Browsing Toxin Types
Trace Element (2)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D0074 | Zinc | 7440-66-6 | Excessive zinc intake alters copper and iron absorption, most likely through competitive binding ...more |
| T3D4697 | Iron | 7439-89-6 | Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased product...more |
Trypanocidal Agent (2)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3035 | Posaconazole | 171228-49-2 | As a triazole antifungal agent, posaconazole exerts its antifungal activity through blockage of t...more |
| T3D3526 | Pentamidine | 100-33-4 | The mode of action of pentamidine is not fully understood. It is thought that the drug interferes...more |
Tubulin Modulator (7)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2479 | Vindesine | 53643-48-4 | Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin...more |
| T3D3476 | Albendazole | 54965-21-8 | Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by b...more |
| T3D4016 | Vincristine | 57-22-7 | The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at ...more |
| T3D4017 | Vinblastine | 865-21-4 | The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at ...more |
| T3D4019 | Paclitaxel | 33069-62-4 | Paclitaxel interferes with the normal function of microtubule growth. Whereas drugs like colchici...more |
| T3D4020 | Colchicine | 64-86-8 | Colchicine inhibits microtubule assembly in various cells, including leukocytes, probably by bind...more |
| T3D4617 | Podofilox | 477-47-4 | Etoposide, a semisynthetic derivative of podofilox, induces DNA breakage through its inhibition o...more |
Uncoupling Agent (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3735 | Dicumarol | 66-76-2 | Dicoumarol is an anticoagulant that competitively inhibits vitamin K, preventing the formation of...more |
Uranium Compound (26)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D0108 | Uranium-235 | 15117-96-1 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D0111 | Uranium-234 | 13966-29-5 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D0179 | Uranium-233 | 13968-55-3 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D0791 | Uranium-238 | 7440-61-1 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1160 | Ammonium diuranate | 7783-22-4 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1161 | Sodium uranate | 13721-34-1 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1162 | Triuranium octaoxide | 1344-59-8 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1163 | Uranium dioxide | 1344-57-6 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1164 | Uranium hexafluoride | 7783-81-5 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1165 | Uranium pentachloride | 13470-21-8 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1166 | Uranium peroxide | 12036-71-4 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1167 | Uranium tetrachloride | 10026-10-5 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1168 | Uranium pentafluoride | 10049-14-6 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1169 | Uranium trioxide | 1344-58-6 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1170 | Uranyl fluoride | 13536-84-0 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1172 | Uranium boride | 12007-36-2 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1173 | Uranium carbide | 12070-09-6 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1174 | Uranium nitride | 12033-83-9 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1175 | Uranium chloride | 10025-93-1 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1176 | Uranocene | 11079-26-8 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1177 | Uranyl acetate | 541-09-3 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1179 | Uranyl chloride | 7791-26-6 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1180 | Uranyl formate | 16984-59-1 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1181 | Uranyl nitrate | 10102-06-4 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1182 | Uranyl sulfate | 1314-64-3 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
| T3D1183 | Uranyl zinc acetate | 10138-94-0 | Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidn...more |
Uremic Toxin (56)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D0170 | p-Cresol | 106-44-5 | p-Cresol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor...more |
| T3D0227 | Cresols | 1319-77-3 | Cresols is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor ...more |
| T3D4148 | Dimethylamine | 124-40-3 | Uremic toxins such as dimethylamine are actively transported into the kidneys via organic ion tra...more |
| T3D4149 | Guanidoacetic acid | 352-97-6 | Uremic toxins such as guanidinoacetic acid are actively transported into the kidneys via organic ...more |
| T3D4150 | Hypoxanthine | 68-94-0 | Hypoxanthine is a poorly soluble compound. As a result high concentrations of serum hypoxanthine...more |
| T3D4151 | Methylamine | 74-89-5 | Uremic toxins such as methylamine are actively transported into the kidneys via organic ion trans...more |
| T3D4152 | Indoleacetic acid | 87-51-4 | Uremic toxins such as indole-3-acetic acid are actively transported into the kidneys via organic ...more |
| T3D4153 | Phenylacetic acid | 103-82-2 | Uremic toxins such as phenylacetic acid are actively transported into the kidneys via organic ion...more |
| T3D4154 | Norepinephrine | 51-41-2 | Uremic toxins such as noradrenalin are actively transported into the kidneys via organic ion tran...more |
| T3D4155 | Uric acid | 69-93-2 | Uremic toxins such as uric acid are actively transported into the kidneys via organic ion transpo...more |
| T3D4156 | L-Cysteine | 52-90-4 | Uremic toxins such as cysteine are actively transported into the kidneys via organic ion transpor...more |
| T3D4157 | Indican | 1336-79-4 | Uremic toxins such as indican are actively transported into the kidneys via organic ion transport...more |
| T3D4158 | Indoxyl sulfate | 487-94-5 | Uremic toxins such as Indoxyl sulfate are actively transported into the kidneys via organic ion t...more |
| T3D4159 | Hippuric acid | 495-69-2 | Uremic toxins such as hippuric acid are actively transported into the kidneys via organic ion tra...more |
| T3D4160 | Kynurenic acid | 492-27-3 | Uremic toxins such as kynurenic acid are actively transported into the kidneys via organic ion tr...more |
| T3D4161 | Homocysteine | 454-29-5 | Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, whi...more |
| T3D4162 | Neopterin | 2009-64-5 | Uremic toxins such as neopterin are actively transported into the kidneys via organic ion transpo...more |
| T3D4163 | Trimethylamine | 75-50-3 | Uremic toxins such as trimethylamine are actively transported into the kidneys via organic ion tr...more |
| T3D4164 | Trimethylamine N-oxide | 1184-78-7 | Uremic toxins such as TMAO are actively transported into the kidneys via organic ion transporters...more |
| T3D4165 | 2-Aminobenzoic acid | 118-92-3 | Uremic toxins such as anthranilic acid are actively transported into the kidneys via organic ion ...more |
| T3D4166 | Spermine | 71-44-3 | Uremic toxins such as spermine are actively transported into the kidneys via organic ion transpor...more |
| T3D4167 | Spermidine | 124-20-9 | Uremic toxins such as spermidine are actively transported into the kidneys via organic ion transp...more |
| T3D4168 | Niacinamide | 98-92-0 | Uremic toxins such as nicotinamide are actively transported into the kidneys via organic ion tran...more |
| T3D4169 | Putrescine | 110-60-1 | Uremic toxins such as putrescine are actively transported into the kidneys via organic ion transp...more |
| T3D4170 | Methylguanidine | 471-29-4 | Uremic toxins such as methylguanidine are actively transported into the kidneys via organic ion t...more |
| T3D4171 | Asymmetric dimethylarginine | 30315-93-6 | Uremic toxins such as asymmetric dimethylarginine are actively transported into the kidneys via o...more |
| T3D4172 | Guanidine | 113-00-8 | Uremic toxins such as guaniidine are actively transported into the kidneys via organic ion transp...more |
| T3D4173 | Argininic acid | 157-07-3 | Uremic toxins such as arginic acid are actively transported into the kidneys via organic ion tran...more |
| T3D4174 | Guanidinosuccinic acid | 6133-30-8 | Uremic toxins such as guanidinosuccinic acid are actively transported into the kidneys via organi...more |
| T3D4175 | 8-Hydroxy-deoxyguanosine | 88847-89-6 | Uremic toxins such as 8-Hydroxy-2Х-deoxyguanosine are actively transported into the kidneys via o...more |
| T3D4176 | Symmetric dimethylarginine | 30344-00-4 | Uremic toxins such as symmetric dimethylarginine are actively transported into the kidneys via or...more |
| T3D4177 | Pentosidine | 124505-87-9 | Uremic toxins such as pentosidine are actively transported into the kidneys via organic ion trans...more |
| T3D4178 | N1-Methyl-2-pyridone-5-carboxamide | 701-44-0 | Uremic toxins such as N-methyl-2-pyridone-5-carboxamide are actively transported into the kidneys...more |
| T3D4179 | N1-Methyl-4-pyridone-3-carboxamide | 769-49-3 | Uremic toxins such as N-methyl-4-pyridone-3-carboxamide are actively transported into the kidneys...more |
| T3D4180 | 4-Hydroxynonenal | 75899-68-2 | Uremic toxins such as 4-Hydroxynonenal are actively transported into the kidneys via organic ion ...more |
| T3D4181 | Hexanal | 66-25-1 | Uremic toxins such as hexanal are actively transported into the kidneys via organic ion transport...more |
| T3D4182 | Malondialdehyde | 542-78-9 | Uremic toxins such as malondialdehyde are actively transported into the kidneys via organic ion t...more |
| T3D4183 | Decanal | 112-31-2 | Uremic toxins such as decanal are actively transported into the kidneys via organic ion transport...more |
| T3D4184 | p-Cresol sulfate | 3233-58-7 | Uremic toxins such as p-Cresol sulfate are actively transported into the kidneys via organic ion ...more |
| T3D4185 | Ethylamine | 75-04-7 | Uremic toxins such as ethylamine are actively transported into the kidneys via organic ion transp...more |
| T3D4186 | 2-Octenal | 2363-89-5 | Uremic toxins such as 2-Octenal are actively transported into the kidneys via organic ion transpo...more |
| T3D4187 | 2-Nonenal | 2463-53-8 | Uremic toxins such as 2-Nonenall are actively transported into the kidneys via organic ion transp...more |
| T3D4188 | Heptanal | 111-71-7 | Uremic toxins such as heptanal are actively transported into the kidneys via organic ion transpor...more |
| T3D4189 | 2-Hexenal | 505-57-7 | Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transpo...more |
| T3D4190 | 2-Heptenal | 2463-63-0 | Uremic toxins such as 2-Heptenal are actively transported into the kidneys via organic ion transp...more |
| T3D4191 | 4-Decenal | 30390-50-2 | Uremic toxins such as 4-Decenal are actively transported into the kidneys via organic ion transpo...more |
| T3D4192 | Nonanal | 124-19-6 | Uremic toxins such as nonanal are actively transported into the kidneys via organic ion transport...more |
| T3D4193 | 4-Hydroxydecenal | 73529-64-3 | Uremic toxins such as 4-Hydroxydecenal are actively transported into the kidneys via organic ion ...more |
| T3D4194 | 4-Hydroxyhexanal | 109710-36-3 | Uremic toxins such as 4-Hydroxyhexenall are actively transported into the kidneys via organic ion...more |
| T3D4195 | 4-Hydroxyoctenal | 17449-15-9 | Uremic toxins such as 4-Hydroxyoctenal are actively transported into the kidneys via organic ion ...more |
| T3D4196 | Alpha-keto-delta-guanidinovaleric acid | 3715-10-4 | Uremic toxins such as alpha-keto-delta-guanidinoacetic acid are actively transported into the kid...more |
| T3D4197 | 3-Carboxy-4-methyl-5-propyl-2-furan-propanoic acid | 86879-39-2 | Uremic toxins such as 3-Carboxy-4-methyl-5-propyl-2-furan-propanoic acid are actively transported...more |
| T3D4198 | N(6)-Carboxymethyllysine | 5746-04-3 | Uremic toxins such as carboxymethyllysine are actively transported into the kidneys via organic i...more |
| T3D4199 | Dihydroxyphenylalanine | 63-84-3 | Uremic toxins such as dihydroxyphenylalanine are actively transported into the kidneys via organi...more |
| T3D4200 | Inodxyl glucuronide | 35804-66-1 | Uremic toxins such as indoxyl-beta-D-glucuronide are actively transported into the kidneys via or...more |
| T3D4213 | 2-Aminonaphthalene | 91-59-8 | Not Available |
Urinary Antispasmodic (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D3499 | Darifenacin | 133099-04-4 | Darifenacin selectively antagonizes the muscarinic M3 receptor. M3 receptors are involved in cont...more |
Urticant (1)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D4653 | Phosgene oxime | 1794-86-1 | Not Available |
Vanadium Compound (24)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D0198 | Vanadium | 7440-62-2 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1624 | Vanadium carbide | 12070-10-9 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1625 | Vanadium carbonyl | 20644-87-5 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1626 | Vanadium nitride | 24646-85-3 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1627 | Vanadium oxytrichloride | 7727-18-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1628 | Vanadium tetrachloride | 7632-51-1 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1629 | Vanadium(II) chloride | 10580-52-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1630 | Vanadium(II) oxide | 12035-98-2 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1631 | Vanadium(III) chloride | 7718-98-1 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1632 | Vanadium(III) fluoride | 10049-12-4 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1633 | Vanadium(III) iodide | 15513-94-7 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1634 | Vanadium(III) oxide | 1314-34-7 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1635 | Vanadium(III) sulfate | 13701-70-7 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1636 | Vanadium(IV) fluoride | 10049-16-8 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1637 | Vanadyl sulfate | 27774-13-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1638 | Vanadium(IV) oxide | 12036-21-4 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1639 | Vanadium(V) oxide | 1314-62-1 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1640 | Vanadium(V) oxytrifluoride | 13709-31-4 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1641 | Vanadocene dichloride | 12083-48-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1642 | Vanadyl acetylacetonate | 3153-26-2 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1645 | Ammonium metavanadate | 7803-55-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1646 | Sodium metavanadate | 13718-26-8 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1647 | Sodium orthovanadate | 13721-39-6 | Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impai...more |
| T3D1768 | Vanadium(III) bromide | 13470-26-3 | Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water ...more |
Vapour (4)
| T3DB ID | Common name | CAS Number | Mechanism of Toxicity |
|---|---|---|---|
| T3D2563 | Carbon dioxide | 124-38-9 | Carbon dioxide causes widespread activation of the sympathetic nervous system and an increase in ...more |
| T3D3426 | n-Butane | 106-97-8 | Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the centr...more |
| T3D3427 | Isobutane | 75-28-5 | Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the centr...more |
| T3D4972 | Chlorine gas | 7782-50-5 | Chlorine is a strong oxidizer that hydrolyzes in water forming hydrochloric and hypochlorous acid...more |