to be...more |
| T3D2985 | Sertraline | 79617-96-2 | The exact mechanism of action sertraline is not fully known, but the drug appears to selectively ...more |
| T3D2986 | Sibutramine | 106650-56-0 | Sibutramine produces its therapeutic effects by inhibition of norepinephrine (NE), serotonin (5-h...more |
| T3D2987 | Methyprylon | 125-64-4 | Methyprylon binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor...more |
| T3D2988 | Miconazole | 22916-47-8 | Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanost...more |
| T3D2989 | Chlorpheniramine | 132-22-9 | Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histami...more |
| T3D2990 | Phenacemide | 63-98-9 | Phenacemide binds to and blocks neuronal sodium channels or voltage sensitive calcium channels. T...more |
| T3D2991 | Ambenonium | 7648-98-8 | Ambenonium is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibit...more |
| T3D2992 | Econazole | 27220-47-9 | Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanoste...more |
| T3D2993 | Doxepin | 1668-19-5 | The mechanism of action of doxepin is not completely understood. It is thought that like amitript...more |
| T3D2995 | Nefazodone | 83366-66-9 | Within the serotonergic system, nefazodone acts as an antagonist at type 2 serotonin (5-HT2) post...more |
| T3D2996 | Desipramine | 50-47-5 | Desipramine is a tricyclic antidepressant (TCA) that selectively blocks reuptake of norepinephrin...more |
| T3D2997 | Sertaconazole | 99592-32-2 | Sertaconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lan...more |
| T3D2999 | Bupropion | 34841-39-9 | Bupropion selectively inhibits the neuronal reuptake of dopamine, norepinephrine, and serotonin; ...more |
| T3D3000 | Trimetrexate | 52128-35-5 | In vitro studies have shown that trimetrexate is a competitive inhibitor of dihydrofolate reducta...more |
| T3D3003 | Chloroprocaine | 133-16-4 | Chloroprocaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in t...more |
| T3D3004 | Moclobemide | 71320-77-9 | The mechanism of action of moclobemide involves the selective, reversible inhibition of MAO-A. Th...more |
| T3D3005 | Orphenadrine | 83-98-7 | Orphenadrine binds and inhibits both histamine H1 receptors and NMDA receptors. It restores the m...more |
| T3D3006 | Phenobarbital | 50-06-6 | Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of ele...more |
| T3D3007 | Escitalopram | 128196-01-0 | The antidepressant, antiobsessive-compulsive, and antibulimic actions of escitalopram are presume...more |
| T3D3009 | Chlormezanone | 80-77-3 | Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA r...more |
| T3D3011 | Pergolide | 66104-22-1 | The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi prote...more |
| T3D3014 | Dexfenfluramine | 3239-44-9 | Dexfenfluramine binds to the serotonin reuptake pump. This causes inhbition of serotonin reuptake...more |
| T3D3015 | Oxymorphone | 76-41-5 | Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discr...more |
| T3D3016 | Zopiclone | 43200-80-2 | Zopiclone exerts its action by binding on the benzodiazepine receptor complex and modulation of t...more |
| T3D3017 | Bromocriptine | 25614-03-3 | The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi prote...more |
| T3D3018 | Rifapentine | 61379-65-5 | Rifapentine has shown higher bacteriostatic and bactericidal activities especially against intrac...more |
| T3D3019 | Levetiracetam | 102767-28-2 | The precise mechanism(s) by which levetiracetam exerts its antiepileptic effect is unknown. The a...more |
| T3D3020 | Mitoxantrone | 65271-80-9 | Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hyd...more |
| T3D3025 | Ketamine | 6740-88-1 | Ketamine has several clinically useful properties, including analgesia and less cardiorespiratory...more |
| T3D3027 | Levomethadyl Acetate | 1477-40-3 | Opiate receptors (Mu, Kappa, Delta) are coupled with G-protein receptors and function as both pos...more |
| T3D3028 | L-Dopa | 59-92-7 | Striatal dopamine levels in symptomatic Parkinson's disease are decreased by 60 to 80%, striatal ...more |
| T3D3030 | Bromodiphenhydramine | 118-23-0 | Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. This antagoni...more |
| T3D3031 | Chlorprothixene | 113-59-7 | Chlorprothixene blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; dep...more |
| T3D3032 | Clomipramine | 303-49-1 | Clomipramine is a strong, but not completely selective serotonin reuptake inhibitor (SRI), as the...more |
| T3D3033 | Isocarboxazid | 59-63-2 | Isocarboxazid works by irreversibly blocking the action of a chemical substance known as monoamin...more |
| T3D3035 | Posaconazole | 171228-49-2 | As a triazole antifungal agent, posaconazole exerts its antifungal activity through blockage of t...more |
| T3D3036 | Fosphenytoin | 93390-81-9 | Fosphenytoin is a prodrug of phenytoin and accordingly, its anticonvulsant effects are attributab...more |
| T3D3038 | Butethal | 77-28-1 | Butethal binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, i...more |
| T3D3039 | Hexobarbital | 56-29-1 | Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A recept...more |
| T3D3040 | Ephedrine | 299-42-3 | Ephedrine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more |
| T3D3041 | Methotrimeprazine | 60-99-1 | Methotrimeprazine's antipsychotic effect is largely due to its antagonism of dopamine receptors i...more |
| T3D3046 | Fencamfamine | 1209-98-9 | Fencamfamine acts as an indirect dopamine agonist. It releases dopamine by a similar mechanism to...more |
| T3D3047 | Flunitrazepam | 1622-62-4 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D3048 | Bromazepam | 1812-30-2 | Bromazepam binds to the GABA receptor GABAA, causing a conformational change and increasing inhib...more |
| T3D3049 | Clotiazepam | 33671-46-4 | Clotiazepam acts at the benzodiazepine receptors (BZD). This agonizes the action of GABA, increas...more |
| T3D3051 | Dextroamphetamine | 51-64-9 | The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinep...more |
| T3D3052 | Methamphetamine | 537-46-2 | Methamphetamine enters the brain and triggers a cascading release of norepinephrine, dopamine and...more |
| T3D3054 | Prazepam | 2955-38-6 | Prazepam is believed to stimulate GABA receptors in the ascending reticular activating system. Si...more |
| T3D3055 | Quazepam | 36735-22-5 | Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation...more |
| T3D3056 | Cinolazepam | 75696-02-5 | Cinolazepam binds to central benzodiazepine receptors which interact allosterically with GABA rec...more |
| T3D3057 | Nitrazepam | 146-22-5 | Nitrazepam belongs to a group of medicines called benzodiazepines. It acts on benzodiazepine rece...more |
| T3D3060 | Phenindamine | 82-88-2 | Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor s...more |
| T3D3064 | Chlophedianol | 791-35-5 | Suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain. |
| T3D3066 | Bepotastine | 125602-71-3 | Because of a type 1 hypersensitivity reaction cascade that is triggered by antigen exposure, alle...more |
| T3D3067 | Vapreotide | 103222-11-3 | The exact mechanism of action is unknown, although one study has provided in vitro and in vivo ev...more |
| T3D3068 | Silver sulfadiazine | 22199-08-2 | Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemica...more |
| T3D3069 | Methsuximide | 77-41-8 | Methsuximide suppresses the paroxysmal three cycle per second spike and wave activity associated ...more |
| T3D3070 | Abrin-a | 53597-23-2 | Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attach...more |
| T3D3071 | Abrin-b | Not Available | Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attach...more |
| T3D3072 | Abrin-c | 53597-24-3 | Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attach...more |
| T3D3073 | Abrin-d | 1393-62-0 | Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attach...more |
| T3D3075 | Brucine | 357-57-3 | Brucine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligan...more |
| T3D3077 | Delphinine | 561-07-9 | Delphinine acts as an allosteric modulator of voltage-gated sodium channels. (L1234) |
| T3D3078 | Aconitine | 302-27-2 | Aconitine opens voltage-gated sodium channed in the heart and other tissues. (L1235) |
| T3D3079 | Djenkolic acid | 498-59-9 | The toxicity of djenkolic acid in humans arises from its poor solubility under acidic conditions ...more |
| T3D3082 | beta-Methylamino-L-alanine | 15920-93-1 | BMAA may cause neurotoxic effects by damaging cells (such as neurons) in the motor cortex and spi...more |
| T3D3085 | Capsaicin | 404-86-4 | The burning and painful sensations associated with capsaicin result from its chemical interaction...more |
| T3D3086 | Strychnine | 57-24-9 | Strychnine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a li...more |
| T3D3087 | Swainsonine | 72741-87-8 | Swainsonine inhibits the activity of glycoside hydrolases, especially N-linked glycosylation. Inh...more |
| T3D3088 | Thionin (Pyrularia pubera) | Not Available | Thionins are thought to attack the cell membrane and render it permeable. This results in the inh...more |
| T3D3095 | Hyoscyamine | 101-31-5 | Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the acti...more |
| T3D3096 | D-Hyoscyamine | 13269-35-7 | Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the acti...more |
| T3D3097 | Tubocurarine | 6989-98-6 | Tubocurarine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhib...more |
| T3D3098 | Alcuronium | 23214-96-2 | Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotin...more |
| T3D3099 | Toxiferine | 6888-23-9 | Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotin...more |
| T3D3108 | Anabasine | 13078-04-1 | Anabasine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibito...more |
| T3D3121 | Diphtheria toxin (Corynephage omega) | Not Available | Diphtheria toxin consists of a single polypeptide. Proteolysis yields two fragments (A and B) whi...more |
| T3D3123 | Botulinum neurotoxin type E | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3124 | Botulinum neurotoxin type F | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3125 | Botulinum neurotoxin type B | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3126 | Botulinum neurotoxin type D | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3127 | Botulinum neurotoxin type A | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3128 | Botulinum neurotoxin type C1 | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3129 | Shiga toxin subunit B | 75757-64-1 | Shiga toxin causes the glycosidase cleavage of ribosomal eucaryotic 28S rRNA, resulting in inhibi...more |
| T3D3209 | Diazenedicarboxamide | 123-77-3 | Azodicarbonamide prevents the progression of human CD4+ T lymphocytes into the G1 phase of the ce...more |
| T3D3474 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | 28289-54-5 | MPTP itself is not toxic, and as a lipophilic compound can cross the blood-brain barrier. Once in...more |
| T3D3476 | Albendazole | 54965-21-8 | Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by b...more |
| T3D3478 | Methyldopa | 555-29-3 | Although the mechanism of action has yet to be conclusively demonstrated, the antihypertensive ef...more |
| T3D3479 | Amatoxin (Amanita phalloides) | 58250-15-0 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3480 | Atenolol | 29122-68-7 | Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines ...more |
| T3D3487 | Brimonidine | 59803-98-4 | Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hyp...more |
| T3D3491 | Carisoprodol | 78-44-4 | Carisoprodol is a central nervous system depressant that acts as a sedative and skeletal muscle r...more |
| T3D3492 | Cephalosporin | 97519-39-6 | Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacteria...more |
| T3D3495 | Ciprofloxacin | 85721-33-1 | The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II ...more |
| T3D3497 | Clindamycin | 18323-44-9 | Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosom...more |
| T3D3498 | Cyclosporin | 59865-13-3 | Cyclosporine binds to cyclophilin. The complex then inhibits calcineurin which is normally respon...more |
| T3D3499 | Darifenacin | 133099-04-4 | Darifenacin selectively antagonizes the muscarinic M3 receptor. M3 receptors are involved in cont...more |
| T3D3501 | Docetaxel | 114977-28-5 | Docetaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicin...more |
| T3D3507 | Capecitabine | 154361-50-9 | Capecitabine is a prodrug that is selectively tumour-activated to its cytotoxic moiety, fluoroura...more |
| T3D3512 | Hydroxychloroquine | 118-42-3 | Although the exact mechanism of action is unknown, it may be based on ability of hydroxychloroqui...more |
| T3D3514 | Infliximab | 170277-31-3 | Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the solub...more |
| T3D3516 | Itraconazole | 84625-61-6 | Itraconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lano...more |
| T3D3517 | Labetalol | 36894-69-6 | Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastere...more |
| T3D3520 | Melamine | 108-78-1 | Melamine causes carcinomas of the urinary bladder at high doses (in male rats). Formation of blad...more |
| T3D3522 | 1,1-Dimethylbiguanide | 657-24-9 | Metformin's mechanisms of action differ from other classes of oral antihyperglycemic agents. Metf...more |
| T3D3526 | Pentamidine | 100-33-4 | The mode of action of pentamidine is not fully understood. It is thought that the drug interferes...more |
| T3D3529 | Polymyxin B Sulfate | 1405-20-5 | Polymyxin B sulfate has a bactericidal action against almost all gram-negative bacilli except the...more |
| T3D3533 | Sorafenib | 284461-73-0 | Sorafenib interacts with multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kin...more |
| T3D3536 | Telithromycin | 191114-48-4 | Telithromycin acts by binding to domains II and V of 23S rRNA of the 50S ribosomal subunit. By bi...more |
| T3D3537 | Terazosin | 70024-40-7 | Terazosin selectively and competitively inhibits vascular postsynaptic alpha(1)-adrenergic recept...more |
| T3D3539 | Thalidomide | 50-35-1 | In patients with erythema nodosum leprosum (ENL) the mechanism of action is not fully understood....more |
| T3D3542 | Valaciclovir | 124832-26-4 | Valaciclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active me...more |
| T3D3543 | Vancomycin | 1404-90-6 | The bactericidal action of vancomycin results primarily from inhibition of cell-wall biosynthesis...more |
| T3D3544 | Verapamil | 52-53-9 | Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium...more |
| T3D3561 | Guanidine nitrate | 506-93-4 | Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the...more |
| T3D3570 | Methylammonium nitrate | 22113-87-7 | Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the...more |
| T3D3577 | Methyldopa | 555-30-6 | Although the mechanism of action has yet to be conclusively demonstrated, the resultant hypotensi...more |
| T3D3582 | Lysergic Acid Diethylamide | 50-37-3 | LSD preferentially inhibits serotonergic cell firing by acting as an agonist at the 5-HT1A recept...more |
| T3D3583 | Botulinum toxin | 93384-43-1 | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3584 | Botulinum neurotoxin type G | Not Available | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
| T3D3585 | beta-Amanitin | 21150-22-1 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3586 | gamma-Amanitin | 21150-23-2 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3587 | epsilon-Amanitin | 21705-02-2 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3588 | Amanullin | 21803-57-6 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3589 | Amanullinic acid | 54532-45-5 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3590 | Amaninamide | 58311-65-2 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3591 | Amanin | 21150-21-0 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3592 | Proamanullin | 54532-46-6 | The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in ...more |
| T3D3599 | 2-Aminophenol | 95-55-6 | 2-Aminophenol interacts with both adult and fetal hemoglobin, forming methemoglobin. In compariso...more |
| T3D3600 | 4-Aminophenol | 123-30-8 | 4-Aminobiphenyl requires metabolic activation in order to exert its toxicity. This is catalyzed b...more |
| T3D3601 | 3-Aminophenol | 591-27-5 | 3-Aminophenol interacts with both adult and fetal hemoglobin, forming methemoglobin. In compariso...more |
| T3D3602 | Microcystin-LR | 101043-37-2 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3603 | Fumonisin B1 | 116355-83-0 | Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing i...more |
| T3D3604 | Gliotoxin | 67-99-2 | Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certa...more |
| T3D3605 | Ochratoxin A | 303-47-9 | Ochratoxin A has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage...more |
| T3D3606 | Ochratoxin B | 4825-86-9 | Ochratoxin B is thought to inhibit the accumulation of cartilage proteoglycans and general prote...more |
| T3D3607 | Ochratoxin C | 4865-85-4 | Ochratoxin A, a metabolite of Ochratoxin C, has been shown to be weakly mutagenic, possibly by in...more |
| T3D3608 | Microcystin-YR | 101064-48-6 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3609 | Microcystin-RR | 111755-37-4 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3610 | Cyanoginosin-LA | 96180-79-9 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3611 | Microcystin-LF | 154037-70-4 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3613 | Microcystin-LL | 154037-67-9 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3614 | Microcystin-LW | 157622-02-1 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3615 | Microcystin-LY | 123304-10-9 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3616 | Nodularin-R | 118399-22-7 | The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They ...more |
| T3D3621 | Cocoyl sarcosine | 783292-49-9 | While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents m...more |
| T3D3622 | Lauroyl sarcosine | 97-78-9 | While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents m...more |
| T3D3623 | Sodium cocoyl sarcosinate | 61791-59-1 | While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents m...more |
| T3D3624 | Sodium lauroyl sarcosinate | 137-16-6 | While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents m...more |
| T3D3626 | Diazolidinyl urea | 78491-02-8 | Diazolidinyl urea is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when...more |
| T3D3627 | 1,3-Dimethylol-5,5-dimethylhydantoin | 6440-58-0 | DMDM hydantoin is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when in...more |
| T3D3628 | Quaternium-15 | 4080-31-3 | Quaternium-15 is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when int...more |
| T3D3633 | Quaternium-22 | 51812-80-7 | While quaternium-22 itself is not toxic, it is a nitrosating agent. Nitrosating agents may decomp...more |
| T3D3662 | Roquefortine | 58735-64-1 | Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, po...more |
| T3D3667 | Cytochalasin B | 14930-96-2 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3671 | Aflatoxin G2 | 7241-98-7 | Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in tur...more |
| T3D3676 | Cytochalasin A | 14110-64-6 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3677 | Cytochalasin C | 22144-76-9 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3678 | Cytochalasin D | 22144-77-0 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3679 | Cytochalasin E | 36011-19-5 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3680 | Cytochalasin H | 53760-19-3 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3681 | Cytochalasin J | 56144-22-0 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3682 | Dihydrocytochalasin B | 39156-67-7 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3683 | Dihydrocytochalasin B gamma-lactone | 14110-71-5 | Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which th...more |
| T3D3684 | Ergine | 478-94-4 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3685 | Ergonovine | 60-79-7 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3686 | Methylergonovine | 113-42-8 | Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 s...more |
| T3D3687 | Lysergic acid hydroxyethylamide | 3343-15-5 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3688 | Ergocristine | 511-08-0 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3689 | Ergocornine | 564-36-3 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3690 | Ergocryptine | 511-09-1 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3691 | Ergovaline | 2873-38-3 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3692 | Agroclavine | 548-42-5 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3694 | Elymoclavine | 548-43-6 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3695 | Lysergol | 602-85-7 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3696 | Costaclavine | 436-41-9 | Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agon...more |
| T3D3697 | Fumonisin B2 | 116355-84-1 | Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing i...more |
| T3D3736 | Cyclopiazonic acid | 18172-33-3 | Cyclopiazonic acid is potent and specific inhibitor of the endoplasmic and sarcoplasmic reticulum...more |
| T3D3740 | Beauvericin | 26048-05-5 | Beauvericin is cytotoxic and increases ion permeability in cell membranes by forming complexes wi...more |
| T3D3742 | Fumitremorgin A | 12626-18-5 | Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, po...more |
| T3D3743 | Fumitremorgin B | 12626-17-4 | Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, po...more |
| T3D3744 | Fumitremorgin C | 118974-02-0 | Fumitremorgin C inhibits ATP-binding cassette transporter (ACBG2), also known as breast cancer re...more |
| T3D3753 | Butenolide | 16275-44-8 | Butenolide causes lipid peroxidation, disrupting the membrane lipid bilayer and causing damage to...more |
| T3D3754 | Emestrin | 97816-62-1 | Emestrin causes degeneration of the mitochondria in both cardiac muscle cells and hepatocytes, le...more |
| T3D3756 | Enniatin A | 2503-13-1 | Enniatins are toxic due to their ability to act as ionophores, changing ion transport across memb...more |
| T3D3757 | Enniatin A1 | 4530-21-6 | Enniatins are toxic due to their ability to act as ionophores, changing ion transport across memb...more |
| T3D3758 | Enniatin B | 917-13-5 | Enniatins are toxic due to their ability to act as ionophores, changing ion transport across memb...more |
| T3D3759 | Enniatin B1 | 19914-20-6 | Enniatins are toxic due to their ability to act as ionophores, changing ion transport across memb...more |
| T3D3771 | Restrictocin (Aspergillus restrictus) | 1406-72-0 | Restrictocin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single ...more |
| T3D3773 | alpha-Sarcin (Aspergillus giganteus) | 86243-64-3 | alpha-Sarcin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single ...more |
| T3D3775 | Slaframine | 20084-93-9 | Slaframine is a parasympathomimetic compound and causes increased secretion by salivary glands, p...more |
| T3D3776 | Sporidesmin | 1456-55-9 | Sporidesmin and its reduced (dithiol) form undergo cyclic reduction/autoxidation reactions with g...more |
| T3D3782 | Verruculogen | 12771-72-1 | Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, po...more |
| T3D3787 | 6-Deisopropylatrazine | 1007-28-9 | Not Available |
| T3D3791 | Ametryn | 834-12-8 | Not Available |
| T3D3792 | Amitraz | 33089-61-1 | The pharmacological activity of amitraz includes different mechanisms of action leading to toxic ...more |
| T3D3793 | Anilazine | 101-05-3 | Anilazine was found to be mutagenic. |
| T3D3796 | Benfluralin | 1861-40-1 | Not Available |
| T3D3800 | Boscalid | 188425-85-6 | Not Available |
| T3D3802 | Buprofezin | 69327-76-0 | Not Available |
| T3D3806 | Chloridazon | 1698-60-8 | Not Available |
| T3D3809 | Chlorsulfuron | 64902-72-3 | Not Available |
| T3D3815 | Clothianidin | 210880-92-5 | Not Available |
| T3D3816 | Cyanamide | 420-04-2 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D3817 | Cyanazine | 21725-46-2 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D3819 | Cymoxanil | 57966-95-7 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D3820 | Cyprodinil | 121552-61-2 | Not Available |
| T3D3822 | Dazomet | 533-74-4 | Not Available |
| T3D3823 | Dichloran | 99-30-9 | Not Available |
| T3D3826 | Dicrotophos | 141-66-2 | Dicrotophos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibi...more |
| T3D3827 | Diethyltoluamide | 134-62-3 | Not Available |
| T3D3828 | Difenoconazole | 119446-68-3 | Not Available |
| T3D3830 | Dimethenamid | 87674-68-8 | Not Available |
| T3D3832 | Ethalfluralin | 55283-68-6 | Not Available |
| T3D3836 | Fenamidone | 161326-34-7 | Not Available |
| T3D3838 | Fenhexamid | 126833-17-8 | Not Available |
| T3D3842 | Fluazinam | 79622-59-6 | Not Available |
| T3D3843 | Flufenacet | 142459-58-3 | Not Available |
| T3D3846 | Flumiclorac-pentyl | 87546-18-7 | Not Available |
| T3D3847 | Flumioxazin | 103361-09-7 | Not Available |
| T3D3848 | Fluroxypyr | 69377-81-7 | Not Available |
| T3D3849 | Fluroxypyr-meptyl | 81406-37-3 | Not Available |
| T3D3852 | Flutolanil | 66332-96-5 | Not Available |
| T3D3853 | Folpet | 133-07-3 | Not Available |
| T3D3854 | Foramsulfuron | 173159-57-4 | Not Available |
| T3D3856 | Halosulfuron-methyl | 100784-20-1 | Not Available |
| T3D3857 | Hexazinone | 51235-04-2 | Not Available |
| T3D3859 | Icaridin | 119515-38-7 | Not Available |
| T3D3860 | Enilconazole | 35554-44-0 | Not Available |
| T3D3861 | Imazamox | 114311-32-9 | Not Available |
| T3D3862 | Imazapic | 104098-48-8 | Not Available |
| T3D3863 | Imazaquin | 81335-37-7 | Not Available |
| T3D3864 | Indoxacarb | 173584-44-6 | It is thought that indoxacarb's aromatic metabolites biotransform to active intermediates that pr...more |
| T3D3865 | Iodosulfuron-methyl-sodium | 144550-36-7 | Not Available |
| T3D3866 | Iprodione | 36734-19-7 | Not Available |
| T3D3867 | Isoxaben | 82558-50-7 | Not Available |
| T3D3875 | Mesosulfuron-methyl | 208465-21-8 | Not Available |
| T3D3877 | Metam-sodium hydrate | 6734-80-1 | Not Available |
| T3D3880 | Methoxyfenozide | 161050-58-4 | Not Available |
| T3D3883 | Metsulfuron-methyl | 74223-64-6 | Not Available |
| T3D3885 | MGK | 113-48-4 | Not Available |
| T3D3888 | (E)-Monocrotophos | 6923-22-4 | (E)-Monocrotophos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase ...more |
| T3D3889 | Myclobutanil | 88671-89-0 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D3890 | Napropamide | 15299-99-7 | Not Available |
| T3D3891 | Niclosamide | 50-65-7 | Niclosamide works by killing tapeworms on contact. Adult worms (but not ova) are rapidly killed, ...more |
| T3D3893 | Norflurazon | 27314-13-2 | Not Available |
| T3D3895 | Oxasulfuron | 144651-06-9 | Not Available |
| T3D3897 | Paclobutrazol | 76738-62-0 | Not Available |
| T3D3902 | Primisulfuron-methyl | 86209-51-0 | Not Available |
| T3D3903 | Prochloraz | 67747-09-5 | Prochloraz acts in vitro as a an aromatase inhibitor, aryl hydrocarbon receptor agonist, androgen...more |
| T3D3905 | Prometon | 1610-18-0 | Not Available |
| T3D3906 | Prometryn | 7287-19-6 | Not Available |
| T3D3908 | Propazine | 139-40-2 | Not Available |
| T3D3910 | Propiconazole | 60207-90-1 | Propiconazole can decrease cholesterol levels that may cause polyploidy and disruption of mitotic...more |
| T3D3912 | Prosulfuron | 94125-34-5 | Not Available |
| T3D3922 | Simazine | 122-34-9 | Not Available |
| T3D3923 | Spiroxamine | 118134-30-8 | Not Available |
| T3D3925 | Tebufenozide | 112410-23-8 | Not Available |
| T3D3926 | Tebufenpyrad | 119168-77-3 | Not Available |
| T3D3928 | Tebuthiuron | 34014-18-1 | Not Available |
| T3D3930 | Tetraconazole | 112281-77-3 | Not Available |
| T3D3932 | Thiamethoxam | 153719-23-4 | Not Available |
| T3D3934 | Thiophanate-methyl | 23564-05-8 | Not Available |
| T3D3936 | Triasulfuron | 82097-50-5 | Not Available |
| T3D3937 | Tribenuron-methyl | 101200-48-0 | Not Available |
| T3D3940 | Trifloxysulfuron-sodium | 199119-58-9 | Not Available |
| T3D3941 | Triflusulfuron-methyl | 126535-15-7 | Not Available |
| T3D3942 | Vinclozolin | 50471-44-8 | Vinclozolin and some of its metabolites have antiandrogenic activity. Vinclozolin's main toxic ef...more |
| T3D3956 | Cotinine | 486-56-6 | Not Available |
| T3D4015 | Protopine | 130-86-9 | Protopine has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as ...more |
| T3D4016 | Vincristine | 57-22-7 | The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at ...more |
| T3D4017 | Vinblastine | 865-21-4 | The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at ...more |
| T3D4019 | Paclitaxel | 33069-62-4 | Paclitaxel interferes with the normal function of microtubule growth. Whereas drugs like colchici...more |
| T3D4023 | Neosaxitoxin | 64296-20-4 | Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated ...more |
| T3D4024 | L-Hypoglycin A | 156-56-9 | Generally, hypoglycin is an amino acid and chemically related to lysine. It competitively binds t...more |
| T3D4025 | Hypoglycin B | 502-37-4 | Generally, hypoglycin is an amino acid and chemically related to lysine. It competitively binds t...more |
| T3D4026 | (+)-Calycanthine | 595-05-1 | The principal alkaloid of the family Calycanthaceae, calycanthine has long been recognized as a c...more |
| T3D4027 | (S)-Isocorydine | 475-67-2 | Isocorydine induces G2/M phase arrest by increasing cyclin B1 and p-CDK1 expression levels, which...more |
| T3D4028 | (S)-2-Propylpiperidine | 458-88-8 | (S)-2-Propylpiperidine is a neurotoxin which disrupts the peripheral nervous system. It is toxic ...more |
| T3D4031 | Phomopsin A | 64925-80-0 | Not Available |
| T3D4032 | Cyclochlorotine | 12663-46-6 | Cyclochlorotine (CC) causes hepatic necrosis and has carcinogenic properties. The in vitro applic...more |
| T3D4038 | Gonyautoxin I | 60748-39-2 | The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-...more |
| T3D4039 | Gonyautoxin II | 60508-89-6 | The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-...more |
| T3D4040 | Domoic acid | 14277-97-5 | Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropi...more |
| T3D4042 | alpha-Solanine | 20562-02-1 | Solanum glycoalkaloids can inhibit cholinesterase, disrupt cell membranes, and be teratogenic (ca...more |
| T3D4048 | Decarbamoylsaxitoxin | 58911-04-9 | Not Available |
| T3D4050 | alpha-Chaconine | 20562-03-2 | Alpha-Chaconine has inhibitory effect on lung adenocarcinoma cell metastasis in vitro. Alpha-chac...more |
| T3D4055 | Vindoline | Not Available | Not Available |
| T3D4057 | Stizolobate | 15911-87-2 | Not Available |
| T3D4058 | Stizolobinate | Not Available | Not Available |
| T3D4059 | Senecionine | 130-01-8 | Senecionine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids a...more |
| T3D4060 | Retronecine | 480-85-3 | Retronecine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids a...more |
| T3D4061 | Veratridine | 71-62-5 | Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a...more |
| T3D4062 | Tentoxin | 28540-82-1 | Not Available |
| T3D4064 | Lycorine | 476-28-8 | Lycorine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor...more |
| T3D4065 | Mesaconitine | 2752-64-9 | Mesaconitine (MA) is one of the Aconitum sp. alkaloids. The primary toxicity of Aconitum sp. alka...more |
| T3D4068 | C-Curarine | 7168-64-1 | It has been prpoposed that surarine speeds up destruction of chemical transmitter, and raises the...more |
| T3D4070 | Gelsemicine | 6887-28-1 | Not Available |
| T3D4071 | Gelsemine | 509-15-9 | Gelsemine has convulsant effects with a similar mechanism of action to strychnine. Strychnine is ...more |
| T3D4073 | Bicuculline | 485-49-4 | The action of bicuculline is primarily on the ionotropic GABAA receptors, which are ligand-gated ...more |
| T3D4075 | Methylconiine | 35305-13-6 | Not Available |
| T3D4076 | Pseudoconhydrine | 140-55-6 | Not Available |
| T3D4077 | Echimidine | 520-68-3 | Not Available |
| T3D4078 | Lasiocarpine | 303-34-4 | Lasiocarpine is toxic to liver cells but not to lung cells, which is unable to metabolize the pyr...more |
| T3D4079 | Senkirkine | 2318-18-5 | Not Available |
| T3D4081 | Matrine | 519-02-8 | The nervous system is the main target organ by the toxicity of matrine. Morphological observation...more |
| T3D4082 | Cyclopamine | 4449-51-8 | Cyclopamine causes usually fatal birth defects. It can prevent the fetal brain from dividing into...more |
| T3D4083 | Jervine | 469-59-0 | Jervine's biological activity is mediated via its interaction with the 7 pass trans membrane prot...more |
| T3D4084 | Veratramine | 60-70-8 | Veratramine produces a characteristic excitatory action on the central nervous system, producing ...more |
| T3D4085 | Tazettine | 507-79-9 | Not Available |
| T3D4087 | Chelidonine | 476-32-4 | Chelidonine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibi...more |
| T3D4088 | Lyngbyatoxin A | 70497-14-2 | Lyngbyatoxin A is a tumor promoter. Lyngbyatoxin A and related compounds bind to the cysteine-ric...more |
| T3D4089 | Enniatin D | Not Available | Not Available |
| T3D4090 | Neosurugatoxin | 80680-43-9 | Not Available |
| T3D4092 | Dicentrine | 517-66-8 | Dicentrine was found to be a potent alpha 1-adrenoceptor blocking agent in rat thoracic aorta as ...more |
| T3D4094 | Valinopine | Not Available | Not Available |
| T3D4098 | Domesticine | 476-71-1 | Not Available |
| T3D4100 | Gelsedine | 7096-96-0 | Not Available |
| T3D4101 | Conhydrine | 495-20-5 | Not Available |
| T3D4103 | Nantenine | 2565-01-7 | Nantenine is an antagonist at both the α1 adrenergic receptor and the 5-HT2A serotonin receptor, ...more |
| T3D4105 | Aconine | 509-20-6 | Not Available |
| T3D4121 | Protoveratrine A | 143-57-7 | Not Available |
| T3D4122 | Protoveratrine B | 124-97-0 | Not Available |
| T3D4124 | Anatoxin a | 64285-06-9 | Anatoxin-a is an agonist of both neuronal α4β2 and α4 nicotinic acetylcholine receptors present i...more |
| T3D4126 | Sporidesmin J | 69799-25-3 | Not Available |
| T3D4132 | Acromelic acid A | 86630-09-3 | Not Available |
| T3D4134 | Taxine B | 1361-51-9 | Not Available |
| T3D4138 | Anatoxin-a(s) | 103170-78-1 | Anatoxin-a(s) is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhi...more |
| T3D4142 | Gonyautoxin 5 | 64296-25-9 | Not Available |
| T3D4143 | Gonyautoxin 6 | 82810-44-4 | Not Available |
| T3D4144 | Gonyautoxin 8 | 80226-62-6 | Not Available |
| T3D4145 | Decarbamoylgonyautoxin 1 | 122075-86-9 | Not Available |
| T3D4146 | 11-Deoxytetrodotoxin | 113564-23-1 | Not Available |
| T3D4147 | Isodomoic acid A | 101899-44-9 | Not Available |
| T3D4149 | Guanidoacetic acid | 352-97-6 | Uremic toxins such as guanidinoacetic acid are actively transported into the kidneys via organic ...more |
| T3D4154 | Norepinephrine | 51-41-2 | Uremic toxins such as noradrenalin are actively transported into the kidneys via organic ion tran...more |
| T3D4156 | L-Cysteine | 52-90-4 | Uremic toxins such as cysteine are actively transported into the kidneys via organic ion transpor...more |
| T3D4159 | Hippuric acid | 495-69-2 | Uremic toxins such as hippuric acid are actively transported into the kidneys via organic ion tra...more |
| T3D4161 | Homocysteine | 454-29-5 | Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, whi...more |
| T3D4165 | 2-Aminobenzoic acid | 118-92-3 | Uremic toxins such as anthranilic acid are actively transported into the kidneys via organic ion ...more |
| T3D4166 | Spermine | 71-44-3 | Uremic toxins such as spermine are actively transported into the kidneys via organic ion transpor...more |
| T3D4167 | Spermidine | 124-20-9 | Uremic toxins such as spermidine are actively transported into the kidneys via organic ion transp...more |
| T3D4168 | Niacinamide | 98-92-0 | Uremic toxins such as nicotinamide are actively transported into the kidneys via organic ion tran...more |
| T3D4170 | Methylguanidine | 471-29-4 | Uremic toxins such as methylguanidine are actively transported into the kidneys via organic ion t...more |
| T3D4171 | Asymmetric dimethylarginine | 30315-93-6 | Uremic toxins such as asymmetric dimethylarginine are actively transported into the kidneys via o...more |
| T3D4172 | Guanidine | 113-00-8 | Uremic toxins such as guaniidine are actively transported into the kidneys via organic ion transp...more |
| T3D4173 | Argininic acid | 157-07-3 | Uremic toxins such as arginic acid are actively transported into the kidneys via organic ion tran...more |
| T3D4174 | Guanidinosuccinic acid | 6133-30-8 | Uremic toxins such as guanidinosuccinic acid are actively transported into the kidneys via organi...more |
| T3D4175 | 8-Hydroxy-deoxyguanosine | 88847-89-6 | Uremic toxins such as 8-Hydroxy-2Х-deoxyguanosine are actively transported into the kidneys via o...more |
| T3D4176 | Symmetric dimethylarginine | 30344-00-4 | Uremic toxins such as symmetric dimethylarginine are actively transported into the kidneys via or...more |
| T3D4177 | Pentosidine | 124505-87-9 | Uremic toxins such as pentosidine are actively transported into the kidneys via organic ion trans...more |
| T3D4196 | Alpha-keto-delta-guanidinovaleric acid | 3715-10-4 | Uremic toxins such as alpha-keto-delta-guanidinoacetic acid are actively transported into the kid...more |
| T3D4198 | N(6)-Carboxymethyllysine | 5746-04-3 | Uremic toxins such as carboxymethyllysine are actively transported into the kidneys via organic i...more |
| T3D4199 | Dihydroxyphenylalanine | 63-84-3 | Uremic toxins such as dihydroxyphenylalanine are actively transported into the kidneys via organi...more |
| T3D4202 | Carbamic acid | 463-77-4 | Carbamic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhi...more |
| T3D4204 | Mechlorethamine | 51-75-2 | Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases,...more |
| T3D4213 | 2-Aminonaphthalene | 91-59-8 | Not Available |
| T3D4215 | N'-nitrosonornicotine | 16543-55-8 | Not Available |
| T3D4217 | O-Toluidine | 95-53-4 | Not Available |
| T3D4218 | 2,6-Dimethylaniline | 87-62-7 | Treatment of AS52 cells with N-OH-2,6-dimethylaniline (2,6-DMA) and 2,6-DMAP led to intracellular...more |
| T3D4219 | p-Chloroaniline | 106-47-8 | Not Available |
| T3D4232 | Cylindrospermopsin | 143545-90-8 | Not Available |
| T3D4233 | Lyngbyatoxin-a | Not Available | Not Available |
| T3D4234 | Lipopolysaccharide | Not Available | Not Available |
| T3D4248 | L-Lysine | 56-87-1 | Proteins of the herpes simplex virus are rich in L-arginine, and tissue culture studies indicate ...more |
| T3D4250 | Gamma-Aminobutyric acid | 56-12-2 | Not Available |
| T3D4252 | 2-Methylacetoacetyl-CoA | 6712-01-2 | Not Available |
| T3D4259 | Aminoadipic acid | 542-32-5 | Not Available |
| T3D4260 | Succinyl-CoA | 604-98-8 | Not Available |
| T3D4267 | 3-Hydroxy-3-methylglutaryl-CoA | 1553-55-5 | Not Available |
| T3D4271 | Gamma-Glutamylcysteine | 636-58-8 | Not Available |
| T3D4272 | 5-Aminoimidazole-4-carboxamide | 360-97-4 | Not Available |
| T3D4273 | 5-Aminolevulinic acid | 106-60-5 | According to the presumed mechanism of action, photosensitization following application of aminol...more |
| T3D4274 | Porphobilinogen | 487-90-1 | Not Available |
| T3D4275 | Adenosine | 58-61-7 | Adenosine slows conduction time through the AV node and can interrupt the reentry pathways throug...more |
| T3D4276 | Adenosine triphosphate | 56-65-5 | ATP is able to store and transport chemical energy within cells. ATP also plays an important role...more |
| T3D4277 | ADP | 58-64-0 | Not Available |
| T3D4278 | Deoxyadenosine triphosphate | 1927-31-7 | Not Available |
| T3D4279 | Adenine | 73-24-5 | Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached ...more |
| T3D4280 | Succinyladenosine | 4542-23-8 | Not Available |
| T3D4281 | SAICAR | 3031-95-6 | Not Available |
| T3D4289 | L-Arginine | 74-79-3 | Many of supplemental L-arginine's activities, including its possible anti-atherogenic actions, ma...more |
| T3D4290 | Creatine | 57-00-1 | In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate....more |
| T3D4291 | Homo-L-arginine | 156-86-5 | Not Available |
| T3D4294 | Argininosuccinic acid | 2387-71-5 | Not Available |
| T3D4295 | Citrulline | 372-75-8 | L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn resp...more |
| T3D4296 | L-Glutamic acid | 56-86-0 | Glutamate activates both ionotropic and metabotropic glutamate receptors. The ionotropic ones bei...more |
| T3D4297 | 3-Methoxytyrosine | 7636-26-2 | Methoxytyrosine is one of the main biochemical markers for aromatic L-amino acid decarboxylase de...more |
| T3D4298 | 5-Hydroxy-L-tryptophan | 4350-09-8 | 5-Hydroxy-L-tryptophan is the immediate precursor of the neurotransmitter serotonin. An accumulat...more |
| T3D4299 | 3-Methoxytyramine | 554-52-9 | Not Available |
| T3D4300 | Dopamine | 51-61-6 | Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter ...more |
| T3D4301 | Ureidoisobutyric acid | 2905-86-4 | Not Available |
| T3D4312 | Carnosine | 305-84-0 | Not Available |
| T3D4313 | Anserine | 584-85-0 | Not Available |
| T3D4318 | Glycine | 56-40-6 | In the CNS, there exist strychnine-sensitive glycine binding sites as well as strychnine-insensit...more |
| T3D4319 | L-Glutamine | 56-85-9 | Supplemental L-glutamine's possible immunomodulatory role may be accounted for in a number of way...more |
| T3D4320 | L-Alanine | 56-41-7 | L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. I...more |
| T3D4326 | L-Cystathionine | 56-88-2 | Not Available |
| T3D4327 | L-Homocystine | 626-72-2 | Not Available |
| T3D4328 | L-Methionine | 63-68-3 | The mechanism of the possible anti-hepatotoxic activity of L-methionine is not entirely clear. It...more |
| T3D4329 | Ornithine | 70-26-8 | L-Ornithine is metabolised to L-arginine. L-arginine stimulates the pituitary release of growth h...more |
| T3D4336 | Dimethylglycine | 1118-68-9 | Not Available |
| T3D4346 | Beta-Alanine | 107-95-9 | Not Available |
| T3D4347 | Homocarnosine | 3650-73-5 | Not Available |
| T3D4352 | Glutathione | 70-18-8 | Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathi...more |
| T3D4355 | Psychosine sulfate | Not Available | Not Available |
| T3D4362 | L-Asparagine | 70-47-3 | Asparagine, a non-essential amino acid is important in the metabolism of toxic ammonia in the bod...more |
| T3D4363 | L-Histidine | 71-00-1 | Since the actions of supplemental L-histidine are unclear, any postulated mechanism is entirely s...more |
| T3D4364 | L-Isoleucine | 73-32-5 | (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as...more |
| T3D4365 | L-Leucine | 61-90-5 | This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Beca...more |
| T3D4366 | L-Phenylalanine | 63-91-2 | Extremely high serum levels of phenylalanine are found in patients with the inborn error of metab...more |
| T3D4367 | L-Serine | 56-45-1 | L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of ...more |
| T3D4368 | L-Threonine | 72-19-5 | L-Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in cont...more |
| T3D4369 | L-Tryptophan | 73-22-3 | A number of important side reactions occur during the catabolism of tryptophan on the pathway to ...more |
| T3D4370 | L-Valine | 72-18-4 | (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as...more |
| T3D4371 | L-Tyrosine | 60-18-4 | Tyrosine is produced in cells by hydroxylating the essential amino acid phenylalanine. This relat...more |
| T3D4372 | Hawkinsin | 63224-90-8 | Not Available |
| T3D4377 | Histamine | 51-45-6 | Not Available |
| T3D4380 | 1-Methylhistamine | 501-75-7 | Not Available |
| T3D4385 | Taxine A | 1361-49-5 | Not Available |
| T3D4394 | Ostreocin D | Not Available | Not Available |
| T3D4395 | beta-Ergocryptine | 20315-46-2 | Not Available |
| T3D4396 | 2-Methyl-3-hydroxybutyryl-CoA | 52227-66-4 | Not Available |
| T3D4398 | Saccharopine | 997-68-2 | Not Available |
| T3D4399 | Homocitrulline | 1190-49-4 | Not Available |
| T3D4400 | Sepiapterin | 17094-01-8 | Not Available |
| T3D4401 | Ureidopropionic acid | 462-88-4 | Not Available |
| T3D4403 | 3-Mercaptolactate-cysteine disulfide | 18841-42-4 | Not Available |
| T3D4406 | O-Phosphoethanolamine | 1071-23-4 | Not Available |
| T3D4410 | D-Proline | 344-25-2 | Not Available |
| T3D4411 | L-Proline | 147-85-3 | Glycogenic, by L-Proline oxidase in the kidney, it is ring-opened and is oxidized to form L-Gluta...more |
| T3D4412 | 4-Hydroxy-L-proline | 30724-02-8 | Not Available |
| T3D4413 | 4-Hydroxyproline | 51-35-4 | Not Available |
| T3D4414 | Isovaleryl-CoA | 6244-91-3 | Not Available |
| T3D4415 | N-acetyltryptophan | 1218-34-4 | Not Available |
| T3D4416 | Creatinine | 60-27-5 | Not Available |
| T3D4418 | D-Glutamine | 5959-95-5 | Not Available |
| T3D4419 | D-Lysine | 923-27-3 | Not Available |
| T3D4420 | Malonyl-CoA | 524-14-1 | Not Available |
| T3D4421 | 3-Aminoisobutanoic acid | 144-90-1 | Not Available |
| T3D4429 | R-Methylmalonyl-CoA | 73173-92-9 | Not Available |
| T3D4430 | Deoxyuridine triphosphate | 1173-82-6 | Deoxyuridine triphosphate (dUTP) can be misincorporated into DNA and cause DNA damage. The extent...more |
| T3D4431 | Deoxyuridine | 951-78-0 | Not Available |
| T3D4432 | Thymidine | 50-89-5 | Not Available |
| T3D4433 | Taurine | 107-35-7 | Not Available |
| T3D4434 | S-Sulfocysteine | 1637-71-4 | S-Sulfocysteine (SSC) is a very potent NMDA-receptor agonist. Electrophysiological studies have s...more |
| T3D4435 | Tyramine | 51-67-2 | Tyramine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor...more |
| T3D4446 | Glycylglycylglycine | 556-33-2 | Not Available |
| T3D4447 | Propionyl-CoA | 317-66-8 | In propionic aciduria, propionyl CoA accumulates within the mitochondria in massive quantities; f...more |
| T3D4448 | dGTP | 2564-35-4 | Not Available |
| T3D4449 | Guanosine | 118-00-3 | Not Available |
| T3D4450 | Inosine | 58-63-9 | Inosine has been found to have potent axon-promoting effects in vivo following unilateral transec...more |
| T3D4451 | Deoxyinosine | 890-38-0 | Not Available |
| T3D4452 | Allysine | 1962-83-0 | Not Available |
| T3D4455 | S-Adenosylhomocysteine | 979-92-0 | Not Available |
| T3D4456 | S-Adenosylmethionine | 29908-03-0 | S-Adenosylmethionine (SAMe) is a natural substance present in the cells of the body. It is a dire...more |
| T3D4458 | Sarcosine | 107-97-1 | Sarcosine is an oncometabolite. Sarcosine appears to upregulate the expression of the potent onco...more |
| T3D4463 | Hexanoyl-CoA | 5060-32-2 | Not Available |
| T3D4468 | Chitobiose | 577-76-4 | Not Available |
| T3D4476 | Acetamiprid | 135410-20-7 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D4477 | Atrazine | 1912-24-9 | Not Available |
| T3D4478 | Bensulfuron-methyl | 83055-99-6 | Not Available |
| T3D4480 | Butralin | 33629-47-9 | Not Available |
| T3D4483 | Carboxin | 5234-68-4 | Not Available |
| T3D4487 | Clomazone | 81777-89-1 | Clomazone induces oxidative stress and AChE inhibition in human erythrocytes (in vitro), suggesti...more |
| T3D4491 | Cyclanilide | 113136-77-9 | Not Available |
| T3D4492 | Cyproconazole | 94361-06-5 | Not Available |
| T3D4493 | Cyromazine | 66215-27-8 | Not Available |
| T3D4495 | Dimethomorph | 110488-70-5 | Not Available |
| T3D4497 | Diphenylamine | 122-39-4 | Diphenylamine uncouples mitochondrial oxidative phosphorylation, resulting in a decrease in hepat...more |
| T3D4500 | Diuron | 330-54-1 | Diuron has been reported to bind to androgen receptors. This suggests that diuron may block the r...more |
| T3D4503 | Ethylenethiourea | 96-45-7 | Not Available |
| T3D4504 | Famoxadone | 131807-57-3 | Not Available |
| T3D4506 | Fenbuconazole | 114369-43-6 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D4510 | Flumetralin | 62924-70-3 | Not Available |
| T3D4511 | Fluometuron | 2164-17-2 | Not Available |
| T3D4513 | Forchlorfenuron | 68157-60-8 | Not Available |
| T3D4514 | Hexaconazole | 79983-71-4 | Not Available |
| T3D4515 | Hexythiazox | 78587-05-0 | Not Available |
| T3D4516 | Imazapyr | 81334-34-1 | Not Available |
| T3D4522 | Oryzalin | 19044-88-3 | Not Available |
| T3D4523 | Picloram | 1918-02-1 | Not Available |
| T3D4527 | Prodiamine | 29091-21-2 | Not Available |
| T3D4532 | Pyrimethanil | 53112-28-0 | Not Available |
| T3D4540 | Thiacloprid | 111988-49-9 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D4541 | Thidiazuron | 51707-55-2 | The US EPA has found no information indicating thidiazuron shares a common mechanism of toxicity ...more |
| T3D4542 | Thiram | 137-26-8 | Not Available |
| T3D4548 | Trifluralin | 1582-09-8 | Not Available |
| T3D4551 | Doxylamine | 469-21-6 | Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors....more |
| T3D4552 | Eszopiclone | 138729-47-2 | The mechanism of action of Eszopiclone is not completely understood. It is thought that Eszopiclo...more |
| T3D4553 | Carbinoxamine | 486-16-8 | Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the...more |
| T3D4554 | Brompheniramine | 86-22-6 | Brompheniramine works by acting as an antagonist of the H1 histamine receptors. It also functions...more |
| T3D4555 | Pseudoephedrine | 90-82-4 | Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. ...more |
| T3D4556 | Guaifenesin | 93-14-1 | Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathet...more |
| T3D4557 | Desloratadine | 100643-71-8 | Like other H1-blockers, Desloratadine competes with free histamine for binding at H1-receptors in...more |
| T3D4558 | Azelastine | 58581-89-8 | Azelastine competes with histamine for the H1-receptor sites on effector cells and acts as an ant...more |
| T3D4560 | Promethazine | 60-87-7 | Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor s...more |
| T3D4561 | Amobarbital | 57-43-2 | Amobarbital (like all barbiturates) works by binding to the GABAA receptor at either the alpha or...more |
| T3D4562 | Heroin | 561-27-3 | Heroin is a mu-opioid agonist. It acts on endogenous mu-opioid receptors that are spread in discr...more |
| T3D4563 | Dexmethylphenidate | 40431-64-9 | Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transpo...more |
| T3D4564 | Clobazam | 22316-47-8 | Clobazam binds at distinct binding sites associated with the chloride ionopore at the post-synapt...more |
| T3D4565 | Haloxazolam | 59128-97-1 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4566 | Camazepam | 36104-80-0 | Camazepam has been shown to bind competitively to benzodiazepine receptors in the brain with a re...more |
| T3D4567 | Delorazepam | 2894-67-9 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4568 | Ethyl loflazepate | 29177-84-2 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4569 | Cloxazolam | 24166-13-0 | Cloxazolam is a long acting benzodiazepine. It acts as a prodrug, with pharmacologically active m...more |
| T3D4570 | Fludiazepam | 3900-31-0 | Fludiazepam has similar action to diazepam, but binds with four times more affinity to benzodiaze...more |
| T3D4571 | Ketazolam | 27223-35-4 | Benzodiazepines share a similar chemical structure and their effects in humans are mainly produce...more |
| T3D4572 | Tofisopam | 22345-47-7 | Tofisopam does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid recepto...more |
| T3D4582 | 1,N2-propanodeoxyguanosine | Not Available | Not Available |
| T3D4583 | Ethyl carbamate | 51-79-6 | Ethyl carbamate is genotoxic and a potent carcinogen. It exerts its effects through the formatio...more |
| T3D4585 | Lormetazepam | 848-75-9 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4586 | Pinazepam | 52463-83-9 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4587 | Tetrazepam | 10379-14-3 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4620 | Urea | 57-13-6 | Not Available |
| T3D4623 | 2-Amino-1-methyl-6-phenyl-1H-imidazo [4,5-b]pyridine | Not Available | Not Available |
| T3D4626 | 4-(N-Nitrosomethylamino)-1-(3-pyridinyl)-1-butanone | Not Available | Not Available |
| T3D4630 | 3-Aminobiphenyl | 2243-47-2 | Not Available |
| T3D4631 | N-(2-Cyanoethyl)valine | 51078-49-0 | Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more |
| T3D4638 | S-(2-Hydroxy-1-phenylethyl) cysteine | Not Available | Not Available |
| T3D4645 | Acrivastine | 87848-99-5 | Not Available |
| T3D4646 | Doxefazepam | 40762-15-0 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4647 | Loprazolam | 61197-73-7 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4648 | Medazepam | 2898-12-6 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4649 | Mexazolam | 31868-18-5 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4650 | Nimetazepam | 2011-67-8 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4651 | Oxazolam | 24143-17-7 | Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and ...more |
| T3D4667 | N2-Succinoylarginine | 2478-02-6 | Not Available |
| T3D4669 | 2,4-Toluenediamine | 95-80-7 | Not Available |
| T3D4671 | 2-Amino-3-methylimidazo[4,5-f]quinoline | 76180-96-6 | Not Available |
| T3D4672 | 4,4'-Methylenedianiline | 101-77-9 | After 4,4'-Methylenedianiline enters to our body, it is transported in the blood or stored in tis...more |
| T3D4675 | Arecoline | 63-75-2 | Arecoline is the primary active ingredient responsible for the central nervous system effects of ...more |
| T3D4676 | Azacitidine | 320-67-2 | Azacitidine (5-azacytidine) is a chemical analogue of the cytosine nucleoside used in DNA and RNA...more |
| T3D4679 | C.I. Acid Violet 49 | 1694-09-3 | Not Available |
| T3D4681 | Carmustine | 154-93-8 | Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA pro...more |
| T3D4684 | Chlorambucil | 305-03-3 | Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases,...more |
| T3D4689 | Dacarbazine | 4342-03-4 | The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an...more |
| T3D4700 | Lomustine | 13010-47-4 | Lomustine is a highly lipophilic nitrosourea compound which undergoes hydrolysis in vivo to form ...more |
| T3D4702 | Melphalan | 148-82-3 | Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases ...more |
| T3D4703 | Metronidazole | 443-48-1 | Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to th...more |
| T3D4704 | Monocrotaline | 315-22-0 | Not Available |
| T3D4705 | Nitrilotriacetic Acid | 139-13-9 | Not Available |
| T3D4707 | Phenacetin | 62-44-2 | Phenacetin's analgesic effects are due to its actions on the sensory tracts of the spinal cord. I...more |
| T3D4711 | Procarbazine | 671-16-9 | The precise mode of cytotoxic action of procarbazine has not been clearly defined. There is evide...more |
| T3D4714 | Tamoxifen | 10540-29-1 | Tamoxifen is a nonsteroidal agent that binds to estrogen receptors (ER), inducing a conformationa...more |
| T3D4718 | Uracil mustard | 66-75-1 | After activation, it binds preferentially to the guanine and cytosine moieties of DNA, leading to...more |
| T3D4719 | Zalcitabine | 7481-89-2 | Zalcitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Im...more |
| T3D4726 | Alteplase | 105857-23-6 | Alteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 dom...more |
| T3D4727 | Streptokinase | 9002-01-1 | Plasminogen is an inactive molecule that becomes activated to plasmin when the Arg/Val bond is cl...more |
| T3D4729 | Diclofenac | 15307-86-5 | The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte...more |
| T3D4732 | Tacrolimus | 104987-11-3 | The mechanism of action of tacrolimus in atopic dermatitis is not known. While the following have...more |
| T3D4733 | Quinapril | 85441-61-8 | There are two isoforms of ACE: the somatic isoform, which exists as a glycoprotein comprised of a...more |
| T3D4734 | Salmeterol | 89365-50-4 | Salmeterol's long, lipophilic side chain binds to exosites near beta(2)-receptors in the lungs an...more |
| T3D4735 | Salbutamol | 18559-94-9 | Salbutamol is a beta(2)-adrenergic agonist and thus it stimulates beta(2)-adrenergic receptors. B...more |
| T3D4736 | Fludarabine | 75607-67-9 | Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intra...more |
| T3D4737 | Amiodarone | 1951-25-3 | The antiarrhythmic effect of amiodarone may be due to at least two major actions. It prolongs the...more |
| T3D4738 | Encainide | 66778-36-7 | Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes th...more |
| T3D4739 | Imipenem | 74431-23-5 | Imipenem acts as an antimicrobial through the inhibition of cell wall synthesis of various gram-p...more |
| T3D4741 | Aminopterin | 54-62-6 | Aminopterin is an amino derivative of folic acid which binds competitively to the dihydrofolate r...more |
| T3D4752 | Nitrofural | 59-87-0 | The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, espec...more |
| T3D4759 | Liothyronine | 6893-02-3 | The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an ...more |
| T3D4764 | Erythromycin | 114-07-8 | Erythromycin acts by penetrating the bacterial cell membrane and reversibly binding to the 50 S s...more |
| T3D4767 | Hydroxyurea | 127-07-1 | Hydroxyurea is converted to a free radical nitroxide (NO) in vivo, and transported by diffusion i...more |
| T3D4768 | Flutamide | 13311-84-7 | Flutamide is a nonsteroidal antiandrogen that blocks the action of both endogenous and exogenous ...more |
| T3D4769 | Ethanolamine | 141-43-5 | Not Available |
| T3D4774 | Cladribine | 4291-63-8 | Cladribine is structurally related to fludarabine and pentostatin but has a different mechanism o...more |
| T3D4777 | Isoniazid | 54-85-3 | Isoniazid is a prodrug and must be activated by bacterial catalase. Specficially, activation is a...more |
| T3D4779 | Pyrimethamine | 58-14-0 | Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthes...more |
| T3D4781 | Hydrochlorothiazide | 58-93-5 | Hydrochlorothiazide, a thiazide diuretic, inhibits water reabsorption in the nephron by inhibitin...more |
| T3D4783 | Nilutamide | 63612-50-0 | Nilutamide competes with androgen for the binding of androgen receptors, consequently blocking th...more |
| T3D4789 | Troglitazone | 97322-87-7 | Troglitazone is a thiazolidinedione antidiabetic agent that lowers blood glucose by improving tar...more |
| T3D4796 | Anastrozole | 120511-73-1 | Anastrozole selectively inhibits aromatase. The principal source of circulating estrogen (primari...more |
| T3D4798 | Iopanoic acid | 96-83-3 | Not Available |
| T3D4803 | Letrozole | 112809-51-5 | Letrozole is a nonsteroidal competitive inhibitor of the aromatase enzyme system; it inhibits the...more |
| T3D4806 | Aminoglutethimide | 125-84-8 | Aminoglutethimide reduces the production of D5-pregnenolone and blocks several other steps in ste...more |
| T3D4820 | Finasteride | 98319-26-7 | The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-redu...more |
| T3D4821 | Gentian Violet | 14426-25-6 | Gentian Violet is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inh...more |
| T3D4830 | Glycoluril | 496-46-8 | Not Available |
| T3D4834 | Metenamine | 100-97-0 | Not Available |
| T3D4835 | Triethanolamine | 102-71-6 | Not Available |
| T3D4841 | Dimethylethanolamine | 108-01-0 | Not Available |
| T3D4845 | Diethanolamine | 111-42-2 | Not Available |
| T3D4856 | Diphenhydramine | Not Available | Diphenhydramine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase in...more |
| T3D4864 | Erioglaucine A disodium salt | 3844-45-9 | Not Available |
| T3D4868 | 2,6-Diethylaniline | 579-66-8 | Not Available |
| T3D4874 | Ethoxyquin | 91-53-2 | Not Available |
| T3D4891 | Thiourea | 62-56-6 | Not Available |
| T3D4901 | Diethylenetriamine | 111-40-0 | Not Available |
| T3D4916 | Fast green FCF | 2353-45-9 | Not Available |
| T3D4921 | Diflubenzuron | 35367-38-5 | One of the metabolites of diflubenzuron, PCA, is a proximate carcinogen. It is conjugated to form...more |
| T3D4936 | Allantoin | 97-59-6 | Not Available |
| T3D4937 | 4-Hydroxytamoxifen | 68047-06-3 | Not Available |
| T3D4939 | Tridemorph | 81412-43-3 | Not Available |
| T3D4942 | Fenpropimorph | 67306-03-0 and 67564-91-4 | Not Available |
| T3D4946 | 1-Methyl-2-pyrrolidone | 872-50-4 | Not Available |
