Displaying types 21 - 30 of 483 in total

Adrenergic beta-Antagonist (2)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D3480Atenolol29122-68-7Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines ...more
T3D3517Labetalol36894-69-6Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastere...more

Adrenergic Uptake Inhibitor (19)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2480Amitriptyline50-48-6Amitriptyline is metabolized to nortriptyline which inhibits the reuptake of norepinephrine and s...more
T3D2706Amphetamine300-62-9Amphetamines stimulate the release of norepinephrine from central adrenergic receptors. At higher...more
T3D2713Reserpine50-55-5Reserpine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the se...more
T3D2720Reboxetine98769-81-4Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake...more
T3D2737Atomoxetine82248-59-7The precise mechanism by which atomoxetine produces its therapeutic effects in Attention-Deficit/...more
T3D2759Protriptyline438-60-8Protriptyline acts by decreasing the reuptake of norepinephrine and serotonin (5-HT).
T3D2786Methylphenidate113-45-1Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transpo...more
T3D2797Imipramine50-49-7Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and ...more
T3D2805Duloxetine136434-34-9Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a less pot...more
T3D2818Nortriptyline72-69-5It is believed that nortriptyline either inhibits the reuptake of the neurotransmitter serotonin ...more
T3D2819Amoxapine14028-44-5Amoxapine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT).
T3D2830Mazindol22232-71-9Although the mechanism of action of the sympathomimetics in the treatment of obesity is not fully...more
T3D2870Trimipramine739-71-9Trimipramine's mechanism of action differs from other tricyclic antidepressants. Trimipramine act...more
T3D2919Benzphetamine156-08-1Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of...more
T3D2934Maprotiline10262-69-8Maprotiline exerts its antidepressant action by inhibition of presynaptic uptake of catecholamine...more
T3D2993Doxepin1668-19-5The mechanism of action of doxepin is not completely understood. It is thought that like amitript...more
T3D2996Desipramine50-47-5Desipramine is a tricyclic antidepressant (TCA) that selectively blocks reuptake of norepinephrin...more
T3D3051Dextroamphetamine51-64-9The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinep...more
T3D3052Methamphetamine537-46-2Methamphetamine enters the brain and triggers a cascading release of norepinephrine, dopamine and...more

Aerosol Spray Component (3)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D4591Nitrous oxide10024-97-2Not Available
T3D46602-Chlorobenzylidene malononitrile2698-41-1Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary ...more
T3D4664Dimethyl ether115-10-6Not Available

Affinity Label (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D4149Guanidoacetic acid352-97-6Uremic toxins such as guanidinoacetic acid are actively transported into the kidneys via organic ...more

Alcohol Antagonist (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2864Naltrexone16590-41-3Naltrexone is a pure opiate antagonist and has little or no agonist activity. The mechanism of ac...more

Alcohol Deterrent (2)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2557Disulfiram97-77-8Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism fo...more
T3D2853Acamprosate77337-76-9The mechanism of action of acamprosate in maintenance of alcohol abstinence is not completely und...more

Aldehyde (31)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D0037Acrolein107-02-8Acrolein rapidly and irreversibly binds to lysine moieties and sulfhydryl groups found on many ce...more
T3D0069Endrin aldehyde7421-93-4Endrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at th...more
T3D0204Pentachlorodibenzo-p-dioxin36088-22-9CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently alter...more
T3D0244Formaldehyde50-00-0It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde de...more
T3D0319Lead acetate301-04-2Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as co...more
T3D2550Onchidal67656-42-2Onchidal is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor...more
T3D2645Brevetoxin98112-41-5Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to...more
T3D3471Acetaldehyde75-07-0Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (A354)
T3D4034Brevetoxin B2Not AvailableNot Available
T3D4041Convalloside13473-51-3Not Available
T3D4067Convallatoxin508-75-8Convallatoxin (CNT) is classified as a cardiac glycoside. Cardiac glycosides are well known Na+/K...more
T3D4104Strophanthidin66-28-4Not Available
T3D4112PR-toxin56299-00-4Not Available
T3D4114alpha-Antiarin23605-05-2Not Available
T3D4128Brevetoxin B79580-28-2Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to...more
T3D4141Hemibrevetoxin B122271-91-4Not Available
T3D4181Hexanal66-25-1Uremic toxins such as hexanal are actively transported into the kidneys via organic ion transport...more
T3D4183Decanal112-31-2Uremic toxins such as decanal are actively transported into the kidneys via organic ion transport...more
T3D41862-Octenal2363-89-5Uremic toxins such as 2-Octenal are actively transported into the kidneys via organic ion transpo...more
T3D41872-Nonenal2463-53-8Uremic toxins such as 2-Nonenall are actively transported into the kidneys via organic ion transp...more
T3D4188Heptanal111-71-7Uremic toxins such as heptanal are actively transported into the kidneys via organic ion transpor...more
T3D41892-Hexenal505-57-7Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transpo...more
T3D41902-Heptenal2463-63-0Uremic toxins such as 2-Heptenal are actively transported into the kidneys via organic ion transp...more
T3D41914-Decenal30390-50-2Uremic toxins such as 4-Decenal are actively transported into the kidneys via organic ion transpo...more
T3D4192Nonanal124-19-6Uremic toxins such as nonanal are actively transported into the kidneys via organic ion transport...more
T3D41944-Hydroxyhexanal109710-36-3Uremic toxins such as 4-Hydroxyhexenall are actively transported into the kidneys via organic ion...more
T3D41954-Hydroxyoctenal17449-15-9Uremic toxins such as 4-Hydroxyoctenal are actively transported into the kidneys via organic ion ...more
T3D46324-(N-Methyl-N-nitrosamino)-1-butanoneNot AvailableNot Available
T3D4844Glutaral111-30-8Not Available
T3D4898Chloroacetaldehyde107-20-0Not Available
T3D49082-Pentyl-3-phenyl-2-propenal122-40-7Not Available

Alkylating Agent (3)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2743Mitomycin50-07-7Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to D...more
T3D4204Mechlorethamine51-75-2Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases,...more
T3D4750Busulfan55-98-1Busulfan is an alkylating agent that contains 2 labile methanesulfonate groups attached to opposi...more

Aluminum Compound (84)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D0187Aluminum7429-90-5The main targets of aluminum are the central nervous system and bones. Aluminum binds to dietary ...more
T3D1289Aluminium arsenide22831-42-1Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of th...more
T3D1374Cadmium(I) tetrachloroaluminate79110-87-5Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are ob...more
T3D1414Nickel aluminide12003-78-0Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin...more
T3D1486Aluminium chlorohydrate1327-41-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1487Aluminium diacetate hydroxide142-03-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1488Aluminum triacetate139-12-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1489Aloglutamol13755-41-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1490Aluminium acetoacetate19022-77-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1491Aluminium antimonide25152-52-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1492Aluminium carbide1299-86-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1493Aluminium chloride7446-70-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1495Aluminium diboride12041-50-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1496Aluminium dodecaboride12041-54-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1497Aluminium lactate7784-18-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1499Potassium aluminium fluoride14484-69-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1501Dihydroxyaluminium13682-92-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1502Aluminium hydride7784-21-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1503Lithium aluminium hydride16853-85-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1504Aluminium hydroxide21645-51-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1505Aluminium iodide7784-23-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1507Aluminium(I) oxide12004-36-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1508Aluminium(II) oxide457-64-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1509Aluminium(III) oxide1344-28-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1510Aluminium isopropoxide555-31-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1511Aluminium molybdate15123-80-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1512Aluminium monochloride13595-81-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1513Aluminium monofluoride13595-82-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1514Aluminium monostearate7047-84-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1515Aluminium nitrate13473-90-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1517Aluminium nitride24304-00-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1518Aluminium oxynitride12633-97-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1519Aluminium phosphate7784-30-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1520Aluminium phosphide20859-73-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1521Aluminium silicate1335-30-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1522Aluminium sulfate10043-01-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1524Aluminium sulfide1302-81-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1525Methylaluminoxane120144-90-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1526Aluminum ammonium sulfate7784-25-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1528Diisobutylaluminium hydride1191-15-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1529Potassium alum10043-67-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1531Sodium bis(2-methoxyethoxy)aluminumhydride22722-98-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1532Sodium aluminium hydride13770-96-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1533Sodium hexafluoroaluminate13775-53-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1534Tebbe's reagent67719-69-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1535Triethylaluminium97-93-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1536Trimethylaluminium75-24-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1537Tris(8-hydroxyquinolinato)aluminium2085-33-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1538Lithium aluminate12003-67-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1539Sodium aluminate1302-42-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1540Strontium aluminate12004-37-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1541Magnesium aluminate12068-51-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1542Tantalum(III) aluminide12004-76-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1543Titanium aluminide12003-96-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1544Lithium tetrachloroaluminate14024-11-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1545Dichloroethylaluminum563-43-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1546Aluminum sodium sulfate10102-71-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1547Aluminum palmitate555-35-1The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1548Aluminum oleate688-37-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1549Sodium aluminum phosphate7785-88-8The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1550Triisobutylaluminum100-99-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1551Ethylaluminum sesquichloride12075-68-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1552Methyl aluminum sesquibromide12263-85-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1553Chlorodiethyaluminum96-10-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1554Aluminum ethylate555-75-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1555Aluminum distearate300-92-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1556Aluminium octadecanoate637-12-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1557Tri-n-ocylaluminum1070-00-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1558Tri-n-butylaluminum16-70-7The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1559Tri-n-hexylaluminum1116-73-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1560Trieicosylaluminum1529-57-3The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1561Tritetradecylaluminum1529-58-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1562Tris(dodecyl)aluminum1529-59-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1563Trihexadecylaluminum1726-65-4The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1564Tri-n-decylaluminum1726-66-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1565Bis(isobutyl)aluminum chloride1779-25-5The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1566Aluminum calcium sodium silicate44-01-0The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1567Diaspore14457-84-2The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1568gamma-Aluminum oxide hydroxide1318-23-6The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1571Aluminum butylate2269-22-9The main target organs of aluminum are the central nervous system and bone. Aluminum binds with d...more
T3D1572Allylpalladium chloride dimer12012-95-2Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more
T3D1573Palladium acetylacetonate24-61-4Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ...more
T3D1720Aluminium bromide7727-15-3Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water ...more
T3D1828Aluminium selenide1302-82-5Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especi...more

Amebicide (1)

T3DB IDCommon nameCAS NumberMechanism of Toxicity
T3D2561Chloroquine54-05-7The mechanism of plasmodicidal action of chloroquine is not completely certain. Like other quinol...more
Displaying types 21 - 30 of 483 in total