Browsing Toxin Types
Anti-Ulcer Agent (5)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2810 | Cimetidine | 51481-61-9 | Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal ce...more |
| T3D2836 | Cisapride | 81098-60-4 | Cisapride acts through the stimulation of the serotonin 5-HT4 receptors which increases acetylcho...more |
| T3D2873 | Esomeprazole | 161796-78-7 | Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibi...more |
| T3D2957 | Balsalazide | 80573-04-2 | The mechanism of action of 5-aminosalicylic acid is unknown, but appears exert its anti-inflammat...more |
| T3D3524 | Omeprazole | 73590-58-6 | Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibiti...more |
Anti-Wrinkle Agent (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3583 | Botulinum toxin | 93384-43-1 | Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond ...more |
Antibiotic (9)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2788 | Streptozocin | 18883-66-4 | Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-produc...more |
| T3D2822 | Pentostatin | 53910-25-1 | Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest act...more |
| T3D2861 | Daunorubicin | 20830-81-3 | Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of ac...more |
| T3D2951 | Neomycin | 1404-04-2 | Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. ...more |
| T3D2953 | Doxorubicin | 23214-92-8 | Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of act...more |
| T3D2968 | Gatifloxacin | 112811-59-3 | The bactericidal action of Gatifloxacin results from inhibition of the enzymes topoisomerase II (...more |
| T3D2969 | Rifampin | 13292-46-1 | Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA...more |
| T3D3000 | Trimetrexate | 52128-35-5 | In vitro studies have shown that trimetrexate is a competitive inhibitor of dihydrofolate reducta...more |
| T3D3497 | Clindamycin | 18323-44-9 | Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosom...more |
Antibiotic, Antifungal (3)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2763 | Anidulafungin | 166663-25-8 | Anidulafungin is a semi-synthetic echinocandin with antifungal activity. Anidulafungin inhibits g...more |
| T3D2964 | Cerulenin | 17397-89-6 | Irreversibly binds to fatty acid synthase, specifically b-ketoacyl-acyl carrier protein synthase ...more |
| T3D3035 | Posaconazole | 171228-49-2 | As a triazole antifungal agent, posaconazole exerts its antifungal activity through blockage of t...more |
Antibiotic, Antineoplastic (8)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2738 | Bleomycin | 11056-06-7 | It has been suggested that bleomycin induces sensitivity to oxygen toxicity and recent studies su...more |
| T3D2743 | Mitomycin | 50-07-7 | Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to D...more |
| T3D2788 | Streptozocin | 18883-66-4 | Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-produc...more |
| T3D2791 | Epirubicin | 56420-45-2 | Epirubicin has antimitotic and cytotoxic activity. It inhibits nucleic acid (DNA and RNA) and pro...more |
| T3D2861 | Daunorubicin | 20830-81-3 | Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of ac...more |
| T3D2921 | Sirolimus | 53123-88-9 | Sirolimus inhibits T lymphocyte activation and proliferation that occurs in response to antigenic...more |
| T3D2953 | Doxorubicin | 23214-92-8 | Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of act...more |
| T3D2960 | Mycophenolic acid | 24280-93-1 | Mycophenolic acid is a potent, selective, uncompetitive, and reversible inhibitor of inosine mono...more |
Antibiotic, Antitubercular (4)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2838 | Rifabutin | 72559-06-9 | Rifabutin acts via the inhibition of DNA-dependent RNA polymerase in gram-positive and some gram-...more |
| T3D2863 | Amprenavir | 161814-49-9 | Amprenavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polypr...more |
| T3D2969 | Rifampin | 13292-46-1 | Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA...more |
| T3D3018 | Rifapentine | 61379-65-5 | Rifapentine has shown higher bacteriostatic and bactericidal activities especially against intrac...more |
Antibiotic, Topical (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3068 | Silver sulfadiazine | 22199-08-2 | Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemica...more |
Anticancer Agent (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3533 | Sorafenib | 284461-73-0 | Sorafenib interacts with multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kin...more |
Anticarcinogenic Agent (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3963 | Genistein | 446-72-0 | Genistein may inhibit cancer cell growth by blocking enzymes required for cell growth. Genistei...more |